Results 41 to 50 of about 98,993 (345)

A Linear Surface Epitope in a Proline-Rich Region of ORF3 Product of Genotype 1 Hepatitis E Virus

Viruses, 2016
Hepatitis E virus (HEV) is one of the viral pathogens causing hepatitis in humans. HEV open reading frame 3 (ORF3) encodes a small multifunctional protein (VP13), which is essential for HEV infection.
Yonglin Yang, Shaoli Lin, Yuchen Nan, Zexu Ma, Liping Yang, Yanjin Zhang   +5 more
doaj   +1 more source

Identification of hepatitis a virus mimotopes by phage display, antigenicity and immunogenicity [PDF]

, 2007
A phage-displayed peptide approach was used to identify ligands mimicking antigenic determinants of hepatitis A virus (HAV) for the first time. Bacteriophages displaying HAV mimotopes were isolated from a phage-display peptide library by affinity ...
Alicia Aguilar, Altschul, Arturo Talavera, Beales, Beckmann, Bosch, Burritt, Burritt, Clark, Cohen, Collins, Cuthbert, David I. Stott, de la Cruz, Delmastro, Ela M. Perez, Emini, Enshell-Seijffers, Felici, Folgori, Folgori, Frank Camacho, Gomara, Hollinger, Hoogenboon, Irving, Lemon, Lemon, Lemon, Lemon, Lemon, Lemon, Marston, Martin, Mattioli, Nainan, Neduva, Nevis Amin, Osmany G. Larralde, Partidos, Perea, Perez, Ping, Ping, Prezzi, Raiza Martinez, Reed, Sambrook, Scholfield, Stapleton, Stapleton, Stapleton, Verdaguer, Wan, Zhang   +54 more
core   +1 more source

An overview on application of phage display technique in immunological studies

Asian Pacific Journal of Tropical Biomedicine, 2017
Phage display is very strong technique in drug discovery and development. Phage display has many applications in improving the immunological studies. Development of monoclonal antibody, peptides, peptidomimetics and epitope mapping are main application ...
Abbas Rami, Mahdi Behdani, Najmeh Yardehnavi, Mahdi Habibi-Anbouhi, Fatemeh Kazemi-Lomedasht   +4 more
doaj   +1 more source

The unpredictably eruptive dynamics of spruce budworm populations in eastern Canada

Population Ecology, EarlyView.
We examine historical population data for spruce budworm from several locations through the period 1930–1997, and use density‐dependent recruitment curves to test whether the pattern of population growth over time is more consistent with Royama's (1984; Ecological Monographs 54:429–462) linear R(t) model of harmonic oscillation at Green River New ...
Barry J. Cooke, Jacques Régnière
wiley   +1 more source

The Rosetteless gene controls development in the choanoflagellate S. rosetta. [PDF]

, 2014
The origin of animal multicellularity may be reconstructed by comparing animals with one of their closest living relatives, the choanoflagellate Salpingoeca rosetta.
Greaney, Allison J, King, Nicole, Levin, Tera C, Wetzel, Laura   +3 more
core   +1 more source

Dengue virus antibody database: Systematically linking serotype-specificity with epitope mapping in dengue virus. [PDF]

PLoS Neglected Tropical Diseases, 2017
BACKGROUND:A majority infections caused by dengue virus (DENV) are asymptomatic, but a higher incidence of severe illness, such as dengue hemorrhagic fever, is associated with secondary infections, suggesting that pre-existing immunity plays a central ...
Sidhartha Chaudhury, Gregory D Gromowski, Daniel R Ripoll, Ilja V Khavrutskii, Valmik Desai, Anders Wallqvist   +5 more
doaj   +1 more source

MAbTope: A Method for Improved Epitope Mapping [PDF]

The Journal of Immunology, 2018
Abstract Abs are very efficient drugs, ∼70 of them are already approved for medical use, over 500 are in clinical development, and many more are in preclinical development. One important step in the characterization and protection of a therapeutic Ab is the determination of its cognate epitope.
Eric Reiter, Mohammed Akli Ayoub, Mohammed Akli Ayoub, Hervé Watier, Thomas Boulo, Pascale Crépieux, Vincent Puard, Astrid Musnier, Shifa Tahir, Anne Poupon, Gilles Bruneau, Yann Jullian, Thomas Bourquard, Thomas Bourquard, Nathalie Gallay, Nathalie Gallay   +15 more
openaire   +5 more sources

Network topology drives population temporal variability in experimental habitat networks

Population Ecology, EarlyView.
Habitat patches connected by dispersal pathways form habitat networks. We explored how network topology affects population outcomes in laboratory experiments using a model species (Daphnia carinata). Central habitat nodes in complex lattice networks exhibited lower temporal variability in population sizes, suggesting they support more stable ...
Yiwen Xu, J. Angus Webb, William D. Bovill, Elise L. King   +3 more
wiley   +1 more source

Structure-based high-throughput epitope analysis of hexon proteins in B and C species human adenoviruses (HAdVs). [PDF]

PLoS ONE, 2012
Human adenoviruses (HAdVs) are the etiologic agent of many human infectious diseases. The existence of at least 54 different serotypes of HAdVs has resulted in difficulties in clinical diagnosis.
Xiao-Hui Yuan, Ying-Chen Wang, Wen-Jing Jin, Bin-Bin Zhao, Cai-Feng Chen, Jian Yang, Jing-Fei Wang, Ying-Ying Guo, Jing-Jun Liu, Ding Zhang, Lu-Lu Gong, You-Wen He   +11 more
doaj   +1 more source

Geographic variation in walking activity in the red flour beetle Tribolium castaneum

Population Ecology, EarlyView.
This study examined whether there is geographic variation in field populations, focusing on the moving activity in the red flour beetle Tribolium castaneum. Results showed significant differences in moving activity among field populations but no correlation with latitude or meteorological factors.
Kentarou Matsumura
wiley   +1 more source