Results 91 to 100 of about 63,478 (191)

Epigenome-wide meta-analysis of CD8+ T-cell DNA methylation in three combined cohorts for HIV infection.

Epigenome-wide meta-analysis of CD8+ T-cell DNA methylation in three combined cohorts for HIV infection.
Vincent C. Marconi (8232468), Bradley E. Aouizerat (9678480), Xinyu Zhang (14029), Mardge H. Cohen (7923182), Ral E. Vandenhoudt (18137407), Zuoheng Wang (223293), Ying Hu (14950), Ke Xu (134879), Amy C. Justice (9185633), Chunhua Yan (392686)   +9 more
core   +1 more source

Epigenome-wide association study reveals a molecular signature of response to phylloquinone (vitamin K1) supplementation

, 2020
Evidence suggests there are roles for vitamin K in various chronic disease outcomes, but population-level diet and supplement recommendations are difficult to determine due to high levels of variability in measures of status and response to intake ...
Sarah L. Booth (8484639), Jennifer M. Kelly (8536935), Kenneth Westerman (7504673), José M. Ordovás (5648779), Dawn L. DeMeo (8484642)   +4 more
core   +1 more source

Short-term heavy drinking in a non-human primate model skews monocytes toward a hypo-inflammatory phenotype

Frontiers in Immunology
IntroductionAlcohol use is prevalent in the United States (US), with ~80% of persons over 12 years old reporting alcohol consumption in 2023 and ~10% of those individuals developing alcohol use disorder (AUD).
Madison B. Blanton, Madison B. Blanton, Hami Hemati, Qi Qiao, Qi Qiao, Rupak Khadka, Gregory Hawk, Kathleen A. Grant, Ilhem Messaoudi   +8 more
doaj   +1 more source

Epigenome-wide meta-analysis of CD4+ T-cell DNA methylation in three combined cohorts for HIV infection, top 500.

Epigenome-wide meta-analysis of CD4+ T-cell DNA methylation in three combined cohorts for HIV infection, top 500.
Vincent C. Marconi (8232468), Bradley E. Aouizerat (9678480), Xinyu Zhang (14029), Mardge H. Cohen (7923182), Ral E. Vandenhoudt (18137407), Zuoheng Wang (223293), Ying Hu (14950), Ke Xu (134879), Amy C. Justice (9185633), Chunhua Yan (392686)   +9 more
core   +1 more source

Epigenome-wide association study of long-term psychosocial stress in older adults

Long-term psychosocial stress is strongly associated with negative physical and mental health outcomes, as well as adverse health behaviours; however, little is known about the role that stress plays on the epigenome.
Jessica D. Faul (3944534), Jennifer A. Smith (7726103), Scott M. Ratliff (4227004), Belinda L. Needham (9665997), Wei Zhao (14321), Lauren A. Opsasnick (18091549), Xiang Zhou (164107), Lauren L. Schmitz (11083389)   +7 more
core   +1 more source

Epigenome-wide analysis across the development span of pediatric acute lymphoblastic leukemia: backtracking to birth

Epigenome-wide analysis across the development span of pediatric acute lymphoblastic leukemia: backtracking to ...
R Saffery (842916), J Nordlund (20286051), N Spitz (20286027), JA McKay (16373553), Z Herceg (7770737), FJ Nassar (20286024), MS Pearce (15807182), R Roy (13407462), AJ de Smith (20286048), J Casement (20286039), O Krali (20286030), SE Håberg (13965834), T Dwyer (9865814), Peter Fransquet (13070280), G Strathdee (20286042), D Lam (8679525), E Nickels (20286033), S Li (5107748), YS Lee (14171922), A Novoloaca (16309809), V Cahais (20286036), D Sinnett (8450571), P Magnus (7739087), SG Nusslé (20286021), M Caron (8450562), HM Hansen (20286045), HH Lee (6699971), A Ghantous (16142327), JL Wiemels (16309872), C Cuenin (15991067), MC Munthe-Kaas (16309875)   +30 more
core  

Chemical catalyst manipulating cancer epigenome and transcription [PDF]

Post-translational modification (PTM) of histones dynamically regulates gene transcription and is closely related to cancer development. Altering the epigenome is thus a promising strategy for cancer chemotherapy.
Atsushi , Kaneda, Atsushi , Iwama, Motomu , Kanai, Yuki , Yamanashi, Yugo , Kamimura, Shinpei , Takamaru, Atsushi , Okabe, Hitoshi , Kurumizaka, Satoshi , Kaito, Kenzo , Yamatsugu, Shigehiro, Kawashima, Tomoya , Kujirai, Yuto , Azumaya   +12 more
core   +2 more sources

DNA Methylation Variation in Blood Cells may Impact Platelet Function

TH Open
DNA methylation modifies nucleotides, regulating gene expression without sequence change. The effects of DNA methylation within blood cell lineages on the development and function of endomitotic high DNA copy megakaryocytes (MKs) to anucleate platelets ...
Jillian Teichman, Ming-Huei Chen, Florian Thibord, Melissa V. Chan, Bongani B. Nkambule, Amber R. Lachapelle, Jiantao Ma, Roby Joehanes, Chunyu Liu, Angel M. Aponte, Sumith R. Panicker, Yogendra Kanthi, Daniel Levy, Andrew D. Johnson   +13 more
doaj   +1 more source

Re-searching nasopharyngeal carcinoma

Guangxi Yike Daxue xuebao
Nasopharyngeal carcinoma (NPC) has been a focus of medical research for more than 100 years, with significant interest emerging over the last 58 years following the identification of the link between the disease and Epstein-Barr virus (EBV) infection ...
Ingemar Ernberg, ZHENG Shixing, ZHOU Xiaoying   +2 more
doaj   +1 more source

Multiomics Screening Identified CpG Sites and Genes That Mediate the Impact of Exposure to Environmental Chemicals on Cardiometabolic Traits

Epigenomes
An understanding of the molecular mechanism whereby an environmental chemical causes a disease is important for the purposes of future applications. In this study, a multiomics workflow was designed to combine several publicly available datasets in order
Majid Nikpay
doaj   +1 more source