Results 21 to 30 of about 18,265 (273)

Lancifodilactone G : insights about an unusually stable enol [PDF]

open access: yes, 2008
From quantum mechanics calculations we confirm that the naturally occurring enol lancifodilactone G is stable over the keto form (by 2.6 kcal/mol in water), the only known stable aliphatic enol (devoid of conjugated or bulky aromatics and lacking a 1,3 ...
Chenoweth, D. M.   +2 more
core   +1 more source

Effects of Continuously Feeding Diets Containing Cereal Ergot Alkaloids on Nutrient Digestibility, Alkaloid Recovery in Feces, and Performance Traits of Ram Lambs

open access: yesToxins, 2017
Allowable limits for cereal ergot alkaloids in livestock feeds are being re-examined, and the objective of this study was to compare nutrient digestibility, growth performance and carcass characteristics of ram lambs fed a range of alkaloid ...
Stephanie Coufal-Majewski   +7 more
doaj   +1 more source

Uprolides N, O and P from the Panamanian Octocoral Eunicea succinea. [PDF]

open access: yes, 2016
Three new diterpenes, uprolide N (1), uprolide O (2), uprolide P (3) and a known one, dolabellane (4), were isolated from the CH₂Cl₂-MeOH extract of the gorgonian octocoral Eunicea succinea, collected from Bocas del Toro, on the Caribbean coast of Panama.
Fernandez, Patricia L   +7 more
core   +2 more sources

Ginsenoside Rg3: Potential Molecular Targets and Therapeutic Indication in Metastatic Breast Cancer

open access: yesMedicines, 2019
Breast cancer is still one of the most prevalent cancers and a leading cause of cancer death worldwide. The key challenge with cancer treatment is the choice of the best therapeutic agents with the least possible toxicities on the patient.
Maryam Nakhjavani   +6 more
doaj   +1 more source

Efficient routes to epimerically-pure side-chain derivatives of lanosterol [PDF]

open access: yes, 2004
A technically simple route is described to individual epimers of side-chain derivatives of lanosterol (3-hydroxy-5-lanosta-8,24-diene). Epimerically pure 24,25-epoxy-, 24,25-dihydroxy- and 24-bromo-25-hydroxy-lanosterol have been prepared in good yield ...
Kavtaradze, Levan K.   +2 more
core   +2 more sources

Stereoselective Anti-Cancer Activities of Ginsenoside Rg3 on Triple Negative Breast Cancer Cell Models

open access: yesPharmaceuticals, 2019
Ginsenoside Rg3 (Rg3) has two epimers, 20(S)-ginsenoside Rg3 (SRg3) and 20(R)-ginsenoside Rg3 (RRg3), and while Rg3 itself has been reported to have anti-cancer properties, few studies have been reported on the anti-cancer effects of the different ...
Maryam Nakhjavani   +8 more
doaj   +1 more source

Beyond Ribosomal Binding: The Increased Polarity and Aberrant Molecular Interactions of 3-epi-deoxynivalenol

open access: yesToxins, 2016
Deoxynivalenol (DON) is a secondary fungal metabolite and contaminant mycotoxin that is widely detected in wheat and corn products cultivated around the world.
Yousef I. Hassan   +3 more
doaj   +1 more source

Cytotoxic Isobractatin (Prenylated Xanthone) Epimer Mixture of Garcinia eugenifolia

open access: yesIndonesian Journal of Chemistry, 2014
In search of bioactive anti-cancer compounds from natural products has been found isobractatin from n-hexane extract of Garcinia eugenifolia. Isolation was done through the stages of maceration and column chromatography.
Sri Hartati   +2 more
doaj   +1 more source

Synthesis of 10b-fluorinated analogues of protubonine A and its 11a-epimer via fluorocyclisation of tryptophan-containing dipeptides [PDF]

open access: yes, 2015
Synthesis of 10b-fluorinated analogues of protubonine A and its 11a-epimer was accomplished using fluorocyclisation of tryptophan-containing dipeptides with N-fluoro-2,4,6-trimethylpyridinium triflate to 3a-fluoropyrrolo[2,3-b]indoles as a key step ...
Beniddir   +50 more
core   +2 more sources

Pd-catalyzed enantioselective aerobic oxidation of secondary alcohols: Applications to the total synthesis of alkaloids [PDF]

open access: yes, 2008
Enantioselective syntheses of the alkaloids (-)-aurantioclavine, (+)-amurensinine, (-)-lobeline, and (-)- and (+)-sedamine are described. The syntheses demonstrate the effectiveness of the Pd-catalyzed asymmetric oxidation of secondary alcohols in ...
Bagdanoff, Jeffrey T.   +5 more
core   +2 more sources

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