Carcinogenic and anticancer activities of microbiota-derived secondary bile acids [PDF]
Frontiers in OncologySecondary bile acids (SBAs), which are metabolites produced by gut microbiota, have been implicated in both carcinogenic and anticancer processes. This review explores the dual role of SBAs, focusing on their molecular mechanisms and biological effects ...
Mobina Kouhzad +7 more
doaj +6 more sources
Specific Secondary Bile Acids Control Chicken Necrotic Enteritis [PDF]
Pathogens, 2021 Necrotic enteritis (NE), mainly induced by the pathogens of Clostridium perfringens and coccidia, causes huge economic losses with limited intervention options in the poultry industry.
Mohit Bansal +9 more
doaj +7 more sources
Phenotyping the Chemical Communications of the Intestinal Microbiota and the Host: Secondary Bile Acids as Postbiotics [PDF]
CellsThe current definition of a postbiotic is a “preparation of inanimate microorganisms and/or their components that confers a health benefit on the host”.
Ginevra Urbani +5 more
doaj +4 more sources
Secondary Bile Acids and Tumorigenesis in Colorectal Cancer [PDF]
Frontiers in Oncology, 2022 Colorectal cancer (CRC) is one of the most common and deadly cancers in the world and is a typical inflammatory tumor. In recent years, the incidence of CRC has been increasing year by year. There is evidence that the intake of high-fat diet and overweight are associated with the incidence of CRC, among which bile acids play a key role in the ...
Guang Ji, Shengan Zhang, Hanchen Xu
exaly +5 more sources
Disease-Associated Gut Microbiota Reduces the Profile of Secondary Bile Acids in Pediatric Nonalcoholic Fatty Liver Disease [PDF]
Frontiers in Cellular and Infection Microbiology, 2021 Children with nonalcoholic fatty liver disease (NAFLD) display an altered gut microbiota compared with healthy children. However, little is known about the fecal bile acid profiles and their association with gut microbiota dysbiosis in pediatric NAFLD. A
Jiake Yu +5 more
doaj +2 more sources
Investigation of bile salt hydrolase activity in human gut bacteria reveals production of conjugated secondary bile acids [PDF]
Nature CommunicationsThrough biochemical transformation of host-derived bile acids, gut bacteria mediate host-microbe crosstalk and function at the interface of nutrition and host metabolic regulation.
Lauren N. Lucas +10 more
doaj +2 more sources
The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice [PDF]
Gut Microbes, 2021 Extibacter muris is a newly described mouse gut bacterium which metabolizes cholic acid (CA) to deoxycholic acid (DCA) via 7α-dehydroxylation. Although bile acids influence metabolic and inflammatory responses, few in vivo models exist for studying their
Theresa Streidl +20 more
doaj +2 more sources
Amelioration of Colitis by a Gut Bacterial Consortium Producing Anti-Inflammatory Secondary Bile Acids [PDF]
Microbiology Spectrum, 2023 Lei Dai
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Isomaltulose Exhibits Prebiotic Activity, and Modulates Gut Microbiota, the Production of Short Chain Fatty Acids, and Secondary Bile Acids in Rats [PDF]
Molecules, 2021 Fei Peng, Hui-Hui Su, Ri-Yi Xu
exaly +2 more sources
Secondary bile acids improve risk prediction for non‐invasive identification of mild liver fibrosis in nonalcoholic fatty liver disease [PDF]
Alimentary Pharmacology and Therapeutics, 2023 Giovanni Targher +2 more
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