Results 81 to 90 of about 2,663,291 (229)
Epistasis and immunity: the role of genetic interactions in autoimmune diseases
Immunology, 2012 SummaryAutoimmune disorders are a complex and varied group of diseases that are caused by breakdown of self‐tolerance. The aetiology of autoimmunity is multi‐factorial, with both environmental triggers and genetically determined risk factors. In recent years, it has been increasingly recognized that genetic risk factors do not act in isolation, but ...
A. M. Rose, L. C. Bell
semanticscholar +5 more sources
Information content of colored motifs in complex networks [PDF]
, 2011 We study complex networks in which the nodes of the network are tagged with different colors depending on the functionality of the nodes (colored graphs), using information theory applied to the distribution of motifs in such networks.
Arend Hintze +4 more
core +1 more source
Genetic mapping of sterile genes with epistasis in backcross designs [PDF]
Heredity, 2013 The mapping of sterile genes is an essential issue, which should be solved for the investigation of sterility mechanism in wide hybridization of plants. However, the methods formerly developed cannot address the problem of mapping sterile loci with epistasis.
Shang-Qian Xie, Bruce Walsh, J Chen
openaire +3 more sources
Revista Facultad Nacional de Agronomía Medellín, 2019 Genetic parameters such as leaf relative water content, leaf chlorophyll content, plant height, above-ground biomass, harvest index, grain yield, and grain yield components of Bousselam/Mrb5 durum wheat (Triticum durum Desf.) cross were estimated based ...
Manel Salmi +6 more
doaj +1 more source
Rheumatoid arthritis identification using epistasis analysis through computational models
Biomedical and Biotechnology Research Journal, 2020 Rheumatoid arthritis (RA) is an autoimmune disorder that damages joints irreversibly. Many RA illnesses were also related to complex genetic characteristics and genetic interactions as well.
R Manavalan, S Priya
doaj +1 more source
Association mapping for epistasis and environmental interaction of yield traits in 323 cotton cultivars under 9 different environments. [PDF]
PLoS ONE, 2014 Improving yield is a major objective for cotton breeding schemes, and lint yield and its three component traits (boll number, boll weight and lint percentage) are complex traits controlled by multiple genes and various environments.
Yinhua Jia +14 more
doaj +1 more source
Advanced Science, EarlyView.The GeneHunter‐Gene‐Level Association (GH‐GLA) pipeline enables high‐throughput gene identification in an indexed EMS population of wheat cultivar KN9204. It identifies 5905 trait‐associated wheat genes and validates key regulators of kernel weight and spikelet architecture via gene editing and haplotype analysis.
Haojie Wang +16 more
wiley +1 more source
Epistasis Is a Major Determinant of the Additive Genetic Variance in Mimulus guttatus
PLoS Genetics, 2015 The influence of genetic interactions (epistasis) on the genetic variance of quantitative traits is a major unresolved problem relevant to medical, agricultural, and evolutionary genetics.
P. Monnahan, J. Kelly
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance The same mutation can have different effects among individuals, and one reason for this is the presence of additional mutations, a relationship known as epistasis. Epistatic effects are difficult to predict.
Robert Rauscher +11 more
semanticscholar +1 more source
Detecting epistasis via Markov bases [PDF]
, 2010 Rapid research progress in genotyping techniques have allowed large genome-wide association studies. Existing methods often focus on determining associations between single loci and a specific phenotype.
Malaspinas, Anna-Sapfo, Uhler, Caroline
core +1 more source