Results 211 to 220 of about 55,460 (328)

Integration of omics data in the diagnosis and therapy of glioblastoma

Brain Pathology, EarlyView.
Integration of omics data in the diagnosis and therapy of glioblastoma. Abstract Since the 2016 update of the WHO Classification of Tumors of the Central Nervous System, omics data have been officially integrated into the diagnostic process for glioblastoma, the most prevalent and aggressive primary malignant brain tumor in adults.
Constantin Möller, Melanie Schoof, Keith L. Ligon, Ulrich Schüller   +3 more
wiley   +1 more source

Identification of a distinct epigenetic subgroup with inferior PFS in intracranial mesenchymal tumors with FET::CREB fusion

Brain Pathology, EarlyView.
Six new cases of intracranial mesenchymal tumors with FET::CREB fusion, alongside 20 previously reported cases underwent DNA methylation profiling uncovered a novel epigenetic subgroup distinguished by inferior PFS and unique clinicopathological, molecular, and epigenetic hallmarks.
Yong Lin, Yun Ning, Yang Lan, Yu‐Juan Cao, Rui‐Jiao Zhao, Hai‐Nan Li, Song Duan, Wei‐Wei Fu, Hai‐Bo Wu, Feng Wu, Xiu‐Wu Bian, Tao Luo, Xiao‐Hong Yao   +12 more
wiley   +1 more source

Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold standard. [PDF]

Nucleic Acids Res
Lin YY, Breuer K, Weichenhan D, Lafrenz P, Sarnataro A, Wilk A, Chepeleva M, Mücke O, Schönung M, Petermann F, Kensche PR, Weiser L, Thommen F, Giacomelli G, Nordstroem K, Gonzalez-Avalos E, Merkel A, Kretzmer H, Fischer J, Krämer S, Iskar M, Wolf S, Buchhalter I, Esteller M, Lawerenz C, Twardziok S, Zapatka M, Hovestadt V, Schlesner M, Schulz MH, Hoffmann S, Gerhauser C, Walter J, Hartmann M, Lipka DB, Assenov Y, Bock C, Plass C, Toth R, Lutsik P.   +39 more
europepmc   +1 more source

News & Views in ... Epigenomics

, 2010

openalex   +1 more source

IDENTIFYING MASTER REGULATORS OF CANCER AND THEIR DOWNSTREAM TARGETS BY INTEGRATING GENOMIC AND EPIGENOMIC FEATURES [PDF]

, 2012
Olivier Gevaert, Sylvia K. Plevritis
openalex   +1 more source

Biopsia líquida: Un paso adelante en la medicina de laboratorio. [PDF]

Adv Lab Med
Díaz-Lagares A, Jiménez W.
europepmc   +1 more source

Integrating 5-Hydroxymethylcytosine into the Epigenomic Landscape of Human Embryonic Stem Cells

, 2011
Keith E. Szulwach, Xuekun Li, Yujing Li, Chun‐Xiao Song, Ji Woong Han, Sangsung Kim, Sandeep Namburi, Karen Hermetz, Julie J. Kim, M. Katharine Rudd, Young‐sup Yoon, Bing Ren, Chuan He, Peng Jin   +13 more
openalex   +2 more sources

EpiExplorer: live exploration and global analysis of large epigenomic datasets [PDF]

, 2012
Konstantin Halachev, Hannah Bast, Felipe Albrecht, Thomas Lengauer, Christoph Bock   +4 more
openalex   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Reversibility of sex changes in the plant kingdom: more important than we thought?

Biological Reviews, EarlyView.
ABSTRACT Compared to animals, plants show a wide range of reproductive strategies with different degrees of sex separation (e.g. dioecy, monoecy, hermaphroditism). While sex expression was previously thought to be genetically determined and fixed in plants, accumulating evidence suggests that sex expression can change reversibly even within one ...
Iris Sammarco, Eliška Krtilová, Marek Slovák, Clément Lafon Placette   +3 more
wiley   +1 more source