Results 101 to 110 of about 4,711 (242)

Epitranscriptomics: Mapping Methods and Beyond [PDF]

BioTechniques, 2018
The field of epigenetics has changed the way we look at both DNA and proteins. Could the same be true for RNA? Joseph Martin discusses. [Graphic: see text]
openaire   +2 more sources

Plant ribosomes as a score to fathom the melody of 2’-O-methylation across evolution

RNA Biology
2’-O-ribose methylation (2’-O-Me) is one of the most common RNA modifications detected in ribosomal RNAs (rRNA) from bacteria to eukaryotic cells. 2’-O-Me favours a specific RNA conformation and protects RNA from hydrolysis.
Sara Alina Neumann, Christine Gaspin, Julio Sáez-Vásquez   +2 more
doaj   +1 more source

Analysis of Transcriptome and Epitranscriptome in Plants Using PacBio Iso-Seq and Nanopore-Based Direct RNA Sequencing

Frontiers in Genetics, 2019
Nanopore sequencing from Oxford Nanopore Technologies (ONT) and Pacific BioSciences (PacBio) single-molecule real-time (SMRT) long-read isoform sequencing (Iso-Seq) are revolutionizing the way transcriptomes are analyzed.
Liangzhen Zhao, Hangxiao Zhang, Markus V. Kohnen, Kasavajhala V. S. K. Prasad, Lianfeng Gu, Anireddy S. N. Reddy   +5 more
doaj   +1 more source

The m6A epitranscriptome opens a new charter in immune system logic [PDF]

, 2020
Zhonghua Ma, Xiangyu Gao, You Shuai, Xiaofang Xing, Jiafu Ji   +4 more
openalex   +1 more source

GPX8 deficiency–induced oxidative stress reprogrammed m6A epitranscriptome of oral cancer cells [PDF]

, 2023
Xun Chen, Lingyu Yuan, Lejia Zhang, Liutao Chen, Yi He, Chao Wang, Jie Wu, Shangwu Chen, Wei Zhao, Dongsheng Yu   +9 more
openalex   +1 more source

The N-6 methyladenosine dynamics in STEMI and the effect of IL-6 inhibition - a hypothesis generating sub-study of the ASSAIL-MI trial

Frontiers in Immunology
BackgroundEpitranscriptomics, with m6A as the most prevalent in mammals, is a novel treatment target for inflammatory diseases, including cardiovascular diseases.
Tuva B. Dahl, Tuva B. Dahl, Ana Quiles-Jiménez, Kaspar Broch, Kaspar Broch, Anne Kristine Anstensrud, Anne Kristine Anstensrud, Lars Gullestad, Lars Gullestad, Lars Gullestad, Geir Ø. Andersen, Geir Ø. Andersen, Ola Kleveland, Jonas Øgaard, Jonas Øgaard, Vigdis Bjerkeli, Vigdis Bjerkeli, Azita Rashidi, Kuan Yang, Kirsten B. Holven, Kirsten B. Holven, Pål Aukrust, Magnar Bjørås, Magnar Bjørås, Camilla Huse, Camilla Huse, Camilla Huse, Bente Halvorsen, Bente Halvorsen   +28 more
doaj   +1 more source

Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data [PDF]

, 2013
A large number of computational methods have been developed for analyzing differential gene expression in RNA-seq data. We describe a comprehensive evaluation of common methods using the SEQC benchmark dataset and ENCODE data. We consider a number of key
Azra Krek, Christopher E Mason, Doron Betel, Franck Rapaport, Mono Pirun, Nicholas D Socci, Paul Zumbo, Raya Khanin, Yupu Liang   +8 more
core   +1 more source

Clinical Perspectives in Epitranscriptomics

Current Opinion in Genetics & Development
Epitranscriptomics, the study of reversible and dynamic chemical marks on the RNA, is rapidly emerging as a pivotal field in post-transcriptional gene expression regulation. Increasing knowledge about epitranscriptomic landscapes implicated in disease pathogenesis proves an invaluable opportunity for the identification of epitranscriptomic biomarkers ...
Eloy Santos-Pujol, Carlos Quero-Dotor, Manel Esteller   +2 more
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Phosphate Limitation Responses in Marine Green Algae Are Linked to Reprogramming of the tRNA Epitranscriptome and Codon Usage Bias [PDF]

, 2023
Elisabeth Hehenberger, Jian Guo, Susanne Wilken, Kenneth D. Hoadley, Lisa Sudek, Camille Poirier, Richard Dannebaum, Edward Susko, Alexandra Z. Worden   +8 more
openalex   +1 more source

Strategic projects [PDF]

, 2021
No abstract ...
 University of Aveiro, Research Support Office
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