Results 81 to 90 of about 55,446 (204)
Nonparametric method for genomics-based prediction of performance of quantitative traits involving epistasis in plant breeding. [PDF]
PLoS ONE, 2012 Genomic selection (GS) procedures have proven useful in estimating breeding value and predicting phenotype with genome-wide molecular marker information.
Xiaochun Sun, Ping Ma, Rita H Mumm
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Agrosystems, Geosciences &Environment, Volume 8, Issue 2, June 2025.Abstract Despite the enormous achievements recorded in tomato (Solanum lycopersicum L.) breeding using traditional and molecular approaches, most cultivars find humid environments highly unfavorable. As a result, fruit production cannot meet the rapidly increasing global demand.
Chikezie Onuora Ene +6 more
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Epistasis correlates to genomic complexity [PDF]
Proceedings of the National Academy of Sciences, 2006 Whether systematic genetic interactions (epistasis) occur at the genomic scale remains a challenging topic in evolutionary biology. Epistasis should make a significant contribution to variation in complex traits and influence the evolution of genetic systems as sex, diploidy, dominance, or the contamination of genomes with deleterious mutations.
Sanjuán, Rafael, Elena, Santiago F.
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Protein Science, Volume 34, Issue 6, June 2025.Abstract The complex genotype‐to‐phenotype relationships in Mendelian diseases can be elucidated by mutation‐induced disturbances to the networks of molecular interactions (interactomes) in human cells. Missense and nonsense mutations cause distinct perturbations within the human protein interactome, leading to functional and phenotypic effects with ...
Ting‐Yi Su, Yu Xia
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PLoS Computational BiologyEpistasis among driver mutations is pervasive and explains relevant features of cancer, such as differential therapy response and convergence towards well-characterized molecular subtypes.
Carla Alejandre +2 more
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The Plant Genome, Volume 18, Issue 2, June 2025.Abstract Cannabis (Cannabis sativa L.), once sidelined by decades of prohibition, has now gained recognition as a multifaceted and promising plant in both medical research and commercial applications following its recent legalization. This study leverages a genome‐wide association study (GWAS) on 174 drug‐type Cannabis accessions from the legal ...
Maxime de Ronne, Davoud Torkamaneh
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COMPUTING AND INFORMATICS, 1995 In this note, we compare two previously introduced notions of epistasis and prove that they are essentially equivalent.
van Hove, H., Verschoren, Alain
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Evaluating Methods for Modeling Epistasis Networks with Application to Head and Neck Cancer
Cancer Informatics, 2015 Epistasis helps to explain how multiple single-nucleotide polymorphisms (SNPs) interact to cause disease. A variety of tools have been developed to detect epistasis.
Rajesh Talluri, Sanjay Shete
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Privacy-preserving decision tree for epistasis detection
Cybersecurity, 2019 The interaction between gene loci, namely epistasis, is a widespread biological genetic phenomenon. In genome-wide association studies(GWAS), epistasis detection of complex diseases is a major challenge. Although many approaches using statistics, machine
Qingfeng Chen, Xu Zhang, Ruchang Zhang
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Effects of Epistasis and Pleiotropy on Fitness Landscapes
, 2013 The factors that influence genetic architecture shape the structure of the fitness landscape, and therefore play a large role in the evolutionary dynamics. Here the NK model is used to investigate how epistasis and pleiotropy -- key components of genetic
A Dawid +15 more
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