Results 31 to 40 of about 343,320 (257)
Mutation Profile of HPV16 L1 and L2 Genes in Different Geographic Areas
Viruses, 2022 The causal relationship between HPV and cervical cancer in association with the high prevalence of high risk HPV genotypes led to the design of HPV vaccines based on the major capsid L1 protein.
Dimitris Tsakogiannis +9 more
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Critical review of conformational B-cell epitope prediction methods [PDF]
Briefings in Bioinformatics, bbac567, 1-9, 2023, 2023 Accurate in-silico prediction of conformational B-cell epitopes would lead to major improvements in disease diagnostics, drug design and vaccine development. A variety of computational methods, mainly based on machine learning approaches, have been developed in the last decades to tackle this challenging problem.
arxiv +1 more source
IgE-binding epitopes: a reappraisal [PDF]
Allergy, 2011 Here, we discuss various questions related to IgE epitopes: What are the technical possibilities and pitfalls, what is currently known, how can we put this information into hypothetical frameworks and the unavoidable question: how useful is this information for patient care or allergenicity prediction?
Aalberse, R.C., Crameri R.
openaire +3 more sources
Designing a Multi-Epitope Vaccine against Toxoplasma gondii: An Immunoinformatics Approach
Vaccines, 2022 Infection with the intracellular apicomplexan parasite Toxoplasma gondii causes serious clinical outcomes in both human and veterinary settings worldwide. Although approximately one-third of the world’s population is infected with T. gondii, an effective
Mutiat Hammed-Akanmu +7 more
doaj +1 more source
CD4+ T-cell responses to Epstein-Barr virus (EBV) latent-cycle antigens and the recognition of EBV-transformed lymphoblastoid cell lines [PDF]
, 2005 There is considerable interest in the potential of Epstein-Barr virus (EBV) latent antigen-specific CD4\(^+\) T cells to act as direct effectors controlling EBV-induced B lymphoproliferations.
Brooks, J. +10 more
core +2 more sources
Quantitative Prediction of Linear B-Cell Epitopes [PDF]
Biomedical Statistics and Informatics. Vol. 2, No.1, 2017, pp.1-3, 2017 In scientific literature, there are many programs that predict linear B-cell epitopes from a protein sequence. Each program generates multiple B-cell epitopes that can be individually studied. This paper defines a function called
arxiv +1 more source
Pteridines, 2007 Functional specificity of a protein is linked to its structure. A growing section of bioinformatics deals with the prediction and visualization of protein 3D structures.
Wiltgen Marco, Tilz Gernot P.
doaj +1 more source
Finding Epitopes with Computers
Chemistry & Biology, 2013 The goal of structural vaccinology is to enable the design and engineering of improved antigens. In a recent issue of Chemistry & Biology, Gourlay and colleagues provided evidence that structure-based computational methods allow prediction of B cell epitopes, a crucial step for antigen selection and optimization in vaccine development.
Rino Rappuoli, Enrico Malito
openaire +3 more sources
Epitope Identification in BEFV Gene for Detecting Effective Points [PDF]
Journal of Advanced Biomedical Sciences, 2022 Background & Objective: The most common cause of milk production loss in cattle and water buffalo is bovine ephemeral fever (BEF). Previous cases have been reported in Iran's south regions, with a low mortality rate.
Shima Molazadeh +3 more
doaj
Cells, 2021 Prediction of linear B cell epitopes is of interest for the production of antigen-specific antibodies and the design of peptide-based vaccines. Here, we present BCEPS, a web server for predicting linear B cell epitopes tailored to select epitopes that ...
Alvaro Ras-Carmona +3 more
doaj +1 more source