Results 261 to 270 of about 86,342 (328)

Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-895, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Ecological Realism Accelerates Epigenetic Aging in Mice

Aging Cell, Volume 24, Issue 6, June 2025.
Living environment shapes mammalian aging, but laboratory conditions lack the ecological realism of natural social, physical, and microbial environments. Comparing traditionally laboratory‐reared and “re‐wilded” C57BL/6J mice, we reveal accelerated, genomic region‐dependent epigenetic aging in the liver under naturalistic field conditions, highlighting
Matthew N. Zipple, Ivan Zhao, Daniel Chang Kuo, Sol Moe Lee, Michael J. Sheehan, Wanding Zhou   +5 more
wiley   +1 more source

Isolating the effects of HIV infection and HIV exposure on epigenetic profiles in infants using historical data from the Mothers and Infants Cohort Study. [PDF]

EBioMedicine
Douglas J, Wang Z, Zumpano F, Satagopan JM, Moye J, Arpadi SM, Marsit CJ, Barrett ES, Shiau S.   +8 more
europepmc   +1 more source

Novel High‐Resolution Lipidomes Could Serve as New Biomarkers for Diabetic Retinopathy: A Bidirectional and Mediated Mendelian Randomization Study

Journal of Cellular and Molecular Medicine, Volume 29, Issue 11, June 2025.
ABSTRACT Although lipid metabolism is a critical factor in the pathogenesis of diabetic retinopathy (DR), the connection between lipidome and DR is still a subject of debate. We aimed to demonstrate that lipidome could serve as novel biomarkers for DR and elucidate the mediating role of inflammatory factors.
Yuxin Sun, Ziran Zhang, Zejun Chen, Zhengran Li, Zijin Wang, Fanye Wu, Xinyu Ma, Shaoyu Wang, Mingzhe Cao, Guoguo Yi, Min Fu   +10 more
wiley   +1 more source

Epigenome editing-mediated restoration of <i>FBN1</i> expression by demethylation of CpG island shore in porcine fibroblasts. [PDF]

Biochem Biophys Rep
Miyadai R, Hinata S, Amemiya Y, Shigematsu S, Umeyama K, Nagashima H, Yamatoya K, Ohgane J.   +7 more
europepmc   +1 more source

Correcting for cell-type composition bias in epigenome-wide association studies [PDF]

, 2014
Robert Lowe, Vardhman K. Rakyan
openalex   +1 more source

Cannabis smoking is associated with persistent epigenome-wide disruptions despite smoking cessation. [PDF]

BMC Pulm Med
Cordero AIH, Li X, Yang CX, Ambalavanan A, MacIsaac JL, Kobor MS, Doiron D, Tan W, Bourbeau J, Sin DD, Duan Q, Leung JM, CanCOLD Collaborative Research Group.   +12 more
europepmc   +1 more source

Novel clinical trial designs emerging from the molecular reclassification of cancer

CA: A Cancer Journal for Clinicians, Volume 75, Issue 3, Page 243-267, May/June 2025.
Abstract Next‐generation sequencing has revealed the disruptive reality that advanced/metastatic cancers have complex and individually distinct genomic landscapes, necessitating a rethinking of treatment strategies and clinical trial designs. Indeed, the molecular reclassification of cancer suggests that it is the molecular underpinnings of the disease,
Mina Nikanjam, Shumei Kato, Teresa Allen, Jason K. Sicklick, Razelle Kurzrock   +4 more
wiley   +1 more source

Time for the epigenome [PDF]

Nature, 2010
openaire   +2 more sources

The Complex Epigenetic Panorama in the Multipartite Genome of the Nitrogen-Fixing Bacterium Sinorhizobium meliloti. [PDF]

Genome Biol Evol
Passeri I, Cangioli L, Fondi M, Mengoni A, Fagorzi C.   +4 more
europepmc   +1 more source