Results 161 to 170 of about 55,460 (328)

Epigenomic Modifications Predict Active Promoters and Gene Structure in Toxoplasma gondii

open access: gold, 2007
Mathieu Gissot   +4 more
openalex   +2 more sources

New trend in molecular diagnostics: Insights from the tumor microenvironment

open access: yesInterdisciplinary Medicine, EarlyView.
The graphical abstract outline the key elements in TME‐based molecular diagnostics, including biomarker exploration, diagnostic methods, and diagnostic models. Source: Created with BioRender.com. Abstract Molecular diagnosis has revolutionized cancer precision medicine.
Baiyuan Fan   +3 more
wiley   +1 more source

PB1808: EPIGENETIC INHIBITOR SCREEN TO IDENTIFY THERAPEUTIC CANDIDATES FOR MNX1-OVEREXPRESSING AML

open access: yesHemaSphere, 2023
Simge Kelekci   +13 more
doaj   +1 more source

Quercetin ameliorates lupus symptoms by promoting the apoptosis of senescent Tfh cells via the Bcl-2 pathway

open access: yesImmunity & Ageing
Systemic lupus erythematosus (SLE) is an autoimmune disorder that commonly affects the skin, kidneys, joints, and various other systemic tissues, with its development intricately linked to the process of immunosenescence.
Feng Xiong   +10 more
doaj   +1 more source

Bifenthrin Under Scrutiny: Revisiting Toxicological Evidence Amid Regulatory Gaps

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Despite growing health concerns, bifenthrin (BF) remains widely used for controlling agricultural and residential pests. However, different perspectives on its toxicological profile and regulatory framework warrant a revisit and update on BF regulation towards a robust risk‐safety assessment.
Caroline V. L. Moreira   +10 more
wiley   +1 more source

Combined and differential roles of ADD domains of DNMT3A and DNMT3L on DNA methylation landscapes in mouse germ cells

open access: yesNature Communications
DNA methyltransferase 3A (DNMT3A) and its catalytically inactive cofactor DNA methyltransferase 3-Like (DNMT3L) proteins form functional heterotetramers to deposit DNA methylation in mammalian germ cells.
Naoki Kubo   +5 more
doaj   +1 more source

Experimental approaches to the study of epigenomic dysregulation in ageing [PDF]

open access: green, 2010
Reid F. Thompson   +2 more
openalex   +1 more source

Cloud‐Based GWAS Platform: An Innovative Solution for Efficient Acquisition and Analysis of Genomic Data

open access: yesMed Research, EarlyView.
This graphical abstract illustrates the cloud‐based GWAS platform as a hub that integrates six major multiomics domains: phenomics, neuroscience, proteomics, microbiomics, metabolomics, and nutrigenomics. The platform unifies diverse data types—including clinical phenotypes, neuroimaging, plasma proteomics, microbiome profiles, metabolic biomarkers ...
Xiaohong Ke   +12 more
wiley   +1 more source

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