Generation of corneal epithelial cells from induced pluripotent stem cells derived from human dermal fibroblast and corneal limbal epithelium. [PDF]
PLoS ONE, 2012 Induced pluripotent stem (iPS) cells can be established from somatic cells. However, there is currently no established strategy to generate corneal epithelial cells from iPS cells.
Ryuhei Hayashi +10 more
doaj +1 more source
Growth regulation in Hydra. Relationship between epithelial cell cycle length and growth rate [PDF]
, 1984 The relationship between epithelial cell production and growth rate was investigated in Hydra attenuata under different feeding regimes. The increase of epithelial cell number was compared to the duration of the epithelial cell cycle using standard ...
Bosch, Thomas C. G., David, Charles N.
core +1 more source
Gonococcal invasion into epithelial cells depends on both cell polarity and ezrin.
PLoS Pathogens, 2021 Neisseria gonorrhoeae (GC) establishes infection in women from the cervix, lined with heterogeneous epithelial cells from non-polarized stratified at the ectocervix to polarized columnar at the endocervix.
Qian Yu +4 more
doaj +1 more source
Poly-l/dl-lactic acid films functionalized with collagen IV as carrier substrata for corneal epithelial stem cells [PDF]
, 2019 Limbal epithelial stem cells (LESCs) are responsible for the renewal of corneal epithelium. Cultivated limbal epithelial transplantation is the current treatment of choice for restoring the loss or dysfunction of LESCs.
Calonge Cano, Margarita +7 more
core +3 more sources
Stem Cell Reports, 2014 B-lymphocyte-induced nuclear maturation protein 1 (BLIMP1) was previously reported to define a sebaceous gland (SG) progenitor population in the epidermis.
Kai Kretzschmar +8 more
doaj +1 more source
A symmetry breaking mechanism for epithelial cell polarization [PDF]
Physical Review E 80 (3), 031919 (2009), 2010 In multicellular organisms, epithelial cells form layers separating compartments responsible for different physiological functions. At the early stage of epithelial layer formation, each cell of an aggregate defines an inner and an outer side by breaking the symmetry of its initial state, in a process known as epithelial polarization.
arxiv +1 more source
3D shape of epithelial cells on curved substrates [PDF]
Phys. Rev. X 11, 031028 (2021), 2020 It is widely recognized that the shape of epithelial cells is determined by the tension generated by the actomyosin cortex and the adhesion of cells to the substrate and to each other. To account for these biological and structural contributions to cell shape, different physical models have been proposed.
arxiv +1 more source
STAR Protocols, 2023 Summary: Primary human mammary epithelial cells (pHMECs) are known to be remarkably difficult to engineer genetically. Here, we present a protocol for efficient transduction of pHMECs using a baboon retroviral envelope glycoprotein for pseudotyping of ...
Sonia Pastor +5 more
doaj
Function and mechanisms of T cells in the damage and repair of lung epithelial cells
生物医学转化, 2023 Lung epithelial cells play a protective role in the respiratory system. However, various pathological factors such as infection, trauma, and inflammation can lead to damage to lung epithelial cells, causing lung diseases.
Liu Enzhuo, Liu Zhichun, Wen Zhenke
doaj +1 more source
Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition. [PDF]
, 2016 The epithelial-mesenchymal transition (EMT) endows carcinoma cells with phenotypic plasticity that can facilitate the formation of cancer stem cells (CSCs) and contribute to the metastatic cascade.
Banno, Asoka +15 more
core +2 more sources