Results 91 to 100 of about 2,663,291 (229)
Lettuce Genetics: Inheritance, Linkage, and Epistasis [PDF]
Journal of the American Society for Horticultural Science, 1992 Two new lettuce (Luctuca sativa L.) genes are described and named truncated leaf (tn), and sickly (si). A gene for reflexed involucre is identical to that previously described in wild lettuce (L. serriola L.). Mosaic reaction (me) and light green (lg) are linked, with P = 0.448. Six gene pairs tested for linkage are independently inherited.
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EPISTASIS BETWEEN NEW MUTATIONS AND GENETIC BACKGROUND AND A TEST OF GENETIC CANALIZATION [PDF]
Evolution, 2001 The importance for fitness of epistatic interactions among mutations is poorly known, yet epistasis can exert important effects on the dynamics of evolving populations. We showed previously that epistatic interactions are common between pairs of random insertion mutations in the bacterium Escherichia coli. In this paper, we examine interactions between
Richard E. Lenski, Santiago F. Elena
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ChemSusChem, EarlyView.Utilizing the power of the absorbance‐activated droplet sorter, a key enzyme for a cell‐free multienzymatic cascade for sustainable isobutanol biosynthesis is optimized for improved thermostability and isobutanol tolerance required for efficient cascade performance.
Mariko Teshima +6 more
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Molecular Systems Biology, 2015 Cancers, like many diseases, are normally caused by combinations of genetic alterations rather than by changes affecting single genes. It is well established that the genetic alterations that drive cancer often interact epistatically, having greater or ...
Solip Park, Ben Lehner
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Dominance, epistasis, heritabilities and expected genetic gains [PDF]
Genetics and Molecular Biology, 2005 Although epistasis is common in gene systems that determine quantitative traits, it is usually not possible to estimate the epistatic components of genotypic variance because experiments in breeding programs include only one type of progeny. As the study of this phenomenon is complex, there is a lack of theoretical knowledge on the contribution of the ...
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Genetic epistasis regulates amyloid deposition in resilient aging [PDF]
Alzheimer's & Dementia, 2017 AbstractIntroductionThe brain‐derived neurotrophic factor (BDNF) interacts with important genetic Alzheimer's disease (AD) risk factors. Specifically, variants within the SORL1 gene determine BDNF's ability to reduce amyloid β (Aβ) in vitro. We sought to test whether functional BDNF variation interacts with SORL1 genotypes to influence expression and ...
Lori B. Chibnik +15 more
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BMC Genetics, 2006 Background A genetic model about quantitative trait loci (QTL) provides a basis to interpret the genetic basis of quantitative traits in a study population, such as additive, dominance and epistatic effects of QTL and the partition of genetic variance ...
Wang Tao, Zeng Zhao-Bang
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Lower-order effects adjustment in quantitative traits model-based multifactor dimensionality reduction. [PDF]
PLoS ONE, 2012 Identifying gene-gene interactions or gene-environment interactions in studies of human complex diseases remains a big challenge in genetic epidemiology.
Jestinah M Mahachie John +4 more
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PLANTS, PEOPLE, PLANET, EarlyView.Plant breeding is a critical tool for increasing the productivity, climate resilience, and sustainability of agriculture, but current phenotyping methods are a bottleneck due to the amount of human labor involved. Here, we demonstrate high‐throughput phenotyping with an unmanned aerial vehicle (UAV) to analyze the season‐long flowering pattern in ...
Jeevan Adhikari +5 more
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BMC Genomics, 2008 Background The difficulty in elucidating the genetic basis of complex diseases roots in the many factors that can affect the development of a disease.
Galan Jose +10 more
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