Modelling the effect of antibody depletion on dose-response behavior for common immunostaining protocols [PDF]
Antibody binding properties for immunostaining applications are often characterized by dose-response curves, which describe the amount of bound antibodies as a function of the antibody concentration applied at the beginning of the experiment. A common model for the dose-response curve is the Langmuir isotherm, which assumes an equilibrium between the ...
arxiv
Delineation of several DR-restricted tetanus toxin T cell epitopes. [PDF]
Stéphane Demotz+5 more
openalex +1 more source
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy+12 more
wiley +1 more source
Antigen Der f I from the dust mite Dermatophagoides farinae: structural comparison with Der p I from Dermatophagoides pteronyssinus and epitope specificity of murine IgG and human IgE antibodies. [PDF]
Peter W. Heymann+2 more
openalex +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia+17 more
wiley +1 more source
Analysis of 17D Yellow Fever Virus Envelope Protein Epitopes Using Monoclonal Antibodies
J. J. Schlesinger+2 more
openalex +1 more source
Molecularly engineered vaccine which expresses an immunodominant T-cell epitope induces cytotoxic T lymphocytes that confer protection from lethal virus infection [PDF]
Linda Klavinskis+2 more
openalex +1 more source
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source
A study on B-cell epitope prediction based on QSVM and VQC [PDF]
This study investigates quantum computing's role in B-cell epitope prediction using Quantum Support Vector Machine (QSVM) and Variational Quantum Classifier (VQC). It highlights the potential of quantum machine learning in bioinformatics, addressing computational efficiency limitations of traditional methods as data complexity grows.
arxiv