Results 121 to 130 of about 33,317 (303)

Analyses of methylomes derived from Meso-American common bean (Phaseolus vulgaris L.) using MeDIP-seq and whole genome sodium bisulfite-sequencing

Frontiers in Plant Science, 2016
Common bean (Phaseolus vulgaris L.) is economically important for its high protein, fiber, and micronutrient contents, with a relatively small genome size of ~587 Mb. Common bean is genetically diverse with two major gene pools, Meso-American and Andean.
Mollee eCrampton, Venkateswara eSripathi, Khwaja eHossain, Venu (Kal) eKalavacharla   +3 more
doaj   +1 more source

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

Advanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang, Shaofang He, Zhongkai Wang, Aobo Pang, Xiaoli Sun, Rongchen Liu, Fang Wang, Sisi Chen, Zhijuan Bian, Dongcheng Wei, Liuhan Wu, Siyao Zhao, Qiuting Ji, Yiqi Sun, Niying Sun, Yushinta Fujaya, Boping Tang, Kianann Tan, Daizhen Zhang, Lianfu Chen   +19 more
wiley   +1 more source

Epigenetics and epigenomics studies in horticultural plants

Horticultural Plant Journal
Epigenetics and epigenomics have emerged as critical fields in plant biology, offering insights into the regulation of gene expression in plants in response to environmental stimuli without changes to the DNA sequence.
Huiru Liu, Chao Zhang, Yongbin Lu, Junzhang Li, Hang Yu, Haifeng Wang   +5 more
doaj   +1 more source

NAD+ Metabolism Licenses Zygotic Genome Activation via PARP7‐Mediated ADP‐Ribosylation of UHRF1 in Mouse Early Embryos

Advanced Science, EarlyView.
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao, Ziqi Zhang, Anqi Chen, Yanbo Liu, Yuling Lin, Lina Yu, Ruixin Shi, Aolei Guo, Yan Mao, Ganggui Lou, Chaojun Li, Luhong Wen, Guijun Yan, Haixiang Sun   +13 more
wiley   +1 more source

Advances in epigenetics and epigenomics in chronic lymphocytic leukemia

, 2019
Purpose of ReviewThe development and progression of chronic lymphocytic leukemia (CLL), a highly heterogenous B cell malignancy, are influenced by both genetic and environmental factors. Environmental factors, including pharmacological interventions, can
Xanthopoulos, Charalampos, Kostareli, Efterpi   +1 more
core   +1 more source

Advances in Gastric Cancer Research: Insights Into Carcinogenesis, the Tumor Microenvironment, Metastasis, and Factors Influencing Prognosis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background The Department of Gastroenterological Surgery at Kumamoto University has maintained a commitment to integrating cutting‐edge clinical practice with fundamental research, particularly concerning malignant diseases of the digestive tract.
Hideo Baba, Takatsugu Ishimoto, Yoshifumi Baba, Hiromitsu Hayashi, Masaaki Iwatsuki   +4 more
wiley   +1 more source

When Biology Meets Medicine: A Perspective on Foundation Models

Advanced Intelligent Discovery, EarlyView.
Artificial intelligence, and foundation models in particular, are transforming life sciences and medicine. This perspective reviews biological and medical foundation models across scales, highlighting key challenges in data availability, model evaluation, and architectural design.
Kunying Niu, Yuxing Wang, Limin Zou, Jing Huang   +3 more
wiley   +1 more source

Supplementary Figure Legend from Expanding Epigenomics to Archived FFPE Tissues: An Evaluation of DNA Repair Methodologies

, 2014
Supplementary Figure Legend from Expanding Epigenomics to Archived FFPE Tissues: An Evaluation of DNA Repair ...
Anders E. Berglund (698377), Abidemi O. Ajidahun (14971723), Domenico Coppola (53952), Steven A. Eschrich (9568968), Ryan M. Putney (11820185), David Shibata (114845), Erin M. Siegel (10104756), Bridget M. Riggs (14971720)   +7 more
core   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Related Article from Linking Epidemiology to Epigenomics—Where Are We Today?

, 2010
Related Article from Linking Epidemiology to Epigenomics—Where Are We ...
William M. Grady (13147411), Cornelia M. Ulrich (8542974)   +1 more
core   +1 more source