Results 81 to 90 of about 38,666 (258)
mBio, 2018 Mosaic interspecifically acquired alleles of the multiple transferable resistance (mtr) efflux pump operon correlate with increased resistance to azithromycin in Neisseria gonorrhoeae in epidemiological studies.
Crista B. Wadsworth +3 more
semanticscholar +1 more source
Journal of Animal Breeding and Genetics, EarlyView.ABSTRACT Fitness traits described as a ratio often display non‐normal distributions; consequently, transformations are frequently applied to improve normality prior to the estimation of genetic parameters. However, the impact of different transformations on genetic parameter estimates depends on the dataset at hand.
Evan Hartono +5 more
wiley +1 more source
G3: Genes, Genomes, Genetics, 2019 Epistasis is an important contributor to genetic variance. In inbred populations, pairwise epistasis is present as additive by additive interactions.
Nicholas Santantonio +2 more
doaj +1 more source
Nonparametric method for genomics-based prediction of performance of quantitative traits involving epistasis in plant breeding. [PDF]
PLoS ONE, 2012 Genomic selection (GS) procedures have proven useful in estimating breeding value and predicting phenotype with genome-wide molecular marker information.
Xiaochun Sun, Ping Ma, Rita H Mumm
doaj +1 more source
Generalized Walsh Transforms and Epistasis [PDF]
Bulletin of the Belgian Mathematical Society - Simon Stevin, 2006 In this note, we introduce and briefly study a non-binary analogue of the “classical” Walsh transform. It is shown that this transform allows to rewrite the definition of normalized epistasis in terms of generalized Walsh coecients, in a way which is both practical and elegant.
Iglesias, M. T. +2 more
openaire +3 more sources
Journal of Animal Breeding and Genetics, EarlyView.ABSTRACT Genetic progress of breeding programs is highly dependent on the size of reference populations and the relatedness between reference populations and selection candidates. Many reasons can lead a population to split into several subpopulations (sanitary, physiological, political reasons, etc.).
M. Wicki, A. Legarra, J. Raoul
wiley +1 more source
Fitness ranking of individual mutants drives patterns of epistatic interactions in HIV-1. [PDF]
PLoS ONE, 2011 Fitness interactions between mutations, referred to as epistasis, can strongly impact evolution. For RNA viruses and retroviruses with their high mutation rates, epistasis may be particularly important to overcome fitness losses due to the accumulation ...
Javier P Martínez +6 more
doaj +1 more source
Documenting homoploid hybrid speciation
Molecular Ecology, EarlyView.Abstract Homoploid hybrid speciation is challenging to document because hybridization can lead to outcomes other than speciation. Thus, some authors have argued that establishment of homoploid hybrid speciation should include evidence that reproductive barriers isolating the hybrid neo‐species from its parental species were derived from hybridization ...
Zhiqin Long, Loren H. Rieseberg
wiley +1 more source
PLoS Computational BiologyEpistasis among driver mutations is pervasive and explains relevant features of cancer, such as differential therapy response and convergence towards well-characterized molecular subtypes.
Carla Alejandre +2 more
doaj +1 more source
Epistasis correlates to genomic complexity [PDF]
Proceedings of the National Academy of Sciences, 2006 Whether systematic genetic interactions (epistasis) occur at the genomic scale remains a challenging topic in evolutionary biology. Epistasis should make a significant contribution to variation in complex traits and influence the evolution of genetic systems as sex, diploidy, dominance, or the contamination of genomes with deleterious mutations.
Sanjuán, Rafael, Elena, Santiago F.
openaire +4 more sources