Deep Neural Network-Based Prediction of B-Cell Epitopes for SARS-CoV and SARS-CoV-2: Enhancing Vaccine Design through Machine Learning [PDF]
The accurate prediction of B-cell epitopes is critical for guiding vaccine development against infectious diseases, including SARS and COVID-19. This study explores the use of a deep neural network (DNN) model to predict B-cell epitopes for SARS-CoVandSARS-CoV-2,leveraging a dataset that incorporates essential protein and peptide features.
arxiv
Use of a lambda gt11 expression library to localize a neutralizing antibody-binding site in glycoprotein E2 of Sindbis virus [PDF]
The Sindbis virus envelope contains two species of integral membrane glycoproteins, E1 and E2. These proteins form heterodimers, and three dimeric units assemble to form spikes incorporated into the viral surface which play an important role in the ...
Strauss, James H., Wang, Kang-Sheng
core +1 more source
Identification and characterization of T helper epitopes in the nucleoprotein of influenza A virus. [PDF]
Xiao‐Ming Gao, F Y Liew, J P Tite
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This study addresses the crucial protein Internalin A in the development of a possible vaccination against Listeria monocytogenes. A meticulous in silico strategy was used which included physiochemical analysis, epitope prediction, and molecular ...
Tariq Aziz+9 more
doaj +1 more source
Sequence of protective epitopes of streptococcal M proteins shared with cardiac sarcolemmal membranes. [PDF]
Samantha Sargent+3 more
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A protective monoclonal antibody recognizes a variant-specific epitope in the precursor of the major merozoite surface antigen of the rodent malarial parasite Plasmodium yoelii. [PDF]
James M. Burns+5 more
openalex +1 more source
Identification of T epitopes within a potential Plasmodium falciparum vaccine antigen. A study of human lymphocyte responses to repeat and nonrepeat regions of Pf155/RESA. [PDF]
C M Rzepczyk+9 more
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Unique intermolecular bactericidal epitope involving the homosialopolysaccharide capsule on the cell surface of group B Neisseria meningitidis and Escherichia coli K1. [PDF]
Harold J. Jennings+3 more
openalex +1 more source
A sequence pattern common to T cell epitopes.
Jonathan B. Rothbard, William R. Taylor
openalex +1 more source