Results 71 to 80 of about 59,992 (241)
Information content of colored motifs in complex networks [PDF]
, 2011 We study complex networks in which the nodes of the network are tagged with different colors depending on the functionality of the nodes (colored graphs), using information theory applied to the distribution of motifs in such networks.
Arend Hintze +4 more
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Epistasis in protein evolution [PDF]
Protein Science, 2016 AbstractThe structure, function, and evolution of proteins depend on physical and genetic interactions among amino acids. Recent studies have used new strategies to explore the prevalence, biochemical mechanisms, and evolutionary implications of these interactions—called epistasis—within proteins.
Tyler N. Starr, Joseph W. Thornton
openaire +3 more sources
Journal of Integrative Plant Biology, EarlyView.During postharvest cold storage of apples, the NAC transcription factor MdNAC83 binds to the promoters and activates the expression of downstream genes and is regulated by E3 ligases, which promote its ubiquitination and degradation. Genetic variants in MdNAC83 and its downstream genes form a network to regulate apple fruit storability.
Bei Wu +7 more
wiley +1 more source
Epistasis detectably alters correlations between genomic sites in a narrow parameter window.
PLoS ONE, 2019 Different genomic sites evolve inter-dependently due to the combined action of epistasis, defined as a non-multiplicative contribution of alleles at different loci to genome fitness, and the physical linkage of different loci in genome.
Gabriele Pedruzzi, Igor M Rouzine
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Long-Range Epistasis Mediated by Structural Change in a Model of Ligand Binding Proteins. [PDF]
PLoS ONE, 2016 Recent analyses of amino acid mutations in proteins reveal that mutations at many pairs of sites are epistatic-i.e., their effects on fitness are non-additive-the combined effect of two mutations being significantly larger or smaller than the sum of ...
Erik D Nelson, Nick V Grishin
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Documenting homoploid hybrid speciation
Molecular Ecology, EarlyView.Abstract Homoploid hybrid speciation is challenging to document because hybridization can lead to outcomes other than speciation. Thus, some authors have argued that establishment of homoploid hybrid speciation should include evidence that reproductive barriers isolating the hybrid neo‐species from its parental species were derived from hybridization ...
Zhiqin Long, Loren H. Rieseberg
wiley +1 more source
Nonparametric method for genomics-based prediction of performance of quantitative traits involving epistasis in plant breeding. [PDF]
PLoS ONE, 2012 Genomic selection (GS) procedures have proven useful in estimating breeding value and predicting phenotype with genome-wide molecular marker information.
Xiaochun Sun, Ping Ma, Rita H Mumm
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Generalized Walsh Transforms and Epistasis [PDF]
Bulletin of the Belgian Mathematical Society - Simon Stevin, 2006 In this note, we introduce and briefly study a non-binary analogue of the “classical” Walsh transform. It is shown that this transform allows to rewrite the definition of normalized epistasis in terms of generalized Walsh coecients, in a way which is both practical and elegant.
Iglesias, M. T. +2 more
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Mixed Outcomes in Recombination Rates After Domestication: Revisiting Theory and Data
Molecular Ecology, EarlyView.ABSTRACT The process of domestication has altered many phenotypes. Selection on these phenotypes has long been hypothesised to indirectly select for increases in the genome‐wide recombination rate. This hypothesis is potentially consistent with theory on the evolution of the recombination rate, but empirical support has been unclear. We review relevant
Madeline Bursell +6 more
wiley +1 more source
Complexity of evolutionary equilibria in static fitness landscapes [PDF]
, 2013 A fitness landscape is a genetic space -- with two genotypes adjacent if they differ in a single locus -- and a fitness function. Evolutionary dynamics produce a flow on this landscape from lower fitness to higher; reaching equilibrium only if a local ...
Kaznatcheev, Artem
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