Results 21 to 30 of about 8,953 (240)
Cytotoxic Isobractatin (Prenylated Xanthone) Epimer Mixture of Garcinia eugenifolia
In search of bioactive anti-cancer compounds from natural products has been found isobractatin from n-hexane extract of Garcinia eugenifolia. Isolation was done through the stages of maceration and column chromatography.
Sri Hartati +2 more
doaj +1 more source
State‐of‐the‐art synthesis of radiolabelled oligonucleotides involves multi‐step synthesis with high costs, extended timelines and significant radioactive waste generation. Herein, a dual‐methyltransferase platform enables late‐stage, site‐specific labelling, overcoming these limitations through reduced costs, faster turnaround and minimal radioactive ...
Christopher R. B. Swanson +3 more
wiley +2 more sources
An efficient radiosynthesis of fluorine‐18 labeled gluconic acid ([18F]FGA) was developed using two readily available materials, 2‐deoxy‐2‐[18F]fluoro‐D‐glucose ([18F]FDG) and glucose oxidase. [18F]FGA is highly specific for bacterial gluconate metabolism mediated by gluconate permease (GntP) and gluconate kinase (GntK), with rapid clearance, low off ...
Sang Hee Lee +7 more
wiley +2 more sources
Epimers vs. inverse epimers: the C-1 configuration in alnumycin A1
The determination of whether two stereoisomers constitute an epimeric pair or if they differ in their configuration at all stereogenic centers bar one can be deceptive, and even more problematic than just absolute configuration determination per se. The latter stereochemical relationship is hereby defined as a pair of inverse epimers and is exemplified
Petri Tähtinen +6 more
openaire +2 more sources
Glycyrrhizin (GA) analogs in the form of 3-glucuronides and 18-epimers were synthesized and their anticancer activities were evaluated. Alkaline isomerization of monoglucuronides is reported.
Yong-An Yang +5 more
doaj +1 more source
A New Languidulane Diterpenoid from Salvia mexicana var. mexicana
From the aerial parts of Salvia mexicana var. mexicana, two C-10 epimers (α and β) of salvimexicanolide were isolated. Our interpretation of the data, especially the 13C NMR, led us to conclude that the previously described 13C-NMR spectrum of the α ...
Jorge Cárdenas +5 more
doaj +1 more source
Because many therapeutic agents are contaminated by epimeric impurities or form epimers as a result of metabolism, analytical tools capable of determining epimers are increasingly in demand.
Chunsu Liang +7 more
doaj +1 more source
7--30-Methyloscillatoxin D From an Okinawan Cyanobacterium
Some aplysiatoxin-related compounds have been isolated from an Okinawan cyanobacterium Okeania hirsuta . The structure of a natural product isolated as 30-methyloscillatoxin D ( 1a ) from this cyanobacterium in our previous report was re-investigated and
Nao Kanda +8 more
doaj +1 more source
A Facile Synthesis of (±)-Heliannuol-D
A facile synthesis of (±)-heliannuol-D 1, which serves as an allelopathic chemical in nature and a potential lead compound in the search for new herbicides, has been achieved in a linear 11 steps, together with its epimer.
Tao Zhang +4 more
doaj +1 more source
Synthesis of Cyclophellitol Utilizing a Palladium Chloride Mediated-Ferrier-II Rearrangement
Cyclophellitol and its C3-epimer have been synthesized from5-enoglucopyranoside and 5-enomannopyranoside, respectively. The carbocyclic skeletonwas constructed through a Ferrier-II reaction meditated by PdCl2.
S. Ikegami, H. Takahashi
doaj +1 more source

