A Pilot Epigenome-Wide Study of Posttraumatic Growth: Identifying Novel Candidates for Future Research. [PDF]
Rubens M +8 more
europepmc +1 more source
Restoring the epigenome in Alzheimer's disease: advancing HDAC inhibitors as therapeutic agents
Márcia S. Pereira +3 more
openalex +1 more source
Nanobiotechnology‐Based Approaches for Targeted Glioma Therapy
Nanoparticle systems cross the blood–brain barrier to deliver drugs precisely to glioma cells. Lipid, polymeric, and magnetic carriers enable controlled release, tumor targeting, and microenvironment modulation. These nanoplatforms enhance chemotherapy, radiotherapy, and immunotherapy, improving therapeutic efficacy while reducing systemic toxicity ...
Jinwei Li +11 more
wiley +1 more source
An epigenome-wide association study in the case-control study to explore early development identifies differential DNA methylation near ZFP57 as associated with autistic traits [PDF]
Ellen M. Howerton +15 more
openalex +1 more source
ABSTRACT The effect of the enzyme‐mediated poly(gallic acid) (PGAL) as a potential redox regulator or redox activity compound (RAC) on the morphology of human neuroblastoma SH‐SY5Y cells and its methionine synthase (MS) activities is contrasted to those for disrupting compounds (EDC).
Gabriela García‐Cerón +7 more
wiley +1 more source
Reconstructing epigenomic dynamics through a single-cell multi-epigenome data integration framework. [PDF]
Fujii T +10 more
europepmc +1 more source
Estimating population structure using epigenome-wide methylation data [PDF]
Ziqing Wang +14 more
openalex +1 more source
Comprehensive Mapping of Functional Enhancers in Chinese Hamster Ovary Cells
In this study, the authors identified regions with enhancer activity in the CHO cell genome using genome‐wide and targeted STARR‐seq. The analysis revealed thousands of newly identified enhancer sequences, where some of the most active sequences could drive transgene expression at levels similar to or higher than strong viral enhancers.
María Santos +9 more
wiley +1 more source
The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma
ABSTRACT Metastatic melanoma is the most lethal form of skin cancer, accounting for most skin cancer‐related deaths. Immunotherapies and targeted therapies have improved overall and progression‐free survival rates in metastatic melanoma patients. The effectiveness of these therapies decreases due to multidrug resistance (MDR).
Jacqueline Maphutha +4 more
wiley +1 more source

