Human immunodeficiency virus type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzees. [PDF]
Jaap Goudsmit+8 more
openalex +1 more source
IntroductionThe immune response after transplantation depends on recipient/donor HLA allele mismatches. To enhance our understanding of the relations of HLA alleles in terms of amino-acid polymorphisms and shared epitopes, we assessed pairwise sequence ...
Ilias Doxiadis+3 more
doaj +1 more source
N-Glycosylation influences human corticosteroid-binding globulin measurements
Objective: Discrepancies in ELISA measurements of human corticosteroid-binding globulin (CBG) using detection monoclonal antibodies that recognize an epitope (9G12) within its reactive center loop (RCL), versus an epitope (12G2) in a different location ...
Lesley A Hill+5 more
doaj +1 more source
Western and dot immunoblotting analysis of viral antigens and antibodies: application to murine hepatitis virus. [PDF]
Viral proteins were separated by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and transferred quantitatively to nitrocellulose by electroblotting in SDS-containing buffer.
Buchmeier, MJ, Knobler, RL, Talbot, PJ
core
Epitopes of human interferon-alpha defined by the reaction of monoclonal antibodies with alpha interferons and interferon analogues. [PDF]
Joyce Taylor‐Papadimitriou+2 more
openalex +1 more source
The essence of epitopes. [PDF]
L. D. Barber, Peter Parham
openaire +3 more sources
Comprehensive Overview of Broadly Neutralizing Antibodies against SARS-CoV-2 Variants
Currently, SARS-CoV-2 has evolved into various variants, including the numerous highly mutated Omicron sub-lineages, significantly increasing immune evasion ability. The development raises concerns about the possibly diminished effectiveness of available
Lingyan Cui+8 more
doaj +1 more source
Epitope analysis for influenza vaccine design [PDF]
Until now, design of the annual influenza vaccine has relied on phylogenetic or whole-sequence comparisons of the viral coat proteins hemagglutinin and neuraminidase, with vaccine effectiveness assumed to correlate monotonically to the vaccine-influenza sequence difference. We use a theory from statistical mechanics to quantify the non-monotonic immune
arxiv
In vitro and in vivo modification of Neisseria gonorrhoeae lipooligosaccharide epitope structure by sialylation. [PDF]
After growth of gonococci in the presence of cytidine monophospho-N-acetyl-neuraminic acid (CMP-NANA), their 4.5-kD lipooligosaccharide (LOS) component was increased by approximately 400 daltons, whereas the LOS of strains lacking the 4.5-kD component ...
Apicella, MA+9 more
core +1 more source
Serologically defined linear epitopes in the envelope protein of dengue 2 (Jamaica strain 1409) [PDF]
John Aaskov+2 more
openalex +1 more source