Results 91 to 100 of about 71,499 (299)

The Regulation of Epithelial Sodium Channels in Mammalian Taste Receptor Cells [PDF]

, 2009
Nutrient recognition is one of the main physiological roles of the gustatory system. In mammals, it is well established that the taste of sodium salts is primarily mediated by sodium influx through the epithelial sodium channel.
Baquero Gonzalez, Arian F.
core   +2 more sources

Gellan Gum Fluid Gel System for Controlled‐Delivery of Cytokine‐Licensed MSC‐EVs to Enhance Corneal Repair in Limbal Stem Cell Deficiency

Advanced Healthcare Materials, EarlyView.
Gellan gum fluid gel (FG) enables controlled ocular delivery of mesenchymal stromal cell (MSC)‐derived extracellular vesicles (EV). Its shear‐thinning, solid‐liquid‐solid rheology ensures prolonged ocular retention. Sustained MSC‐EV release (∼18% in 6 hrs) supports effective EV ocular delivery.
Seyedmohammad Moosavizadeh, Ava Dashti, Thomas E. Robinson, Robyn Gaffey, Richard Moakes, Neil Lagali, Liam Grover, Thomas Ritter   +7 more
wiley   +1 more source

Regulation of the epithelial sodium channel by membrane trafficking

American Journal of Physiology-Renal Physiology, 2009
The epithelial Na+channel (ENaC) is a major regulator of salt and water reabsorption in a number of epithelial tissues. Abnormalities in ENaC function have been directly linked to several human disease states including Liddle's syndrome, psuedohypoaldosteronism, and cystic fibrosis and may be implicated in states as diverse as salt-sensitive ...
Michael B, Butterworth, Robert S, Edinger, Raymond A, Frizzell, John P, Johnson   +3 more
openaire   +3 more sources

Regulation of the epithelial sodium channel by accessory proteins [PDF]

Biochemical Journal, 2003
The epithelial sodium channel (ENaC) is of fundamental importance in the control of sodium fluxes in epithelial cells. Modulation of sodium reabsorption through the distal nephron ENaC is an important component in the overall control of sodium balance, blood volume and thereby of blood pressure. This is clearly demonstrated by rare genetic disorders of
Kelly, Gormley, Yanbin, Dong, Giuseppe A, Sagnella   +2 more
openaire   +2 more sources

Ankyrin G Expression Regulates Apical Delivery of the Epithelial Sodium Channel (ENaC) [PDF]

, 2019
Research paper describing the interaction of the epithelial sodium channel (ENaC) and the scaffolding protein ankyrin G (AnkG) in renal collecting duct ...
Lindsay Kighlinger (6428990), Xiaoning Liu (588784), Robert S. Edinger (131846), Christine A Klemens (6428988), Michael B. Butterworth (131855)   +4 more
core   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Regulation of epithelial sodium channels by cGMP/PKGII

The Journal of Physiology, 2009
Airway and alveolar fluid clearance is mainly governed by vectorial salt movement via apically located rate‐limiting Na+channels (ENaC) and basolateral Na+/K+‐ATPases. ENaC is regulated by a spectrum of protein kinases, i.e. protein kinase A (PKA), C (PKC), and G (PKG).
Hong-Guang, Nie, Lan, Chen, Dong-Yun, Han, Jun, Li, Wei-Feng, Song, Shi-Peng, Wei, Xiao-Hui, Fang, Xiu, Gu, Sadis, Matalon, Hong-Long, Ji   +9 more
openaire   +3 more sources

Epithelial Sodium Channels are Upregulated During Epidermal Differentiation [PDF]

, 1999
Terminal differentiation of epidermal keratinocytes is linked to transmembrane ion flux. Previously, we have shown that amiloride, an inhibitor of epithelial sodium channels, blocks synthesis of differentiation-specific proteins in normal human ...
Oda, Yuko, Largman, Corey, Imanzahrai, Ashkan, Mauro, Theodora, Kömüves, László, Elias, Peter M., Kwong, Angela   +6 more
core   +1 more source

Thermally Modulated Metasurface Sensor for Dynamic and Time‐Resolved Isolation of Extracellular Vesicles

Advanced Materials, EarlyView.
A thermally adaptive plasmonic metasurface, functionalized with poly(N‐isopropylacrylamide) (PNIPAM) and anti‐CD63 antibodies, enables precise, on‐demand capture and release of extracellular vesicles (EVs). Delivering high recovery, improved purity, and intact vesicle structure, the platform offers a versatile, label‐free solution for real‐time EV ...
Beyza Nur Kucuk, Eylul Gulsen Yilmaz, Yusuf Aslan, Emre Ece, Özgecan Erdem, Murat Alp Gungen, Bengi Özgün Öztürk, Fatih Inci   +7 more
wiley   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source