Results 31 to 40 of about 49,240 (217)
The effect of epistasis on sexually antagonistic genetic variation [PDF]
Proceedings of the Royal Society B: Biological Sciences, 2014 There is increasing evidence of segregating sexually antagonistic (SA) genetic variation for fitness in laboratory and wild populations, yet the conditions for the maintenance of such variation can be restrictive. Epistatic interactions between genes can contribute to the maintenance of genetic variance in fitness and we suggest that epistasis between ...
G. Arnqvist, N. Vellnow, L. Rowe
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Statistical Modeling of Epistasis and Linkage Decay using Logic Regression [PDF]
, 2008 Logic regression has been recognized as a tool that can identify and model non-additive genetic interactions using Boolean logic groups. Logic regression, TASSEL-GLM and SAS-GLM were compared for analytical precision using a previously characterized ...
Jean-Luc Jannink +4 more
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Genetic Dissection of Cytonuclear Epistasis in Line Crosses [PDF]
Genetics, 2007 Abstract Dissection of cytonuclear interactions is fundamentally important for understanding the genetic architecture of complex traits. Here we propose a mating design based on reciprocal crosses and extend the existing QTL mapping method to evaluate the contribution of cytoplasm and QTL × cytoplasm interactions to the phenotypic ...
Zefeng Yang +4 more
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Exploring the effect of sex on empirical fitness landscapes [PDF]
, 2009 The nature of epistasis has important consequences for the evolutionary significance of sex and recombination. Recent efforts to find negative epistasis as a source of negative linkage disequilibrium and associated long-term advantage to sex have yielded
Krug, J. +2 more
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Functional Regression Models for Epistasis Analysis of Multiple Quantitative Traits.
PLoS Genetics, 2016 To date, most genetic analyses of phenotypes have focused on analyzing single traits or analyzing each phenotype independently. However, joint epistasis analysis of multiple complementary traits will increase statistical power and improve our ...
Futao Zhang +4 more
doaj +1 more source
Influence of epistasis on response to genomic selection using complete sequence data
Genetics Selection Evolution, 2017 Background The effect of epistasis on response to selection is a highly debated topic. Here, we investigated the impact of epistasis on response to sequence-based selection via genomic best linear prediction (GBLUP) in a regime of strong non-symmetrical ...
Natalia S. Forneris +3 more
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The Indian Journal of Agricultural Sciences, 2021 To estimate epistasis and components of genetic variance a study was carried out during 2016 and 2017 at Experimental Research Farm of Department of Vegetable Science, Dr YSP UH & F Nauni, Solan, (HP) and data were recorded for different qualitative and
REENA KUMARI, RAMESH KUMAR, MEENU GUPTA
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BMC Genomics, 2022 Background The influence of linkage disequilibrium (LD), epistasis, and inbreeding on genotypic variance continues to be an important area of investigation in genetics and evolution.
José Marcelo Soriano Viana +1 more
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Evidence of epistasis between Interleukin-1 and Selenoprotein-S with susceptibility to rheumatoid arthritis [PDF]
, 2009 Objective: Selenoprotein-S (SELS) is involved in the stress response within the endoplasmic reticulum (ER) and inflammation. Recently, promoter variants in the SELS gene were shown to be associated with plasma levels of interleukin (IL)6, IL1β and tumour
Binks, M.H. +5 more
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Enhancer-Gene Interaction Analyses Identified the Epidermal Growth Factor Receptor as a Susceptibility Gene for Type 2 Diabetes Mellitus [PDF]
Diabetes & Metabolism Journal, 2021 Background Genetic interactions are known to play an important role in the missing heritability problem for type 2 diabetes mellitus (T2DM). Interactions between enhancers and their target genes play important roles in gene regulation and disease ...
Yang Yang +4 more
doaj +1 more source