Results 211 to 220 of about 52,554 (369)

Multiomic Integration Analysis for Monitoring Severe Asthma Treated With Mepolizumab or Omalizumab

Allergy, EarlyView.
Mepolizumab and omalizumab induce a distinct clinical effect. Mepolizumab and omalizumab induce both common and treatment‐specific metabolic and protein profiles over time in patients with severe asthma. Multiomic integration and receiver operating characteristic curve analyses reveal a specific set of biomolecules suggesting their value as potential ...
Nuria Contreras, Andrea Escolar‐Peña, María I. Delgado‐Dolset, Paloma Fernández, David Obeso, Elena Izquierdo, Heleia González Cuervo, José Ángel Cumplido, Victoria Múgica, Carolina Cisneros, Santiago Angulo‐Díaz‐Parreño, Coral Barbas, Carlos Blanco, Teresa Carrillo, Domingo Barber, Alma Villaseñor, María M. Escribese   +16 more
wiley   +1 more source

Genomic technologies and the diagnosis of 46, XY differences of sex development

Andrology, EarlyView.
Abstract Differences/disorders of sex development can be caused by disruptions to the molecular and cellular mechanisms that control development and sex determination of the reproductive organs with 1:100 live births affected. Multiple genes are associated with 46, XY differences/disorders of sex development that can cause varying clinical phenotypes ...
Firman Idris, Andrew H. Sinclair, Katie L. Ayers   +2 more
wiley   +1 more source

Epigenomic insights into common disease [PDF]

, 2011
Kate Revill, Benjamin Tycko
openalex   +1 more source

Genocopy of EVI1‐AML with paraneoplastic diabetes insipidus: PRDM16 overexpression by t(1;2)(p36;p21) and enhancer hijacking

British Journal of Haematology, EarlyView.
Summary Diabetes insipidus (DI) in patients with acute myeloid leukaemia (AML) and chromosome 3q alterations (EVI1/PRDM3/MECOM overexpression) constitutes a poorly understood paraneoplasia. A 44‐year‐old patient presented with clinical and morphological features of this syndrome but, surprisingly, disclosed the rare translocation t(1;2)(p36;p21), with ...
Julian List, Etienne Sollier, Fiona Brown‐Burke, Katherine Kelly, Dietmar Pfeifer, Valeria Shlyakhto, Kristina Maas‐Bauer, Milena Pantic, Christoph Plass, Michael Lübbert   +9 more
wiley   +1 more source

Differential epigenomic and transcriptomic responses in subcutaneous adipose tissue between low and high responders to caloric restriction

, 2009
Luigi Bouchard, Rémi Rabasa‐Lhoret, May Faraj, Marie-Ève Lavoie, Jonathan Mill, Louis Pérusse, Marie‐Claude Vohl   +6 more
openalex   +1 more source

Breast Cancer Methylomes Establish an Epigenomic Foundation for Metastasis [PDF]

, 2011
Fang Fang, Şevin Turcan, Andreas Rimner, Andrew Kaufman, Dilip D. Giri, Luc G.T. Morris, Ronglai Shen, Venkatraman Seshan, Qianxing Mo, Adriana Heguy, Stephen B. Baylin, Nita Ahuja, Agnès Viale, Joan Massagué, Larry Norton, Linda T. Vahdat, Mary Ellen Moynahan, Timothy A. Chan   +17 more
openalex   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Environmental epigenomics and disease susceptibility [PDF]

, 2011
Michael K. Skinner
openalex   +1 more source

Three Synchronous Pituitary Neuroendocrine Tumors-Epigenomics Confirm an Exceptional Triple PitNET. [PDF]

Endocr Pathol
Rafiq T, Matschke J, Flitsch J, Dottermusch M.   +3 more
europepmc   +1 more source

Reversibility of sex changes in the plant kingdom: more important than we thought?

Biological Reviews, EarlyView.
ABSTRACT Compared to animals, plants show a wide range of reproductive strategies with different degrees of sex separation (e.g. dioecy, monoecy, hermaphroditism). While sex expression was previously thought to be genetically determined and fixed in plants, accumulating evidence suggests that sex expression can change reversibly even within one ...
Iris Sammarco, Eliška Krtilová, Marek Slovák, Clément Lafon Placette   +3 more
wiley   +1 more source