Results 121 to 130 of about 212,176 (344)
Regional differences in store-operated Ca2+ entry in the epithelium of the intact human lens [PDF]
, 2009 An elevated level of Ca2+ is an important factor in cataract, yet precisely how Ca2+ enters the lens is unknown. Lens epithelial cells contain a range of G-protein–coupled receptors and receptor tyrosine kinases that induce increases in intracellular Ca2+
Duncan, George +4 more
core +1 more source
The Epithelial Sodium Channel: Recent Developments
Cellular Physiology and Biochemistry, 1993 Several types of amiloride-sensitive Na+ channels have been described in the apical membrane of tight epithelia. A highly Na+-selective, low-conductance type is found when transepithelial Na+ transport is stimulated, while different types are observed under other conditions.
Jean-Daniel Horisberger +2 more
openaire +1 more source
Advanced Functional Materials, EarlyView.MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández +7 more
wiley +1 more source
Insulin Resistance, Obesity, Hypertension, and Renal Sodium Transport
International Journal of Hypertension, 2011 Sodium transport through various nephron segments is quite important in regulating sodium reabsorption and blood pressure. Among several regulators of this process, insulin acts on almost all the nephron segments and is a strong enhancer of sodium ...
Shoko Horita +5 more
doaj +1 more source
Epithelial cell specific Raptor is required for initiation of type 2 mucosal immunity in small intestine [PDF]
, 2017 Intestinal tuft cells are one of 4 secretory cell linages in the small intestine and the source of IL-25, a critical initiator of the type 2 immune response to parasite infection. When Raptor, a critical scaffold protein for mammalian target of rapamycin
Aladegbami, Bola +6 more
core +2 more sources
Epithelial sodium channel (ENaC) and pregnancy
The FASEB Journal, 2009 A healthy pregnancy requires avid retention of sodium (Na) and plasma volume expansion (PVE) in order to provide adequate blood supply to the growing fetus. We performed in vivo and in vitro studies to
Crystal West +3 more
openaire +1 more source
Advanced Healthcare Materials, EarlyView.Patient‐specific induced pluripotent stem cells (iPSCs) can be differentiated into alveolar type II cells (iAT2s), expanded as 3D alveolospheres, and grown at physiologically relevant air–liquid interface (ALI). This study shows for the first time the infectability of iAT2s by the influenza A virus (IAV) and proves their responsiveness to the well ...
Lena Gauthier +7 more
wiley +1 more source
Indian Heart Journal, 2014 Background: The T594M variant of the β-subunit of the sodium epithelial channel (ENaC) gene may contribute to hypertension in individuals of Indo-Aryan origin.
Mohit D. Gupta +9 more
doaj +1 more source
Acetylation Stimulates the Epithelial Sodium Channel by Reducing Its Ubiquitination and Degradation*
Journal of Biological Chemistry, 2015 Background: The epithelial Na+ channel ENaC plays an important role in epithelial Na+ absorption. Results: Lysine acetylation increased ENaC abundance and current by antagonizing its ubiquitination and degradation.
P. Butler, A. Staruschenko, P. Snyder
semanticscholar +1 more source
The essential roles of metal ions in insect homeostasis and physiology [PDF]
, 2017 Metal ions play distinct roles in living organisms, including insects. Some, like sodium and potassium, are central players in osmoregulation and ‘blood and guts’ transport physiology, and have been implicated in cold adaptation.
Dow, Julian A.T.
core +1 more source