Contact inhibition of locomotion and junctional mechanics guide collective cell behavior in epithelial wound repair [PDF]
arXiv, 2017 Epithelial tissues form physically integrated barriers against the external environment protecting organs from infection and invasion. Within each tissue, epithelial cells respond to different challenges that can potentially compromise tissue integrity.
arxiv
A Mechanical Instability in Planar Epithelial Monolayers Leads to Cell Extrusion [PDF]
, 2018 In cell extrusion, a cell embedded in an epithelial monolayer loses its apical or basal surface and is subsequently squeezed out of the monolayer by neighboring cells. Cell extrusions occur during apoptosis, epithelial-mesenchymal transition, or pre-cancerous cell invasion.
arxiv +1 more source
Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells. [PDF]
, 2007 Candida albicans is the most common cause of hematogenously disseminated and oropharyngeal candidiasis. Both of these diseases are characterized by fungal invasion of host cells. Previously, we have found that C.
Edwards, John E +8 more
core +3 more sources
Anomalous diffusion on dynamical networks: A model for interacting epithelial cell migration [PDF]
, 2002 We propose a model for cell migration where epithelial cells are able to detect trajectories of other cells and try to follow them. As cells move along in 2D cell culture, they mark their paths by loosing tiny parts of cytoplasm. Any cell moving on a surface where other cells have moved before faces a network of cell trajectories, which it tries to ...
arxiv +1 more source
Collective epithelial migration mediated by the unbinding of hexatic defects [PDF]
arXiv, 2023 Collective cell migration in epithelia relies on cell intercalation: a local remodelling of the cellular network that allows neighbouring cells to swap their positions. Unlike foams and passive cellular fluid, in epithelial intercalation these rearrangements crucially depend on activity. During these processes, the local geometry of the network and the
arxiv
The Induction of EMT and Activation of Adipose Stem Cells in Correlation with the Secretion of LTBP-1 in Mammary Cells [PDF]
, 2015 This work is part of an ongoing study that investigates the upregulation of LTBP-1 in mammary epithelial cells as well as the differentiation of breast adipose stem cells (BASCs) in the presence of TGF-β1.
Griggs, Lauren +2 more
core +1 more source
Peribiliary glands are key in regeneration of the human biliary epithelium after severe bile duct injury [PDF]
, 2019 Peribiliary glands (PBG) are a source of stem/progenitor cells organized in a cellular network encircling large bile ducts. Severe cholangiopathy with loss of luminal biliary epithelium has been proposed to activate PBG, resulting in cell proliferation ...
Carpino, Guido +15 more
core +3 more sources
iScience, 2022 Summary: The Mammary gland undergoes complicated epithelial remodeling to form lobuloalveoli during pregnancy, in which basal epithelial cells remarkably increase to form a basket-like architecture. However, it remains largely unknown how dormant mammary
Ruiqi Liu +11 more
doaj
Dbl oncogene expression in MCF-10 A epithelial cells disrupts mammary acinar architecture, induces EMT and angiogenic factor secretion. [PDF]
, 2015 The proteins of the Dbl family are guanine nucleotide exchange factors (GEFs) of Rho GTPases and are known to be involved in cell growth regulation. Alterations of the normal function of these proteins lead to pathological processes such as developmental
Bosco MC +10 more
core +1 more source
Ks1, an epithelial cell-specific gene, responds to early signals of head formation in Hydra [PDF]
, 1994 As a molecular marker for head specification in Hydra, we have cloned an epithelial cell-specific gene which responds to early signals of head formation.
Bosch, Thomas C. G. +3 more
core