Results 141 to 150 of about 14,256 (219)

Downregulation of epithelial sodium channel (ENaC) activity in human airway epithelia after low temperature incubation. [PDF]

BMJ Open Respir Res, 2021
Yadav S, Shaughnessy CA, Zeitlin PL, Bratcher PE.   +3 more
europepmc   +1 more source

DNA Methylation Patterns Correlate with the Expression of SCNN1A, SCNN1B, and SCNN1G (Epithelial Sodium Channel, ENaC) Genes. [PDF]

Int J Mol Sci, 2021
Pierandrei S, Truglio G, Ceci F, Del Porto P, Bruno SM, Castellani S, Conese M, Ascenzioni F, Lucarelli M.   +8 more
europepmc   +1 more source

The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro [PDF]

, 2017
TMPRSS3 encodes a transmembrane serine protease that contains both LDLRA and SRCR domains and is mutated in non-syndromic autosomal recessive deafness (DFNB8/10).
Antonarakis, Stylianos E., Buchet, Karine, Dougherty, Loretta, Guida, Elizabeth, Guipponi, Michel, Hancock, Manuela, Hummler, Edith, Kudoh, Jun, Marzella, Phillip L., Okui, Michiyo, Reymond, Alexandre, Rossier, Bernard C., Rossier, Colette, Scamuffa, Nathalie, Scott, Hamish S., Shibuya, Kazunori, Shimizu, Nobuyoshi, Vazquez, Maria, Vuagniaux, Grégoire, Wattenhofer, Marie   +19 more
core  

ENaC is a host susceptibility factor to bacterial infections in cystic fibrosis context

Communications Biology
Cystic fibrosis (CF) is a genetic disease caused by dysfunction in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) chloride channel. Patients with CF are hypersusceptible to Mycobacterium abscessus infection, a fast-growing mycobacterium ...
Hamadoun Touré, Nicolas Durand, Mickael Orgeur, Lee Ann Galindo, Fabienne Girard-Misguich, Isabelle Guénal, Jean-Louis Herrmann, Sébastien Szuplewski   +7 more
doaj   +1 more source

Zymogen-locked mutant prostasin (Prss8) leads to incomplete proteolytic activation of the epithelial sodium channel (ENaC) and severely compromises triamterene tolerance in mice. [PDF]

Acta Physiol (Oxf), 2021
Essigke D, Ilyaskin AV, Wörn M, Bohnert BN, Xiao M, Daniel C, Amann K, Birkenfeld AL, Szabo R, Bugge TH, Korbmacher C, Artunc F.   +11 more
europepmc   +1 more source

Dual effect of temperature on the human epithelial Na+ channel [PDF]

, 2018
The amiloride-sensitive epithelial sodium channel (ENaC) is the rate-limiting step for sodium reabsorption in the distal segments of the nephron, in the colon and in the airways.
Chraïbi, Ahmed, Horisberger, Jean-Daniel   +1 more
core  

Dexmedetomidine alleviates pulmonary edema through the epithelial sodium channel (ENaC) via the PI3K/Akt/Nedd4-2 pathway in LPS-induced acute lung injury. [PDF]

Immunol Res, 2021
Jiang Y, Xia M, Xu J, Huang Q, Dai Z, Zhang X.   +5 more
europepmc   +1 more source

CFTR and ENaC functions in cystic fibrosis [PDF]

, 2014
La fibrosis quística se debe a la ausencia o defecto del canal transmembrana regulador de la fibrosis quística (CFTR), un canal de cloruro codificado en el gen cftr que juega un papel clave en la homeostasis del agua e iones.
Kotsias, Basilio Aristides, Marino, Gabriela Inés, Palma, Alejandra Graciela   +2 more
core  

Non-genomic actions of aldosterone: From receptors and signals to membrane targets. [PDF]

, 2011
In tissues which express the mineralocorticoid receptor (MR), aldosterone modulates the expression of membrane targets such as the subunits of the epithelial Na(+) channel, in combination with important signalling intermediates such as serum and ...
Dooley, Ruth, Harvey, Brian J, Thomas, Warren   +2 more
core   +1 more source

Prostaglandin E2 stimulates the epithelial sodium channel (ENaC) in cultured mouse cortical collecting duct cells in an autocrine manner. [PDF]

J Gen Physiol, 2020
Mansley MK, Niklas C, Nacken R, Mandery K, Glaeser H, Fromm MF, Korbmacher C, Bertog M.   +7 more
europepmc   +1 more source