Results 321 to 328 of about 86,342 (328)
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2012
Epigenetic regulation is central to genome structure and function. Epigenetic status varies between individuals, and there is increasing awareness of the importance of this variation in health and disease. Epigenetic mechanisms include DNA methylation, histone modification, and regulation by noncoding RNAs.
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Epigenetic regulation is central to genome structure and function. Epigenetic status varies between individuals, and there is increasing awareness of the importance of this variation in health and disease. Epigenetic mechanisms include DNA methylation, histone modification, and regulation by noncoding RNAs.
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2010
Cancer is a heterogeneous disease caused largely by abnormalities of the genome and the epigenome. Typically, such abnormalities include genetic changes such as mutations and other genomic rearrangements or epigenetic changes such as aberrant DNA methylation and histone modifications that are frequently mediated by exposure to environmental or ...
Chris Boshoff +2 more
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Cancer is a heterogeneous disease caused largely by abnormalities of the genome and the epigenome. Typically, such abnormalities include genetic changes such as mutations and other genomic rearrangements or epigenetic changes such as aberrant DNA methylation and histone modifications that are frequently mediated by exposure to environmental or ...
Chris Boshoff +2 more
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2011
The development of male germ cells from the primordial germ cell stage to that of the mature spermatozoon is a key time of epigenetic reprogramming. Orchestrated by specialized enzymes, DNA methylation and histone modifications undergo dynamic changes throughout gametogenesis. Alterations to any level of the sperm epigenetic coding may affect fertility
Jacquetta M. Trasler, Donovan Chan
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The development of male germ cells from the primordial germ cell stage to that of the mature spermatozoon is a key time of epigenetic reprogramming. Orchestrated by specialized enzymes, DNA methylation and histone modifications undergo dynamic changes throughout gametogenesis. Alterations to any level of the sperm epigenetic coding may affect fertility
Jacquetta M. Trasler, Donovan Chan
openaire +2 more sources