Results 71 to 80 of about 7,269 (167)
The PRRT2 knockout mouse recapitulates the neurological diseases associated with PRRT2 mutations
Neurobiology of Disease, 2017 Heterozygous and rare homozygous mutations in PRoline-Rich Transmembrane protein 2 (PRRT2) underlie a group of paroxysmal disorders including epilepsy, kinesigenic dyskinesia episodic ataxia and migraine.
Caterina Michetti +11 more
doaj +1 more source
Urodynamic Voiding Patterns in Multiple Sclerosis
Neurourology and Urodynamics, EarlyView.ABSTRACT Aims This study aimed to describe urodynamic voiding patterns in patients with MS (PwMS) using standardized assessments, and to compare the performance of the available nomograms and indices for obstruction and bladder contractility. Methods PwMS and lower urinary tract symptoms underwent cystometry and pressure flow studies.
Camille Chesnel +5 more
wiley +1 more source
α‐Synuclein strain homogeneity in multiple system atrophy subtypes
Brain Pathology, EarlyView.Two different subtypes of multiple system atrophy are recognized: MSA‐C and MSA‐P. In this manuscript, Lau et al. investigate whether MSA‐C and MSA‐P are caused by different strains of α‐synuclein aggregates. By performing conformational fingerprinting experiments as well as in vitro and in vivo seeding assays, their findings suggest that both MSA‐C ...
Heather H. C. Lau +10 more
wiley +1 more source
Cancer pain: current practice and emerging targets
British Journal of Pharmacology, EarlyView.Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
Inborn errors of immunity in children with neuroinflammation
Developmental Medicine &Child Neurology, EarlyView.Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu +5 more
wiley +1 more source
Review: Current treatment of vestibular, ocular motor disorders and nystagmus
Therapeutic Advances in Neurological Disorders, 2009 Vertigo and dizziness are among the most common complaints with a lifetime prevalence of about 30%. The various forms of vestibular disorders can be treated with pharmacological therapy, physical therapy, psychotherapeutic measures or, rarely, surgery ...
Michael Strupp, Thomas Brandt
doaj +1 more source
Developmental Medicine &Child Neurology, EarlyView.xxxxxx Aim To systematically review the effectiveness, safety, and economic evidence of pharmacological and non‐pharmacological interventions for sleep disorders in children with cerebral palsy (CP). Method Databases including MEDLINE, Embase, CENTRAL (the Cochrane Library), International Clinical Trials Registry Platform of the World Health ...
Nishant Jaiswal +11 more
wiley +1 more source
Vertical Saccadic Slowing in Episodic Ataxia Type 2. [PDF]
J Clin Neurol, 2022 Kim S, Kim S, Lee S, Kim HJ.
europepmc +1 more source
Developmental Medicine &Child Neurology, EarlyView.This study characterized 519 children and adolescents with vertigo using clinical, diagnostic, imaging, quality‐of‐life, and demographic data, identifying vestibular migraine as the most frequent diagnosis, followed by functional dizziness and recurrent vertigo of childhood.
Doreen Huppert +7 more
wiley +1 more source
Episodic ataxia type 2 (EA2) with interictal myokymia and focal dystonia. [PDF]
Cold Spring Harb Mol Case Stud, 2022 Nielsen EN +4 more
europepmc +1 more source