Results 31 to 40 of about 50,815 (199)

Statistical Modeling of Epistasis and Linkage Decay using Logic Regression [PDF]

open access: yes, 2008
Logic regression has been recognized as a tool that can identify and model non-additive genetic interactions using Boolean logic groups. Logic regression, TASSEL-GLM and SAS-GLM were compared for analytical precision using a previously characterized ...
Jean-Luc Jannink   +4 more
core   +2 more sources

Influence of epistasis on response to genomic selection using complete sequence data

open access: yesGenetics Selection Evolution, 2017
Background The effect of epistasis on response to selection is a highly debated topic. Here, we investigated the impact of epistasis on response to sequence-based selection via genomic best linear prediction (GBLUP) in a regime of strong non-symmetrical ...
Natalia S. Forneris   +3 more
doaj   +1 more source

Dominance, Epistasis and the Genetics of Postzygotic Isolation [PDF]

open access: yesGenetics, 2000
AbstractThe sterility and inviability of species hybrids can be explained by between-locus “Dobzhansky-Muller” incompatibilities: alleles that are fit on their “normal” genetic backgrounds sometimes lower fitness when brought together in hybrids.
M, Turelli, H A, Orr
openaire   +2 more sources

Functional Regression Models for Epistasis Analysis of Multiple Quantitative Traits.

open access: yesPLoS Genetics, 2016
To date, most genetic analyses of phenotypes have focused on analyzing single traits or analyzing each phenotype independently. However, joint epistasis analysis of multiple complementary traits will increase statistical power and improve our ...
Futao Zhang   +4 more
doaj   +1 more source

Estimation of epistasis and genetic components of variance for different traits in cucumber (Cucumis sativus)

open access: yesThe Indian Journal of Agricultural Sciences, 2021
To estimate epistasis and components of genetic variance a study was carried out during 2016 and 2017 at Experimental Research Farm of Department of Vegetable Science, Dr YSP UH & F Nauni, Solan, (HP) and data were recorded for different qualitative and
REENA KUMARI, RAMESH KUMAR, MEENU GUPTA
doaj   +1 more source

Learning genetic epistasis using Bayesian network scoring criteria [PDF]

open access: yesBMC Bioinformatics, 2011
Gene-gene epistatic interactions likely play an important role in the genetic basis of many common diseases. Recently, machine-learning and data mining methods have been developed for learning epistatic relationships from data. A well-known combinatorial method that has been successfully applied for detecting epistasis is Multifactor Dimensionality ...
Jiang, X   +3 more
openaire   +3 more sources

Significance of linkage disequilibrium and epistasis on genetic variances in noninbred and inbred populations

open access: yesBMC Genomics, 2022
Background The influence of linkage disequilibrium (LD), epistasis, and inbreeding on genotypic variance continues to be an important area of investigation in genetics and evolution.
José Marcelo Soriano Viana   +1 more
doaj   +1 more source

On the relationship between epistasis and genetic variance heterogeneity [PDF]

open access: yesJournal of Experimental Botany, 2017
AbstractEpistasis and genetic variance heterogeneity are two non-additive genetic inheritance patterns that are often, but not always, related. Here we use theoretical examples and empirical results from analyses of experimental data to illustrate the connection between the two.
Forsberg, Simon, Carlborg, Örjan
openaire   +2 more sources

A strategy to apply quantitative epistasis analysis on developmental traits

open access: yesBMC Genetics, 2017
Background Genetic interactions are keys to understand complex traits and evolution. Epistasis analysis is an effective method to map genetic interactions. Large-scale quantitative epistasis analysis has been well established for single cells.
Marta K. Labocha   +3 more
doaj   +1 more source

Evolutionary footprint of epistasis. [PDF]

open access: yesPLoS Computational Biology, 2018
Variation of an inherited trait across a population cannot be explained by additive contributions of relevant genes, due to epigenetic effects and biochemical interactions (epistasis).
Gabriele Pedruzzi   +2 more
doaj   +1 more source

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