Results 81 to 90 of about 50,815 (199)
Complexity of evolutionary equilibria in static fitness landscapes [PDF]
, 2013 A fitness landscape is a genetic space -- with two genotypes adjacent if they differ in a single locus -- and a fitness function. Evolutionary dynamics produce a flow on this landscape from lower fitness to higher; reaching equilibrium only if a local ...
Kaznatcheev, Artem
core
New Phytologist, EarlyView.Summary Hybridization and polyploidy are major drivers of plant diversification, often accompanied by shifts in gene expression and genome composition. Small RNAs (smRNAs) are thought to influence such genomic changes, particularly through their interactions with transposable elements (TEs).
Mimmi C. Eriksson +6 more
wiley +1 more source
Frontiers in Plant Science, 2018 An “immortalized F2” (IF2) population and two reciprocal backcross (HSBCF1 and MARBCF1) populations were constructed to investigate the genetic bases of fiber quality traits in upland cotton across four different environments.
Cong Li +12 more
doaj +1 more source
Genetic and Molecular Determinants of Familial Transmission of Skeletal Malocclusions
Orthodontics &Craniofacial Research, EarlyView.ABSTRACT Families studies conducted in different ethnic populations worldwide have helped elucidate the molecular and genetic factors involved in the development of skeletal class III malocclusion. Therefore, the aim of this study is to provide an updated summary.
Alexandra Dehesa‐Santos +3 more
wiley +1 more source
wtest: an integrated R package for genetic epistasis testing [PDF]
BMC Medical Genomics, 2019 AbstractBackgroundWith the increasing amount of high-throughput genomic sequencing data, there is a growing demand for a robust and flexible tool to perform interaction analysis. The identification of SNP-SNP, SNP-CpG, and higher order interactions helps explain the genetic etiology of human diseases, yet genome-wide analysis for interactions has been ...
Rui Sun +5 more
openaire +3 more sources
Structural Variations Contribute to Subspeciation and Yield Heterosis in Rice
Plant Biotechnology Journal, EarlyView.ABSTRACT Yield heterosis has been extensively exploited in hybrid breeding, with intersubspecific hybrids often exhibiting the most pronounced effects. However, developing elite hybrids remains a laborious and time‐consuming process. The genetic basis of heterosis has been debated for over a century, hindered largely by the lack of high‐quality genomes.
Zhiwu Dan, Yunping Chen, Wenchao Huang
wiley +1 more source
Epistasis and its contribution to genetic variance components. [PDF]
Genetics, 1995 Abstract We present a new parameterization of physiological epistasis that allows the measurement of epistasis separate from its effects on the interaction (epistatic) genetic variance component. Epistasis is the deviation of two-locus genotypic values from the sum of the contributing single-locus genotypic values.
J M, Cheverud, E J, Routman
openaire +2 more sources
Epistasis in a model of molecular signal transduction. [PDF]
PLoS Computational Biology, 2011 Biological functions typically involve complex interacting molecular networks, with numerous feedback and regulation loops. How the properties of the system are affected when one, or several of its parts are modified is a question of fundamental interest,
Alain Pumir, Boris Shraiman
doaj +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Low temperature is a critical abiotic stress that imposes major constraints on the sustainable development of the fruit tree industry. Although exogenous dopamine has been shown to enhance cold tolerance in plants, its molecular mechanisms in apple (Malus domestica) remain poorly understood.
Kexin Tan +9 more
wiley +1 more source
Clinical Implications of Digenic Inheritance and Epistasis in Primary Immunodeficiency Disorders
Frontiers in Immunology, 2018 The existence of epistasis in humans was first predicted by Bateson in 1909. Epistasis describes the non-linear, synergistic interaction of two or more genetic loci, which can substantially modify disease severity or result in entirely new phenotypes ...
Rohan Ameratunga +9 more
doaj +1 more source