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The field of Epigenetics represents the science which helps us understand the influence life has on genetic function. Research has shown that what we do, what we are exposed to, and the internal and external environments have significant influence on the output of our genes. In this article, the reader will understand how alterations in the DNA explain
Dale, Jeremy, Hillman, Sarah C
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Environmental Epigenetics update [PDF]
Environmental Epigenetics, an Oxford University Press publication, just initiated its seventh year of operations with this Volume 7 Issue 1. We are a completely 100% Open Access journal listed in PMC and PubMed, along with numerous other access sites ...
Skinner, Michael K
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Computational epigenetics [PDF]
Abstract Epigenetic research aims to understand heritable gene regulation that is not directly encoded in the DNA sequence. Epigenetic mechanisms such as DNA methylation and histone modifications modulate the packaging of the DNA in the nucleus and thereby influence gene expression.
Christoph Bock, Thomas Lengauer
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Environmental epigenetics and climate change [PDF]
Epigenetics co-evolved with deoxyribonucleic acid sequence as the molecular mechanism to regulate gene expression and chromatin structure and provide the conduit for the environment to influence biology and evolution.
Skinner, Michael K, Skinner, Michael K.
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The best-known phenomenon exemplifying epigenetic drift (the alteration of epigenetic patterns during aging) is the gradual decrease of global DNA methylation. Aging cells, different tissue types, as well as a variety of human diseases possess their own distinct DNA methylation profiles, although the functional impact of these is not always clear.
Sierra, Marta I. +2 more
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Environmental Epigenetics [PDF]
With over 350 journals, Oxford University Press is one of the largest publishers of scientific journals. In considering their portfolio recently, they realized they had no specific journals in the rapidly growing area of epigenetics. When they approached
Skinner, Michael K
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Objectives: Recent evidence from the fields of microbiology and immunology, as well as a small number of human sepsis studies, suggest that epigenetic regulation may play a central role in the pathogenesis of sepsis. The term “epigenetics” refers to regulatory mechanisms that control gene expression but are not related to ...
Binnie, Alexandra +5 more
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Epigenetics and Lifestyle [PDF]
The concept of 'lifestyle' includes different factors such as nutrition, behavior, stress, physical activity, working habits, smoking and alcohol consumption. Increasing evidence shows that environmental and lifestyle factors may influence epigenetic mechanisms, such as DNA methylation, histone acetylation and miRNA expression.
J. A. Alegría Torres +2 more
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Novel DNA methylation profiles associated with key gene regulation and transcription pathways in blood and placenta of growth-restricted neonates [PDF]
Fetal growth is determined by the feto-placental genome interacting with the maternal in utero environment. Failure of this interplay leads to poor placental development and fetal growth restriction (FGR), which is associated with future metabolic ...
Lowe, R +8 more
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Epigenetics and depression [PDF]
The risk for major depression is both genetically and environmentally determined. It has been proposed that epigenetic mechanisms could mediate the lasting increases in depression risk following exposure to adverse life events and provide a mechanistic framework within which genetic and environmental factors can be integrated.
Penner-Goeke, S. +1 more
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