Results 51 to 60 of about 60,836 (146)
Shipin yu jixieObjectiveThis study aimed to investigate the effects of an acidic tea polysaccharide extracted from Wuyi Rock tea "yellow slice" on bile acids in hyperglycaemic rats.MethodsIn vitro experiments simulating artificial gastric and intestinal fluids were ...
WU Zhong, YANG Jiangfan
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Letter: bile acid diarrhoea is not a rare cause of diarrhoea in secondary care [PDF]
Alimentary Pharmacology & Therapeutics, 2014 SIRS, We read the article by Wilcox et al., and the letter by Kurien et al. with interest. We agree that bile acid diarrhoea (BAD) may be the underlying aetiology in a significant proportion of patients with chronic diarrhoea. With this in mind, we would like to share our own experience of this issue. We undertook a review of consecutive unselected new
U N, Shivaji, F U, Chowdhury, A C, Ford
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Bile Acids, Intestinal Barrier Dysfunction, and Related Diseases
Cells, 2023 The intestinal barrier is a precisely regulated semi-permeable physiological structure that absorbs nutrients and protects the internal environment from infiltration of pathological molecules and microorganisms. Bile acids are small molecules synthesized
Linsen Shi, Lihua Jin, Wendong Huang
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Secondary Unconjugated Bile Acids Induce Hepatic Stellate Cell Activation [PDF]
International Journal of Molecular Sciences, 2018 Hepatic stellate cells (HSCs) are key players in liver fibrosis, cellular senescence, and hepatic carcinogenesis. Bile acids (BAs) are involved in the activation of HSCs, but the detailed mechanism of this process remains unclear. We conducted a comprehensive DNA microarray study of the human HSC line LX-2 treated with deoxycholic acid (DCA), a ...
Kunihiro Saga +13 more
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mBioBile acids play a critical role in the emulsification of dietary lipids, a critical step in the primary function of the small intestine, which is the digestion and absorption of food.
Jenni Firrman +7 more
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Metagenomic analysis of bile salt biotransformation in the human gut microbiome
BMC Genomics, 2019 Background In the biochemical milieu of human colon, bile acids act as signaling mediators between the host and its gut microbiota. Biotransformation of primary to secondary bile acids have been known to be involved in the immune regulation of human ...
Promi Das +3 more
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In vitro and in vivo characterization of Clostridium scindens bile acid transformations
Gut Microbes, 2019 The human gut hosts trillions of microorganisms that exert a profound influence on human biology. Gut bacteria communicate with their host by secreting small molecules that can signal to distant organs in the body.
Solenne Marion +7 more
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Deoxycholic Acid, a Secondary Bile Acid, Increases Cardiac Output and Blood Pressure in Rats
Nutrients, 2023 Background: Deoxycholic acid (DCA) is a secondary bile acid produced by gut bacteria. Elevated serum concentrations of DCA are observed in cardiovascular disease (CVD). We hypothesized that DCA might influence hemodynamic parameters in rats. Methods: The concentration of DCA in systemic blood was measured with liquid chromatography coupled with mass ...
Artur Nowiński +4 more
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Conjugated bile acids are elevated in severe calcific aortic valve stenosis
Journal of Lipid ResearchCalcific aortic valve (AV) stenosis (CAVS) is a disease associated with significant morbidity and mortality in the aging population. Recently, bile acids have been shown to play a significant role in many disease processes, and untargeted metabolomic ...
Hannah Zhang +7 more
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Critical roles of bile acids in regulating intestinal mucosal immune responses
Therapeutic Advances in Gastroenterology, 2021 Bile acids are a class of cholesterol derivatives that have been known for a long time for their critical roles in facilitating the digestion and absorption of lipid from the daily diet.
Ruicong Sun +4 more
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