Alcohol exposure during development: Impact on the epigenome [PDF]
Amy E. Perkins+3 more
openalex +1 more source
Beyond Conventional Approaches: The Revolutionary Role of Nanoparticles in Breast Cancer
This review explores integrated approach of nanotechnology to breast cancer diagnosis and treatment. We highlight imaging techniques for tumor detection and biomarker analysis in biological samples for early diagnosis. Advanced therapies, including targeted drug delivery and antibody‐drug conjugates, enable precise medication transport to cancer cells,
Mohan Liu+7 more
wiley +1 more source
Epigenetic Applications in Adverse Outcome Pathways and Chemical Risk Evaluation [PDF]
Allard, P+5 more
core
Histone exchange: sculpting the epigenome [PDF]
Marit Terweij, Fred van Leeuwen
openalex +1 more source
Lactylation: From Homeostasis to Pathological Implications and Therapeutic Strategies
Lactylation, a novel post‐translational modification derived from lactate metabolism, plays a critical role in cellular homeostasis and disease pathogenesis. Under physiological conditions, lactylation regulates gene expression, immune responses, and metabolic adaptation. However, dysregulated lactylation is implicated in various pathological processes,
Xi Chen+6 more
wiley +1 more source
Development of a BiAD Sensor for Locus-Specific Detection of Cellular Histone Acetylation Dynamics by Fluorescence Microscopy. [PDF]
Köhler AR+4 more
europepmc +1 more source
Epigenome-wide ovarian cancer analysis identifies a methylation profile differentiating clear-cell histology with epigenetic silencing of the HERG K+ channel [PDF]
Mine S. Cicek+23 more
openalex +1 more source
A comparison of integration methods for single‐cell RNA sequencing data and ATAC sequencing data
Abstract Single‐cell genomics give us a new perspective to understand multivariate phenotypic and genetic effects at the cellular level. Recently, technologies have started measuring different modalities of individual cells, such as transcriptomes, epigenomes, metabolomes, and spatial profiling.
Yulong Kan+5 more
wiley +1 more source
Strengthening Rigor and Reproducibility in Epigenome-Wide Association Studies of Social Exposures and Brain-Based Health Outcomes. [PDF]
McKenna BG+6 more
europepmc +1 more source