Results 201 to 210 of about 93,647 (322)
Partial chemical reprogramming significantly increases mitochondrial interaction networks, affects mitochondrial morphology, speeds up mitochondrial movement dynamics, increases mitochondrial transmembrane potential, and induces TCA cycle stress. These changes in mitochondrial function contribute to lipid droplet accumulation, acute kidney injury, and ...
Wayne Mitchell +9 more
wiley +1 more source
A Modular and Customizable CRISPR/Cas Toolkit for Epigenome Editing of Cis-regulatory Modules. [PDF]
Zhang L +6 more
europepmc +1 more source
The Putative Tumor Suppressor microRNA-101 Modulates the Cancer Epigenome by Repressing the Polycomb Group Protein EZH2 [PDF]
Jeffrey M. Friedman +7 more
openalex +1 more source
ABSTRACT Objectives Bipolar disorder (BD) is a common psychiatric disorder with complex genetic and epigenetic underpinnings. This study aimed to investigate whether methylation risk scores (MRSs) derived from epigenome‐wide association studies (EWASs) for BD risk in living peripheral blood and postmortem hippocampal tissues are associated with BD ...
Kazutaka Ohi +6 more
wiley +1 more source
A father's legacy: the sperm epigenome, preimplantation development, and paternal environment. [PDF]
Steg LC, Mansuy IM.
europepmc +1 more source
Power and sample size estimation for epigenome-wide association scans to detect differential DNA methylation [PDF]
Pei-Chien Tsai, Jordana T. Bell
openalex +1 more source
ABSTRACT Renal cell carcinoma (RCC) presents a significant global health challenge, with a substantial proportion of patients diagnosed with advanced or metastatic disease due to the limitations of current diagnostic imaging and the lack of validated non‐invasive biomarkers.
Hossam Kamli, Najeeb Ullah Khan
wiley +1 more source

