Results 111 to 120 of about 71,499 (299)
Advanced Materials Technologies, EarlyView.Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le +4 more
wiley +1 more source
Epithelial sodium channels and hypertension
The FASEB Journal, 2010 The epithelial Na channel (ENaC) mediates Na absorption in the most distal segments of the nephron, and has an important role in the regulation of extracellular fluid volume and blood pressure. Rare ENaC gain‐of‐function mutations have been described in an inherited form of hypertension, and rare loss‐of ...
openaire +1 more source
Mini-Review: Novel Therapeutic Strategies to Blunt Actions of Pneumolysin in the Lungs
Toxins, 2013 Severe pneumonia is the main single cause of death worldwide in children under five years of age. The main etiological agent of pneumonia is the G+ bacterium Streptococcus pneumoniae, which accounts for up to 45% of all cases.
Martin Leustik +15 more
doaj +1 more source
Stimulation of epithelial sodium channel activity by the sulfonylurea glibenclamide [PDF]
, 1999 The amiloride-sensitive epithelial sodium channel (ENaC) contributes to the regulation of the sodium balance and blood pressure because it mediates a rate-limiting step in sodium transport across the epithelium of the distal nephron. The activity of ENaC
Chrabi, A., Horisberger, J. D.
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Single-channel recordings from amiloride-sensitive epithelial sodium channel [PDF]
, 1985 We report here the first evidence in intact epithelial cells of unit conductance events from an amiloride-sensitive Na+ channel. The events were observed when patch-clamp recordings were made from the apical surface of cultured epithelial kidney cells ...
K. L. Hamilton, D. C. Eaton
core +1 more source
Advanced Science, EarlyView.This study explores the use of N, S co‐doped carbon quantum dots (NS‐CQDs) as carriers for riboflavin, creating NS‐CQDs‐RF composite photosensitizers. These composites improve riboflavin absorption, enhance ROS generation efficiency, and preserve corneal epithelium integrity.
Tinghong Xu +9 more
wiley +1 more source
Insulin Resistance, Obesity, Hypertension, and Renal Sodium Transport
International Journal of Hypertension, 2011 Sodium transport through various nephron segments is quite important in regulating sodium reabsorption and blood pressure. Among several regulators of this process, insulin acts on almost all the nephron segments and is a strong enhancer of sodium ...
Shoko Horita +5 more
doaj +1 more source
Nephrotic Syndrome: Oedema Formation and Its Treatment With Diuretics
Frontiers in Physiology, 2019 Oedema is a defining element of the nephrotic syndrome. Its’ management varies considerably between clinicians, with no national or international clinical guidelines, and hence variable outcomes.
Sanjana Gupta +4 more
doaj +1 more source
Advanced Science, EarlyView.Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia +17 more
wiley +1 more source
A reappraisal of aldosterone effects on the kidney: new insights provided by epithelial sodium channel cloning [PDF]
, 1997 Sodium homeostasis is crucial for the control of extra-cellular volume and blood pressure. Regulation of sodium reabsorption is mainly achieved in the distal nephron by the mineralocorticoid aldosterone, but the molecular pathway of aldosterone action ...
Rossier, B. C., Grunder, S.
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