Results 211 to 220 of about 228,208 (297)

A Pan-H5N1 Multiepitope DNA Vaccine Construct Targeting Some Key Proteins of the Clade 2.3.4.4b Using AI-Assisted Epitope Mapping and Molecular Docking. [PDF]

Viruses
Duraisamy N, Shah AU, Khan MY, Cherkaoui M, Hemida MG.   +4 more
europepmc   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Considerations on Structural Vaccinology and Epitope Screening of Calcium-Dependent Protein Kinases 8 as a Potential Vaccine Target Against <i>Toxoplasma gondii</i>. [PDF]

Interdiscip Perspect Infect Dis
Abedi A, Ghaffari AD.
europepmc   +1 more source

Preparation and characterization of two monoclonal antibodies against different epitopes in Escherichia coli ribosomal protein L7/L12.

, 1985
Andreas Sommer, James R. Etchison, Grace Gavino, Nick Zecherle, Carlos A. Casiano, Robert R. Traut   +5 more
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Human IgE monoclonal antibodies define two unusual epitopes trapping dog allergen Can f 1 in different conformations. [PDF]

Protein Sci
Khatri K, Ball A, Glesner J, Linn C, Vailes LD, Wünschmann S, Gabel SA, Zhang J, Peebles RS, Borowski T, Mueller GA, Chapman MD, Smith SA, Pomés A, Chruszcz M.   +14 more
europepmc   +1 more source

Analysis of 17D Yellow Fever Virus Envelope Protein Epitopes Using Monoclonal Antibodies

, 1984
J. J. Schlesinger, Edward E. Walsh, M. W. Brandriss   +2 more
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

In Silico Development of a Chimeric Multi-Epitope Vaccine Targeting <i>Helcococcus kunzii</i>: Coupling Subtractive Proteomics and Reverse Vaccinology for Vaccine Target Discovery. [PDF]

Pharmaceuticals (Basel)
Allemailem KS.
europepmc   +1 more source

Monoclonal antibodies against rat brain hexokinase. Utilization in epitope mapping studies and establishment of structure-function relationships.

, 1985
Jonathan E. Wilson, Allen Smith
openalex   +1 more source