Results 1 to 10 of about 8,953 (240)
The total synthesis of D-chalcose and its C-3 epimer
Beilstein Journal of Organic Chemistry, 2013 We completed a new and efficient synthesis of D-chalcose (I) and the first synthesis of its C-3 epimer (I′) in nine steps with overall yields of 23% and 24%, respectively.
Jun Sun, Weige Zhang, Guoning Zhang
exaly +2 more sources
Marine Drugs, 2023 The fungal genus Meira was first reported in 2003 and has mostly been found on land. This is the first report of second metabolites from the marine-derived yeast-like fungus Meira sp.
Hee Jae Shin +3 more
doaj +1 more source
Epimers of Vitamin D: A Review [PDF]
International Journal of Molecular Sciences, 2020 In this review, we discuss the sources, formation, metabolism, function, biological activity, and potency of C3-epimers (epimers of vitamin D). We also determine the role of epimerase in vitamin D-binding protein (DBP) and vitamin D receptors (VDR) according to different subcellular localizations.
Bashar Al-Zohily +4 more
openaire +2 more sources
Investigation of the relationship between ergocristinine and vascular receptors
Toxicology Reports, 2023 Ergot alkaloids are secondary metabolites that exist in two configurations, the C-8-R-isomer (R-epimer), and the C-8-S-isomer (S-epimer). Toxic effects of ergot, such as vasoconstriction, have been primarily attributed to the R-epimer bioactivity, as ...
Jensen E. Cherewyk +2 more
doaj +1 more source
Stereoselective property of 20(S)-protopanaxadiol ocotillol type epimers affects its absorption and also the inhibition of P-glycoprotein. [PDF]
PLoS ONE, 2014 Stereoselectivity has been proved to be tightly related to drug action including pharmacodynamics and pharmacokinetics. (20S,24R)-epoxy-dammarane-3,12,25-triol (24R-epimer) and (20S,24S)-epoxy-dammarane-3,12,25-triol (24S-epimer), a pair of 20(S ...
Wenyan Wang +4 more
doaj +1 more source
The Impact of Storage Temperature and Time on Ergot Alkaloid Concentrations
Toxins, 2023 Ergot sclerotia produce toxic secondary metabolites, ergot alkaloids, that infect cereal crops and grasses. Ergot alkaloids have two isomeric configurations: the C-8-R-isomer (R-epimer), and the C-8-S-isomer (S-epimer).
Jensen E. Cherewyk +4 more
doaj +1 more source
Population Pharmacokinetics and Dosing Regimen Optimization of Latamoxef in Chinese Children
Pharmaceutics, 2022 The present study aimed to establish population pharmacokinetic models of latamoxef, as well as its R- and S-epimers, and generate findings to guide the individualized administration of latamoxef in pediatric patients. A total of 145 in-hospital children
Yang Wang +9 more
doaj +1 more source
Anti-Angiogenic Properties of Ginsenoside Rg3
Molecules, 2020 Ginsenoside Rg3 (Rg3) is a member of the ginsenoside family of chemicals extracted from Panax ginseng. Like other ginsenosides, Rg3 has two epimers: 20(S)-ginsenoside Rg3 (SRg3) and 20(R)-ginsenoside Rg3 (RRg3).
Maryam Nakhjavani +4 more
doaj +1 more source
Molecules, 2023 Hesperidin and narirutin are a class of flavanone glycosides, which are the main active constituents in Citrus reticulata Blanco. In the present study, a chiral HPLC-UV method with amylose tris(3,5-dimethylphenylcarbamate) as a stationary phase under a ...
Bingtong Jiang +3 more
doaj +1 more source
Epimerisation in Peptide Synthesis
Molecules, 2023 Epimerisation is basically a chemical conversion that includes the transformation of an epimer into another epimer or its chiral partner. Epimerisation of amino acid is a side reaction that sometimes happens during peptide synthesis.
Suleman Duengo +4 more
doaj +1 more source