Results 141 to 150 of about 64,265 (410)
Perspectives on the Current and Future State of Artificial Intelligence in Medical Genetics
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Artificial intelligence (AI) is rapidly transforming numerous aspects of daily life, including clinical practice and biomedical research. In light of this rapid transformation, and in the context of medical genetics, we assembled a group of leaders in the field to respond to the question about how AI is affecting, and especially how AI will ...
Benjamin D. Solomon +20 more
wiley +1 more source
Nutritional Epigenomics and Age-Related Disease
Current Developments in Nutrition, 2020 Recent advances in epigenetic research have enabled the development of epigenetic clocks, which have greatly enhanced our ability to investigate molecular processes that contribute to aging and age-related disease. These biomarkers offer the potential to
S. Amenyah +7 more
semanticscholar +1 more source
Annals of Neurology, EarlyView.This final part 3 review builds on the practical applications discussed in part 2 and explores how artificial intelligence (AI) is transforming data management, neurological education, and neurological care across large healthcare networks and datasets. The review also highlights AI's role in real‐world and synthetic data, digital twins, and innovative
Matthew Rizzo
wiley +1 more source
Epigenetic treatment of solid tumours. A review of clinical trials [PDF]
, 2015 Epigenetic treatment has been approved by regulatory agencies for haematological malignancies. The success observe in cutaneous lymphomas represents a proof of principle that similar results may be obtained in solid tumours. Several agents that interfere
CODACCI PISANELLI, Giovanni +2 more
core +2 more sources
Animal Research and One Health, EarlyView.The experimental framework of the study encompasses sample collection, single‐cell data analysis, and experimental validation. Abstract Understanding differences in chromatin state and changes in gene regulatory landscape of placode (Pc) and dermal condensate are crucial for decoding hair follicle (HF) morphogenesis programs.
Fang Li +5 more
wiley +1 more source
Connecting high-resolution 3D chromatin organization with epigenomics
Nature Communications, 2020 The resolution of chromatin conformation capture technologies keeps increasing, and the recent nucleosome resolution chromatin contact maps allow us to explore how fine-scale 3D chromatin organization is related to epigenomic states in human cells. Using
Fan Feng +4 more
semanticscholar +1 more source
RSEA: A Web Server for Pathway Enrichment Analysis of Metabolic Reaction Sets
Biotechnology and Bioengineering, EarlyView.Reaction Set Enrichment Analysis (RSEA), a web server tool designed for metabolic pathway enrichment analysis of reaction sets derived from genome‐scale metabolic models was introduced. RSEA converts given reaction lists into standardized identifiers and statistically evaluates their enrichment across metabolic pathways.
Merve Yarıcı +4 more
wiley +1 more source
Long-read sequencing in the era of epigenomics and epitranscriptomics
Nature Methods, 2023 M. Lucas, E. Novoa
semanticscholar +1 more source
Epigenetics/Epigenomics and Prevention of Early Stages of Cancer by Isothiocyanates
Cancer Prevention Research, 2020 Cancer is a complex disease and cancer development takes 10–50 years involving epigenetics. Evidence suggests that approximately 80% of human cancers are linked to environmental factors impinging upon genetics/epigenetics.
Rasika R Hudlikar +10 more
semanticscholar +1 more source
DNA methylation profiling of the human major histocompatibility complex: A pilot study for the Human Epigenome Project [PDF]
, 2004 The Human Epigenome Project aims to identify, catalogue, and interpret genome-wide DNA methylation phenomena. Occurring naturally on cytosine bases at cytosine-guanine dinucleotides, DNA methylation is intimately involved in diverse biological processes ...
Andrews, TD +13 more
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