Results 251 to 260 of about 93,647 (322)

Epigenetic control of the plant metabolome: implications for Chinese medicine. [PDF]

Chin Med
Hyun TK.
europepmc   +1 more source

Adolescent White Matter Maturation Mediates Epigenetic Associations With Cognitive Development

Developmental Neurobiology, Volume 86, Issue 1, January 2026.
ABSTRACT One hallmark of brain maturation in adolescence is increased myelination (fractional anisotropy [FA]) of the axons, although the epigenetic drivers of this stage of neurodevelopment are as yet poorly understood. Our previous study of a longitudinal cohort of normally developing adolescents, aged nine to fourteen, established the connections ...
Dawn Jensen, Jiayu Chen, Jessica A. Turner, Julia M. Stephen, Yu‐Ping Wang, Tony W. Wilson, Vince D. Calhoun, Jingyu Liu   +7 more
wiley   +1 more source

The Peripheral Epigenome Predicts White Matter Volume Contingent on Developmental Stage: An ECHO Study. [PDF]

Mol Neurobiol
Hanson T, Spencer S, Harker SA, Barry F, Beauchemin J, Braden BB, Burton P, D'sa V, Koinis-Mitchell D, Mennenga SE, Deoni SCL, Lewis CR, on behalf of program collaborators for Environmental influences on Child Health Outcomes.   +12 more
europepmc   +1 more source

Cross‐Species Insights Into Gamma Herpesvirus Transcriptomes: Long‐Read and Multi‐Omics Perspectives

Journal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT Comparative transcriptome analyses of gamma herpesviruses have been revolutionized by long‐read sequencing and integrative multi‐omics approaches, enabling unprecedented resolution of viral gene expression. Cross‐species studies of Kaposi's sarcoma‐associated herpesvirus (KSHV), Epstein–Barr virus (EBV), and murine gamma herpesvirus 68 (MHV68)
Ritu Shekhar, Sarah McMahon, Scott A. Tibbetts, Erik K. Flemington, Rolf Renne   +4 more
wiley   +1 more source

Entropy and Human Aging. [PDF]

Aging Cell
Cummings SR, Hong N, Cohen AA.
europepmc   +1 more source

Ramalin Ameliorates Alzheimer's Disease Pathology by Targeting BACE1, HDAC6, and MAPK Pathways

MedComm, Volume 7, Issue 1, January 2026.
Ramalin alleviates Alzheimer's disease pathology by selectively inhibiting HDAC6, reducing BACE1 levels, and suppressing neuroinflammation through downregulation of the NLRP3 inflammasome and iNOS. It restores synaptic function impaired by Aβ toxicity and improves cognitive performance in AD mouse models, APP/PS1 and 3xTg‐AD.
Yongeun Cho, Jeongmi Lee, Bo Youn Choi, Jin‐Ho Yun, Sukmin Han, Seung Hyun Baek, Jinsu Park, Yoonsuk Cho, Hark Kyun Kim, Eunae Kim, Leon F. Palomera, Jeein Lim, Yeji Jeon, Jeonghyeong Im, Ju‐Mi Hong, Tai Kyoung Kim, Sung Hyun Kim, Joung Han Yim, Dong‐Gyu Jo   +18 more
wiley   +1 more source

Does polypharmacy affect epigenetic aging in older people? Evidence from a longitudinal epigenome-wide methylation study. [PDF]

Clin Epigenetics
Gialluisi A, Tirozzi A, Costanzo S, Licastro D, Di Castelnuovo A, Quiccione MS, Falciglia S, Degasperi M, Panzera T, Magnacca S, Persichillo M, Noro F, Cerletti C, Donati MB, de Gaetano G, Iacoviello L, Moli-sani Study Investigators.   +16 more
europepmc   +1 more source

Emerging Therapeutic Strategies in Anti‐Aging Medicine: A Comprehensive Review

Medicine Bulletin, Volume 2, Issue 1, Page 94-123, January 2026.
ABSTRACT Aging is orchestrated by interconnected hallmarks such as genomic instability, mitochondrial dysfunction, cellular senescence, and disrupted intercellular communication, which collectively drive chronic disease progression. Recent advances have expanded therapeutic opportunities to include pharmacological agents, gene and epigenome editing ...
Yundong Peng, Rui Li, Huan Li, Jun Zhou, Xuanshi Liu, Guilherme Valente, Tatiana de Campos Melo, Sifan Chen, Lei Gu   +8 more
wiley   +1 more source

Editorial: Sperm epigenetic code: implications in reproductive health and paternal contribution to embryo development. [PDF]

Front Cell Dev Biol
Lombò M, Cobellis G, Manfrevola F.
europepmc   +1 more source