Results 61 to 70 of about 5,847,660 (310)

EGF-induced bronchial epithelial cells drive neutrophil chemotactic and anti-apoptotic activity in asthma [PDF]

, 2013
Chronic damage and repair of the bronchial epithelium are features of asthma. We have previously reported that ex vivo stimulation of normal bronchial epithelial cells with epidermal growth factor (EGF), a key factor of epithelial repair, enhances the ...
Donna E Davies, Cornelius Victoria, Grégory Seumois, Lau, LC, Karl J Staples, Cornelius, Victoria, Dorinsky, P, Victoria Cornelius, Davies Donna E., Dinesh Bagmane (457229), Staples, Karl J., Uddin, Mohib, Ratko Djukanović, Pandurangan Vijayanand, Victoria Cornelius (457230), Lau, Laurie C., Mohib Uddin (457226), Karl J. Staples (457228), Bagmane, Dinesh, Ratko Djukanović (457232), Paul Dorinsky, Pandurangan Vijayanand (277869), Djukanović Ratko, Lau, Laurie C, Grégory Seumois (5656213), Lau Laurie C., Staples, KJ, Vijayanand, P, Vijayanand, Pandurangan, Laurie C. Lau (457227), Seumois, G, Uddin, M, Staples, Karl J, Davies, Donna E, Staples Karl J., Davies, DE, Donna E. Davies (137702), Seumois Grégory, Djukanović, R, Dinesh Bagmane, Djukanović, Ratko, Cornelius, V, Davies, Donna E., Laurie C Lau, Dorinsky Paul, Paul Dorinsky (457231), Dorinsky, Paul, Seumois, Grégory, Bagmane Dinesh, Uddin Mohib, Bagmane, D, Mohib Uddin, Vijayanand Pandurangan   +52 more
core   +2 more sources

In vivo organoid growth monitoring by stimulated Raman histology

npj Imaging
Patient-derived tumor organoids have emerged as a crucial tool for assessing the efficacy of chemotherapy and conducting preclinical drug screenings.
Barbara Sarri, Véronique Chevrier, Flora Poizat, Sandro Heuke, Florence Franchi, Louis De Franqueville, Eddy Traversari, Jean-Philippe Ratone, Fabrice Caillol, Yanis Dahel, Solène Hoibian, Marc Giovannini, Cécile de Chaisemartin, Romain Appay, Géraldine Guasch, Hervé Rigneault   +15 more
doaj   +1 more source

The role of epithelial cells in fibrosis: Mechanisms and treatment

Pharmacological Research
Fibrosis is a pathological process that affects multiple organs and is considered one of the major causes of morbidity and mortality in multiple diseases, resulting in an enormous disease burden.
Liuyi Luo, Wei Zhang, Siyao You, Xinyan Cui, Hua Tu, Qiao Yi, Jianjun Wu, Ousheng Liu   +7 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

The transcriptome of wild-type and immortalized corneal epithelial cells [PDF]

, 2021
Cellular immortalization enables indefinite expansion of cultured cells. However, the process of cell immortalization sometimes changes the original nature of primary cells.
SUGANO, Eriko, TAKAI, Yoshihiro, FUKUDA, Tomokazu, WU, Tao, ORIMOTO, Ai, FURUYA, Kai, KIYONO, Tohru, KUROSE, Takahiro, TOMITA, Hiroshi   +8 more
core  

Genetic barcoding uncovers the clonal makeup of solid and liquid biopsies and their ability to capture intra-tumoral heterogeneity

Molecular Systems Biology
Intratumoral heterogeneity (ITH) is fueling tumor progression in breast cancer, as specific clones present within a tumor may have a selective advantage to colonize distant organs and escape therapy.
Antonin Serrano, Tom S Weber, Jean Berthelet, Sarah Ftouni, Farrah El-Saafin, Samuel Lee, Elgene Lim, Emmanuelle Charafe-Jauffret, Christophe Ginestier, David Williams, Frédéric Hollande, Belinda Yeo, Sarah-Jane Dawson, Shalin H Naik, Delphine Merino   +14 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Investigating the properties of cancer stem cells and epithelial to mesenchymal transition in human prostate cancer [PDF]

, 2012
In recent years, the cancer stem cell hypothesis has emerged as a compelling but controversial model of cancer progression. Contrary to the clonal evolution model, the cancer stem cell hypothesis postulates that, akin to normal tissues, tumours are ...
Dunning-Foreman, NL
core  

Human Cancer Cells Express Slug-based Epithelial-Mesenchymal Transition Gene Signature Obtained in Vivo [PDF]

, 2011
The biological mechanisms underlying cancer cell motility and invasiveness remain unclear, although it has been hypothesized that they involve some type of epithelial-mesenchymal transition (EMT).
Rumjantseva Viktoria, Cheng Weiyi, Viktoria Rumjantseva, Kandel Jessica J, Jessica J Kandel, Yamashiro, Darrell, Jianzhong Huang, Peter D. Canoll, Huang, Jianzhong, Dimitris Anastassiou, Anastassiou Dimitris, Darrell J Yamashiro, Yamashiro Darrell J, Canoll Peter D, Canoll, Peter D., Kandel, Jessica J., Wei-yi Cheng, Rumjantseva, Viktoria, Huang Jianzhong, Jessica J. Kandel, Cheng, Weiyi, Darrell J. Yamashiro, Weiyi Cheng, Anastassiou, Dimitris, Peter D Canoll   +24 more
core   +2 more sources

Endometrial regeneration with endometrial epithelium: homologous orchestration with endometrial stroma as a feeder

Stem Cell Research & Therapy, 2021
Background Thin endometrium adversely affects reproductive success rates with fertility treatment. Autologous transplantation of exogenously prepared endometrium can be a promising therapeutic option for thin endometrium; however, endometrial epithelial ...
Ryo Yokomizo, Yukiko Fujiki, Harue Kishigami, Hiroshi Kishi, Tohru Kiyono, Sanae Nakayama, Haruhiko Sago, Aikou Okamoto, Akihiro Umezawa   +8 more
doaj   +1 more source