Results 111 to 120 of about 228,208 (297)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi+5 more
wiley +1 more source
Natural variation of poliovirus neutralization epitopes [PDF]
R Crainic+5 more
openalex +1 more source
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz+5 more
wiley +1 more source
Preliminary characterization of an epitope involved in neutralization and cell attachment that is located on the major bovine rotavirus glycoprotein [PDF]
Marta Sabara+3 more
openalex +1 more source
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia+5 more
wiley +1 more source
Recent Advances of Processing and Detection Techniques on Crustacean Allergens: A Review
Crustaceans are delicious and highly nutritional food. However, crustaceans are one of the main food allergens, causing severe public health issues.
Xin Qu, Zekun Ma, Xuli Wu, Liangtao Lv
doaj +1 more source
A sequence pattern common to T cell epitopes.
Jonathan B. Rothbard, William R. Taylor
openalex +1 more source
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer+7 more
wiley +1 more source