Results 31 to 40 of about 60,836 (146)

Consortium of Probiotics Attenuates Colonization of Clostridioides difficile

Frontiers in Microbiology, 2019
Clostridioides difficile infection (CDI) is increasing morbidity and mortality rates globally. Fecal microbiota transplantation (FMT), an effective therapy for eliminating Clostridioides difficile (C.
Xianping Li, Xianping Li, Qiongfang Chu, Qiongfang Chu, Qiongfang Chu, Yuanming Huang, Yuanming Huang, Yuchun Xiao, Yuchun Xiao, Liqiong Song, Liqiong Song, Siyi Zhu, Siyi Zhu, Ying Kang, Ying Kang, Shan Lu, Shan Lu, Jianguo Xu, Jianguo Xu, Zhihong Ren, Zhihong Ren   +20 more
doaj   +1 more source

Role of primary and secondary bile acids as feedback inhibitors of bile acid synthesis in the rat in vivo. [PDF]

Journal of Clinical Investigation, 1989
The effect of various primary and secondary bile acids on the rates of synthesis of all major bile acids was studied in the live rat with an extracorporal bile duct. Bile acid synthesis was determined using HPLC based on mass or by isotope dilution. Derepressed rates of bile acid synthesis (30-54 h) were inhibited by an infusion of taurocholic acid ...
E F, Stange, J, Scheibner, H, Ditschuneit   +2 more
openaire   +2 more sources

Secondary bile acids are associated with body lipid accumulation in obese pigs. [PDF]

Anim Nutr
The aim of this study was to investigate the reasons for the differences in lipid accumulation between lean and obese pigs. The bile acids with varying levels within two types of pigs were found and then in vitro experiments were conducted to identify whether these bile acids can directly affect lipid accumulation.
Hu Y, Wu A, Yan H, Pu J, Luo J, Zheng P, Luo Y, Yu J, He J, Yu B, Chen D.   +10 more
europepmc   +4 more sources

Colonic inflammation and secondary bile acids in alcoholic cirrhosis

American Journal of Physiology-Gastrointestinal and Liver Physiology, 2014
Alcohol abuse with/without cirrhosis is associated with an impaired gut barrier and inflammation. Gut microbiota can transform primary bile acids (BA) to secondary BAs, which can adversely impact the gut barrier. The purpose of this study was to define the effect of active alcohol intake on fecal BA levels and ileal and colonic inflammation in ...
Genta, Kakiyama, Phillip B, Hylemon, Huiping, Zhou, William M, Pandak, Douglas M, Heuman, Dae Joong, Kang, Hajime, Takei, Hiroshi, Nittono, Jason M, Ridlon, Michael, Fuchs, Emily C, Gurley, Yun, Wang, Runping, Liu, Arun J, Sanyal, Patrick M, Gillevet, Jasmohan S, Bajaj   +15 more
openaire   +3 more sources

Manipulating the Microbiome: An Alternative Treatment for Bile Acid Diarrhoea

Microbiology Research, 2021
Bile acid diarrhoea (BAD) is a widespread gastrointestinal disease that is often misdiagnosed as irritable bowel syndrome and is estimated to affect 1% of the United Kingdom (UK) population alone.
Evette B. M. Hillman, Sjoerd Rijpkema, Danielle Carson, Ramesh P. Arasaradnam, Elizabeth M. H. Wellington, Gregory C. A. Amos   +5 more
doaj   +1 more source

Bile acids are a risk factor for colorectal cancer [PDF]

Терапевтический архив, 2020
Bile acids were first considered carcinogenic in 1939. Since then, accumulated data have associated colon cell changes with high levels of bile acids as an important risk factor for developing colorectal cancer, which is more common among people who ...
L. M. Krumz, R. B. Gudkova, L. Kh. Indejkina, E. A. Sabelnikova, A. I. Parfenov   +4 more
doaj   +1 more source

A secondary bile acid from microbiota metabolism attenuates ileitis and bile acid reduction in subclinical necrotic enteritis in chickens [PDF]

Journal of Animal Science and Biotechnology, 2020
Abstract Background Clostridium perfringens-induced chicken necrotic enteritis (NE) is responsible for substantial economic losses worldwide annually. Recently, as a result of antibiotic growth promoter prohibition, the prevalence of NE in chickens has reemerged.
Mohit Bansal, Ying Fu, Bilal Alrubaye, Mussie Abraha, Ayidh Almansour, Anamika Gupta, Rohana Liyanage, Hong Wang, Billy Hargis, Xiaolun Sun   +9 more
openaire   +3 more sources

The role of serum bile acid profile in differentiation between nonalcoholic fatty liver disease and chronic viral hepatitis

Egyptian Liver Journal, 2020
Background Bile acids are essential organic molecules synthesized from cholesterol in the liver. They have been utilized as indicators of hepatobiliary impairment because synthesis of BAs and their metabolism are influenced by liver diseases. We aimed to
Azza Elsheashaey, Manar Obada, Eman Abdelsameea, Mohamed F. F. Bayomy, Hala El-Said   +4 more
doaj   +1 more source

Bile Acid Metabolome after an Oral Lipid Tolerance Test by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS). [PDF]

PLoS ONE, 2016
Besides their role in intestinal resorption of lipids, bile acids are regarded as endocrine and metabolic signaling molecules. The detailed profile of bile acid species in peripheral blood after an oral lipid tolerance test (OLTT) is unknown.We ...
Andreas Schmid, Hannah Neumann, Thomas Karrasch, Gerhard Liebisch, Andreas Schäffler   +4 more
doaj   +1 more source

Dominant Bacterial Phyla from the Human Gut Show Widespread Ability To Transform and Conjugate Bile Acids

mSystems, 2021
Gut bacteria influence human physiology by chemically modifying host-synthesized primary bile acids. These modified bile acids, known as secondary bile acids, can act as signaling molecules that modulate host lipid, glucose, and energy metabolism and ...
L. N. Lucas, K. Barrett, R. L. Kerby, Q. Zhang, L. E. Cattaneo, D. Stevenson, F. E. Rey, D. Amador-Noguez   +7 more
doaj   +1 more source