Results 261 to 270 of about 93,647 (322)

A Functional Approach to Testing Overall Effect of Interaction Between DNA Methylation and SNPs

Statistics in Medicine, Volume 45, Issue 1-2, January 2026.
ABSTRACT We introduce a test for the overall effect of interaction between DNA methylation and a set of single nucleotide polymorphisms on a quantitative phenotype. The developed inference procedure is based on a functional approach that extend existing regression models in functional data analysis.
Yvelin Gansou, Karim Oualkacha, Marzia Angela Cremona, Lajmi Lakhal‐Chaieb   +3 more
wiley   +1 more source

Epigenetic Mechanisms in Childhood Obesity. [PDF]

Ann N Y Acad Sci
León-Reyes G, González-Quijano GK, López-Alavez FJ, Tejero ME.   +3 more
europepmc   +1 more source

Supplemental Table 4 from Mitochondrial Uncoupling Induces Epigenome Remodeling and Promotes Differentiation in Neuroblastoma

Haowen Jiang, Rachel L. Greathouse, Sarah Jane Tiche, Man Zhao, Bo He, Yang Li, Albert M. Li, Balint Forgo, Michaela Yip, Allison Li, Moriah Shih, Selene Banuelos, Meng-Ning Zhou, Joshua J. Gruber, Erinn B. Rankin, Zhen Hu, Hiroyuki Shimada, Bill Chiu, Jiangbin Ye   +18 more
openalex   +1 more source

Enhancer Rewiring Orchestrates Inflammation and Loss of Cell Identity During Muscle Stem Cell Aging

Aging Cell, Volume 25, Issue 1, January 2026.
A comprehensive multi‐omic profiling of murine muscle stem cells across three ages and both sexes reveals extensive enhancer and 3D genome rewiring, concomitant with increased inflammation, lineage drift, loss of quiescence, and reduced myogenic potential.
Changyou Shi, Na Yang, Evelyn Pizano, Lin Wang, James R. Occean, Chang‐Yi Cui, Ling Liu, Christopher Dunn, Frimpong Boadu, Qiong Meng, Nirad Banskota, Jen‐Hao Yang, Jinshui Fan, Supriyo De, Jianlin Cheng, Thomas A. Rando, Vittorio Sartorelli, Payel Sen   +17 more
wiley   +1 more source

Epigenome-wide mediation analysis identified Cytosine-phosphate-Guanine sites linking environmental factors with diabetes indicators. [PDF]

Epigenomics
Lin WY.
europepmc   +1 more source

The Epigenome Network of Excellence

, 2005
Asifa Akhtar, Giacomo Cavalli
openalex   +2 more sources

Epigenetic Age Prediction Using N6‐Methyladenine in the Buff‐Tailed Bumblebee (Bombus terrestris)

Aging Cell, Volume 25, Issue 1, January 2026.
In bumblebees, age‐related patterns of N6‐methyladenine can be used to build accurate epigenetic clocks that are responsive to lifespan‐extending interventions, providing the first proof of concept that this epigenetic mark can be used as a biomarker of aging.
Thibaut Renard, Morgane Boseret, Serge Aron   +2 more
wiley   +1 more source

The Gut Microbiome and Epigenomic Reprogramming: Mechanisms, Interactions, and Implications for Human Health and Disease. [PDF]

Int J Mol Sci
Rubas NC, Torres A, Maunakea AK.
europepmc   +1 more source

Additional file 8: of Epigenome-wide skeletal muscle DNA methylation profiles at the background of distinct metabolic types and ryanodine receptor variation in pigs

, 2019
Siriluck Ponsuksili, Nares Trakooljul, Basavaraj Sajjanar, Frieder Hadlich, Eduard Muráni, Klaus Wimmers   +5 more
openalex   +1 more source

The Right Person, the Right Treatment, at the Right Time in Alzheimer's Disease: Insights From the 2025 Brain Aging Symposium

Aging Cell, Volume 25, Issue 1, January 2026.
The Brain Aging Symposium highlighted how early detection and longitudinal tracking, enabled by multimodal biomarker integration, reveal critical roles for lipid metabolism, sex differences, and population heterogeneity in improving diagnostic accuracy and timing of intervention.
Cecilia G. de Magalhães, Alibek Moldakozhayev, Maria Vina Lopez, Gene L. Bowman, Jasmeer P. Chhatwal, Manolis Kellis, Richard Mohs, Laura Nisenbaum, Yakeel T. Quiroz, Ravikiran M. Raju, Reisa A. Sperling, Mahdi Moqri, Vadim N. Gladyshev   +12 more
wiley   +1 more source