Results 81 to 90 of about 458,162 (417)
DNA methylation analysis of the angiotensin converting enzyme (ACE) gene in major depression. [PDF]
, 2012 The angiotensin converting enzyme (ACE) has been repeatedly discussed as susceptibility factor for major depression (MD) and the bi-directional relation between MD and cardiovascular disorders (CVD).
Baghai, Thomas C. +11 more
core +2 more sources
Scientific Reports, 2023 We recently introduced an absolute and physical quantitative scale for chromatin immunoprecipitation followed by sequencing (ChIP-seq). The scale itself was determined directly from measurements routinely made on sequencing samples without additional ...
Bradley M. Dickson +3 more
doaj +1 more source
An Epigenetic Role of Mitochondria in Cancer
Cells, 2022 Mitochondria are not only the main energy supplier but are also the cell metabolic center regulating multiple key metaborates that play pivotal roles in epigenetics regulation.
Yu’e Liu +6 more
doaj +1 more source
PLoS Biology, 2010 Imagine—you’ve just been born, and your future looks bleak. After an all-too brief infancy when you’ll be cared for and fed, you’ll be forced into child labour, cleaning a dark and crowded home and caring for your many siblings. You’ll be subsequently put on guard duty to defend your home against vicious intruders. If you survive, you’ll spend the rest
Chittka, A, Chittka, L
openaire +6 more sources
The physics of epigenetics [PDF]
Reviews of Modern Physics, 2016 In higher organisms, all cells share the same genome, but every cell expresses only a limited and specific set of genes that defines the cell type. During cell division, not only the genome, but also the cell type is inherited by the daughter cells.
Cortini, Ruggero +6 more
openaire +4 more sources
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Dynamics of cell-type transition mediated by epigenetic modifications [PDF]
arXiv, 2023 Maintaining tissue homeostasis requires appropriate regulation of stem cell differentiation. The Waddington landscape posits that gene circuits in a cell form a potential landscape of different cell types, wherein cells follow attractors of the probability landscape to develop into distinct cell types.
arxiv
The Impact of Nutrition and Environmental Epigenetics on Human Health and Disease
International Journal of Molecular Sciences, 2018 Environmental epigenetics describes how environmental factors affect cellular epigenetics and, hence, human health. Epigenetic marks alter the spatial conformation of chromatin to regulate gene expression.
C. Tiffon
semanticscholar +1 more source
Epigenetic regulation of adaptive responses of forest tree species to the environment [PDF]
, 2013 Epigenetic variation is likely to contribute to the phenotypic plasticity and adaptative capacity of plant species, and may be especially important for long-lived organisms with complex life cycles, including forest trees.
Akimoto +114 more
core +4 more sources