Results 61 to 70 of about 13,012 (246)

Isoleucine epimerization in Quarternary planktic foraminifera of sediment core GIK12519-2, Sierra Leone Rise [PDF]

, 1984
Panktonic foraminiferal tests of the spinose species Orbulina universa, of the non-spinose Globorotalia tumida-menardii complex, and of a mixed species assemblage (grain size fraction 200-400 µm) were isolated from Sierra Leone Rise core GIK13519-2 and ...
Peter J Müller (6959537), Müller, Peter J   +1 more
core   +1 more source

A macrolactonization approach to the total synthesis of the antimicrobial cyclic depsipeptide LI-F04a and diastereoisomeric analogues

Beilstein Journal of Organic Chemistry, 2012
The cyclic peptide core of the antifungal and antibiotic cyclic depsipeptide LI-F04a was synthesised by using a modified Yamaguchi macrolactonization approach.
James R. Cochrane, Dong Hee Yoon, Christopher S. P. McErlean, Katrina A. Jolliffe   +3 more
doaj   +1 more source

Tailored Covalent Organic Frameworks Enable the Encapsulation of Living Cells to Produce Rare Ginsenoside

Advanced Science, EarlyView.
This work reports the in situ fabrication of Escherichia coli@covalent organic frameworks (E. coli@COFs) in phosphate‐buffered saline. The COFs form an exoskeleton on E. coli, protecting intracellular β‐glucosidase (Ssbgl) while enhancing mass transfer.
Fengmei Liu, Shan Zhang, Shanrong Wei, Ziye Xing, Hongming He, Xiao Liang, Quanshun Li   +6 more
wiley   +1 more source

The unusual bifunctional catalysis of epimerization and desaturation by carbapenem synthase. [PDF]

, 2004
High-level ab initio calculations have been used to study the mechanism for the conversion of (3S,5S)-carbapenam to the biologically active beta-lactam antibiotic, (5R)-carbapenem, catalyzed by carbapenem synthase.
Topf, M, Sandala, GM, Easton, CJ, Radom, L, Schofield, CJ, Schofield, Christopher, Smith, DM   +6 more
core   +1 more source

Epimerization-free C-terminal peptide activation, elongation and cyclization [PDF]

, 2015
C-terminal peptide activation and cyclization reactions are generally accompanied with epimerization (partial loss of C‐terminal stereointegrity). Therefore, the focus of this thesis was to develop epimerization-free methods for C-terminal peptide ...
Popović, S.
core   +3 more sources

Preparation of Chiral Enantioenriched Densely Substituted Cyclopropyl Azoles, Amines, and Ethers via Formal S_N2′ Substitution of Bromocylopropanes

Molecules, 2022
Enantiomerically enriched cyclopropyl ethers, amines, and cyclopropylazole derivatives possessing three stereogenic carbon atoms in a small cycle are obtained via the diastereoselective, formal nucleophilic substitution of chiral, non-racemic ...
Hillary Straub, Pavel Ryabchuk, Marina Rubina, Michael Rubin   +3 more
doaj   +1 more source

epimerization

, 2014
Citation: 'epimerization' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.E02166 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial
openaire   +1 more source

Synthetic investigations in epimerization reactions of β-lactams [PDF]

, 2022
A novel and facile synthesis of cis-3-phenylthio & cis-3-chloro-β-lactams using epimerization reaction has been studied. The optimized reaction conditions for this conversion using very mild base have been studied.
Thapar, Renu ; University Institute of Engineering and Technology (U.I.E.T), Panjab University, Sector-25, Chandigarh-160 014, India, Thakur, Aarti ; University Institute of Engineering and Technology (U.I.E.T), Panjab University, Sector-25, Chandigarh-160 014, India Department of Chemistry & Centre of Advanced Studies in Chemistry, Panjab University, Sector-14, Chandigarh-160 014, India, Pandey, Suvidha ; Department of Chemistry & Centre of Advanced Studies in Chemistry, Panjab University, Sector-14, Chandigarh-160 014, India   +2 more
core   +2 more sources

Oxepinamide F biosynthesis involves enzymatic d-aminoacyl epimerization, 3H-oxepin formation, and hydroxylation induced double bond migration

Nature Communications, 2020
Oxepinamides are a class of fungal oxepins with biological activities. Here, the authors elucidate the biosynthetic pathway of oxepinamide F from Aspergillus ustus and show that it involves enyme-catalysed oxepin ring formation, hydroxylation-induced ...
Liujuan Zheng, Haowen Wang, Aili Fan, Shu-Ming Li   +3 more
doaj   +1 more source

Rational modification of substrate binding site by structure-based engineering of a cellobiose 2-epimerase in Caldicellulosiruptor saccharolyticus

Microbial Cell Factories, 2017
Background Lactulose, a synthetic disaccharide, has received increasing interest due to its role as a prebiotic, specifically proliferating Bifidobacilli and Lactobacilli and enhancing absorption of calcium and magnesium.
Ah-Reum Park, Jin-Sook Kim, Seung-Won Jang, Young-Gyun Park, Bong-Seong Koo, Hyeon-Cheol Lee   +5 more
doaj   +1 more source