Results 51 to 60 of about 60,491 (200)

Generation mean analysis of the key earliness related traits in cowpea (Vigna unguiculata (L.) Walp)

Scientific African, 2022
The nature of gene action controlling agronomic traits enables plant breeders to execute a successful crop improvement programme. To elucidate the type of gene action governing the key earliness related traits in cowpea, seven populations of the six ...
Emmanuel Yaw Owusu, Francis Kusi, Alexander Wireko Kena, Richard Akromah, Frederick Justice Awuku, Patrick Attamah, Gloria Mensah   +6 more
doaj   +1 more source

Quantitative analyses of empirical fitness landscapes

, 2012
The concept of a fitness landscape is a powerful metaphor that offers insight into various aspects of evolutionary processes and guidance for the study of evolution.
de Visser, J. Arjan G. M., Franke, Jasper, Krug, Joachim, Schenk, Martijn F., Szendro, Ivan G.   +4 more
core   +2 more sources

The nk model and population genetics [PDF]

, 2005
The nk model of fitness interactions is examined. This model has been used by previous authors to investigate the effects of fitness epistasis on substitution dynamics in molecular evolution, and to make broader claims about the importance of epistasis ...
Barton, Barton, Bergman, Burch, Coyne, Edmands, Elena, Elena, Felsenstein, Fisher, Fitch, Fontana, Fraser, Gavrilets, Gillespie, Gillespie, Gillespie, Gillespie, Gumbel, Hansen, Hartl, Jeong, Kauffman, Kauffman, Kauffman, Kichler Holder, Kimura, Kimura, Kondrashov, Korona, Lenski, Macken, Mani, Maynard Smith, Moore, Ohta, Ohta, Ohta, Ohta, Orr, Orr, Orr, Peck, Perelson, Phillips, Provine, Schrag, Solow, Stephan, Tachida, Tachida, Weinberger, Welch, Whitlock, Zeng   +54 more
core   +2 more sources

Multi-Objective Artificial Bee Colony Algorithm Based on Scale-Free Network for Epistasis Detection [PDF]

, 2022
Yijun Gu, Yan Sun, Junliang Shang, Feng Li, Boxin Guan, Jin‐Xing Liu   +5 more
openalex   +1 more source

Early life exploration behaviour and life‐history loci are colocalized in an adaptive genomic hotspot in Atlantic salmon

Journal of Animal Ecology, EarlyView.
The genetic architecture of phenotypic correlations offers insights into how natural selection operates in the wild. Two functional phenotypes in Atlantic salmon, early life exploration and age‐at‐maturity, are correlated at an adaptive genomic hotspot, but through distinct genetic markers (SNPs), ruling out causality.
Tutku Aykanat, Jaakko Erkinaro
wiley   +1 more source

Epistasis detectably alters correlations between genomic sites in a narrow parameter window.

PLoS ONE, 2019
Different genomic sites evolve inter-dependently due to the combined action of epistasis, defined as a non-multiplicative contribution of alleles at different loci to genome fitness, and the physical linkage of different loci in genome.
Gabriele Pedruzzi, Igor M Rouzine
doaj   +1 more source

Effects of Epistasis and Pleiotropy on Fitness Landscapes

, 2013
The factors that influence genetic architecture shape the structure of the fitness landscape, and therefore play a large role in the evolutionary dynamics. Here the NK model is used to investigate how epistasis and pleiotropy -- key components of genetic
A Dawid, AI Khan, B Østman, DJ Kvitek, FJ Poelwijk, H Chou, HA Orr, MC Whitlock, MC Whitlock, MM Desai, RL Unckless, S Gavrilets, S Gavrilets, S Kauffman, S Kauffman, V Mustonen   +15 more
core   +1 more source

Accounting for genetic interactions improves modeling of individual quantitative trait phenotypes in yeast. [PDF]

, 2016
Experiments in model organisms report abundant genetic interactions underlying biologically important traits, whereas quantitative genetics theory predicts, and data support, the notion that most genetic variance in populations is additive.
Bloom, Joshua S, Carlborg, Örjan, Forsberg, Simon KG, Kruglyak, Leonid, Sadhu, Meru J   +4 more
core   +3 more sources

A century of theories of balancing selection

Biological Reviews, EarlyView.
ABSTRACT Traits that affect organismal fitness are often highly genetically variable. This genetic variation is vital for populations to adapt to their environments, but it is also surprising given that nature – after all – ‘selects’ the best genotypes at the expense of those that fall short.
Filip Ruzicka, Martyna K. Zwoinska, Debora Goedert, Hanna Kokko, Xiang‐Yi Li Richter, Iain R. Moodie, Sofie Nilén, Colin Olito, Erik I. Svensson, Peter Czuppon, Tim Connallon   +10 more
wiley   +1 more source

Long-Range Epistasis Mediated by Structural Change in a Model of Ligand Binding Proteins. [PDF]

PLoS ONE, 2016
Recent analyses of amino acid mutations in proteins reveal that mutations at many pairs of sites are epistatic-i.e., their effects on fitness are non-additive-the combined effect of two mutations being significantly larger or smaller than the sum of ...
Erik D Nelson, Nick V Grishin
doaj   +1 more source