Results 261 to 270 of about 87,804 (313)

Potential multiple disease progression pathways in female patients with Alzheimer's disease inferred from transcriptome and epigenome data of the dorsolateral prefrontal cortex. [PDF]

PLoS One
Honda K, Awazu A.
europepmc   +1 more source

The Mutations and Their Relationships with the Genome and Epigenome, RNAs Editing and Evolution in Eukaryotes

, 2012
Daniel Frías-Lasserre
openalex   +2 more sources

Management of T‐cell malignancies: Bench‐to‐bedside targeting of epigenetic biology

CA: A Cancer Journal for Clinicians, Volume 75, Issue 4, Page 282-307, July/August 2025.
Abstract The peripheral T‐cell lymphomas (PTCL) are the only disease for which four histone deacetylase (HDAC) inhibitors have been approved globally as single agents. Although it is not clear why the PTCL exhibit such a vulnerability to these drugs, understanding the biological basis for this activity is essential.
Ariana Sabzevari, Johnson Ung, Jeffrey W. Craig, Kallesh D. Jayappa, Ipsita Pal, David J. Feith, Thomas P. Loughran Jr, Owen A. O’Connor   +7 more
wiley   +1 more source

Epigenomic signatures of accelerated epigenetic aging are associated with congenital heart disease in newborns. [PDF]

BMC Med Genomics
Kocher K, Ngwa J, Bhattacharya S, Donofrio M, Limperopoulos C, Andescavage N.   +5 more
europepmc   +1 more source

525 Epigenome-wide Association Study in the European Prospective Investigation Into Cancer and Nutrition (EPIC-Turin) Identifies Novel Genes Associated With Smoking

, 2012
Silvia Polidoro, Natalie Shenker, Karin van Veldhoven, Carlotta Sacerdote, Fulvio Ricceri, Rossana Critelli, Robert Brown, Paolo Vineis, James M. Flanagan   +8 more
openalex   +1 more source

CRISPRepi: a multi-omic atlas for CRISPR-based epigenome editing. [PDF]

Nucleic Acids Res
Shi L, Li S, Zhu R, Lu C, Xu X, Li C, Huang X, Zhao X, Mao F, Li K.   +9 more
europepmc   +1 more source

Antitumor efficacy of intermittent low‐dose erlotinib plus sulindac via MHC upregulation and remodeling of the immune cell niche

International Journal of Cancer, Volume 157, Issue 2, Page 355-370, 15 July 2025.
What's new? Novel immunomodulatory insights derived from experimental models and clinical samples reveal the cancer‐preventive potential of intermittent low‐dose erlotinib plus sulindac (ERL + SUL). This study shows that ERL + SUL treatment upregulates MHC class I and II expression and remodels the immune cell niche, with significant tumor suppression ...
Chakrapani Tripathi, Jorge E. Tovar Perez, Sabeeta Kapoor, Ahmed Muhsin, Wan Mohaiza Dashwood, Yunus Demirhan, Melek Demirhan, Alessandro Shapiro, Altaf Mohammed, Shizuko Sei, Jacklyn Thompson, Mahira Zaheer, Krishna M. Sinha, Powel H. Brown, Michelle I. Savage, Eduardo Vilar, Praveen Rajendran, Roderick H. Dashwood   +17 more
wiley   +1 more source

Sex-specific DNA methylation associations with circulating urate levels and BCG-induced urate changes. [PDF]

Commun Med (Lond)
Liu Z, Crișan TO, Qi C, Gupta MK, Liu X, Moorlag SJCFM, Koeken VACM, Jiang X, Ballan M, de Bree LCJ, Mourits VP, Gao X, Baccarelli A, Schwartz J, Pessler F, Guzmán CA, Li Y, Netea MG, Joosten LAB, Xu CJ.   +19 more
europepmc   +1 more source

An epigenome atlas of mouse adipocytes. [PDF]

Mol Metab
Hinte LC, Ghosh A, Castellano-Castillo D, Wolfrum C, von Meyenn F.   +4 more
europepmc   +1 more source

Development of a BiAD Sensor for Locus-Specific Detection of Cellular Histone Acetylation Dynamics by Fluorescence Microscopy. [PDF]

Genes (Basel)
Köhler AR, Gutekunst N, Harsch A, Bashtrykov P, Jeltsch A.   +4 more
europepmc   +1 more source