Results 111 to 120 of about 343,320 (257)

Exploring glutathione transferase and Cathepsin L-like proteinase for designing of epitopes-based vaccine against Fasciola hepatica by immunoinformatics and biophysics studies

open access: yesFrontiers in Immunology
Fasciolosis is a zoonotic infection and is considered a developing deserted tropical illness threatening ruminant productivity and causing financial losses.
Hassan H. Alhassan   +10 more
doaj   +1 more source

Landscape of epitopes targeted by T cells in 852 individuals recovered from COVID-19: Meta-analysis, immunoprevalence, and web platform

open access: yesCell Reports Medicine, 2021
Summary: Knowledge of the epitopes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) targeted by T cells in recovered (convalescent) individuals is important for understanding T cell immunity against coronavirus disease 2019 (COVID-19 ...
Ahmed Abdul Quadeer   +2 more
doaj  

A Nonconventional Analysis of CD$4^{+}$ and CD$8^{+}$ T Cell Responses During and After Acute Lymphocytic Choriomeningitis Virus Infection [PDF]

open access: yesarXiv, 2017
A mathematical model from a previous work was re-fitted and analyzed for experimental data regarding the cellular immune response to the lymphocytic choriomeningitis virus. Specifically, the $CD8^{+}$ T cell response to six MHC class I-restricted epitopes (GP* and NP*) and $CD4^{+}$ T cell responses to two MHC class II-restricted epitopes\cite ...
arxiv  

Non‐Uniform Distribution of Neurofilament Epitopes in the CNS during Developmenta [PDF]

open access: bronze, 1985
Raphael Hofstein   +3 more
openalex   +1 more source

Identification of novel blood-based extracellular vesicles biomarker candidates with potential specificity for traumatic brain injury in polytrauma patients

open access: yesFrontiers in Immunology
ObjectiveThe goal of this study was to identify changes in extracellular vesicles (EV) surface proteins specific to traumatic brain injury (TBI), which could be used as a diagnostic and prognostic tool in polytrauma patients.Summary Background DataKnown ...
Cora R. Schindler   +6 more
doaj   +1 more source

Modelling the effect of antibody depletion on dose-response behavior for common immunostaining protocols [PDF]

open access: yesarXiv
Dose-response curves of immunostaining experiments are commonly described as Langmuir isotherm. However, for common immunostaining protocols the equilibrium assumption is violated and the dose-response behavior is governed by antibody accumulation. If bound antibodies are replenished, i.e.
arxiv  

Predicting Fixation Tendencies of the H3N2 Influenza Virus by Free Energy Calculation [PDF]

open access: yesJ. Chem. Theory Comput. 7 (2011) 1259-1272, 2012
Influenza virus evolves to escape from immune system antibodies that bind to it. We used free energy calculations with Einstein crystals as reference states to calculate the difference of antibody binding free energy ($\Delta\Delta G$) induced by amino acid substitution at each position in epitope B of the H3N2 influenza hemagglutinin, the key target ...
arxiv  

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