Results 121 to 130 of about 13,012 (246)
Ugi-Smiles Studies: Epimerization, Reduction and Polymer-Supported Reactions [PDF]
, 2017 The tandem Ugi-Smiles Intramolecular Diels-Alder (US-IMDA) reaction provides efficient assembly of diastereomeric epoxyisoindoline products through a one-pot multicomponent coupling.
Alabi, Philip
core
The FEBS Journal, EarlyView.Adult ascidians are capable of regenerating their entire brains following injury, and glycosaminoglycans have been shown to either promote or inhibit neuritogenesis. In this study, dermatan 2,6‐disulfate (D2,6S) was identified as the predominant complex carbohydrate in the ascidian brain.
Taynan Motta Portal +5 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 32, 3 August 2026.An enantioselective rhodium‐catalyzed [2 + 2 + 2] cycloaddition enables the synthesis of axially chiral diaryl ethers. Carbonyl coordination ensures high reactivity and regioselectivity, affording products bearing up to four stereogenic axes with good enantio‐ and diastereoselectivity.
Yu Sato +3 more
wiley +2 more sources
The FEBS Journal, EarlyView.Vitamin B6 is a critical molecule for plant metabolism and development. Rsr4‐1, a loss‐of‐function mutant in a vitamin B6 biosynthesis gene, has a distinct short root phenotype. Here we describe five novel suppressor mutants with an rsr4‐1 background that have normalized root growth and distinct phenotypic and molecular characteristics, representing a ...
Marcelina Parra +4 more
wiley +1 more source
Rapid Communications in Mass Spectrometry, Volume 40, Issue 20, 30 October 2026.ABSTRACT Rationale Liquid chromatography–tandem mass spectrometry (LC–MS/MS) analysis of vitamin D3 metabolites is analytically challenging because these compounds are structurally similar, strongly matrix‐associated, and have poor ionization efficiency.
Marzieh Amirmostofian +3 more
wiley +1 more source
Beraprost Attenuates Starvation‐Induced Apoptosis and Protects Feline Endothelial Cells
Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.This study established a feline endothelial cell starvation model to test the anti‐apoptotic effects of beraprost and its stereoisomers. Beraprost and beraprost‐314d reduced starvation‐induced apoptosis by inhibiting caspase‐3/7 activity and modulating Bax expression, while beraprost‐315d was less potent.
Takumi Matsuura +2 more
wiley +1 more source
Advanced Synthesis &Catalysis, Volume 368, Issue 16, 18 August 2026.A MgBr2‐catalyzed (3+2) cycloaddition between N‐thioacyl amidines and donor–acceptor cyclopropanes provides rapid access to 2‐amidino‐thiolanes in good yields and with high diastereoselectivities. The method displays broad substrate scope and offers an efficient route to sulfur‐containing amidine scaffolds of potential biological relevance.
Laurine Tual +4 more
wiley +1 more source
Actinomycin Derivatives: Structural Diversification and Biological Activities
ChemMedChem, Volume 21, Issue 15, 14 August 2026.Actinomycins are chromopeptide antibiotics exhibiting remarkable structural diversity and broad bioactivity. This review traces their development from naturally occurring D‐, X‐, A‐, G‐, Y‐, and Z‐type analogs to precursor‐directed, synthetic, and semisynthetic derivatives.
Özge Can, Erdal Bedir
wiley +1 more source
Improved Incorporation of Arylglycines Into Ramoplanin Sequences via Solid‐Phase Peptide Synthesis
European Journal of Organic Chemistry, Volume 29, Issue 30, 12 August 2026.The incorporation of arylglycines using solid‐phase peptide synthesis remains challenging due to the sensitivity of these residues for epimerization. Here, exploring multiple conditions for the incorporation of arylglycine residues into peptides using SPPS demonstrates how small changes to current synthesis protocols can lead to significant ...
Edward Marschall +3 more
wiley +1 more source