Results 91 to 100 of about 14,917 (246)
ESC Heart Failure, Volume 12, Issue 6, Page 3987-3999, December 2025.Proposed management of myo‐pericardial diseases. A systematic interdisciplinary approach to myo‐pericardial disease is essential to reach a correct diagnosis, starting from multiparametric characterization including EKG, echocardiography with GLS, laboratory exams and CMR or, in case of electric or haemodynamic instability, EMB.
Marco Merlo +18 more
wiley +1 more source
Kidney & Blood Pressure Research, 2013 Background/Aims: Prolonged elevation of serum aldosterone leads to renal fibrosis. Inflammation also plays a role in the pathogenesis of renal disease.
Hui Chen +5 more
doaj +1 more source
Contribution of Endogenous Glucocorticoids and Their Intravascular Metabolism by 11β-HSDs to Postangioplasty Neointimal Proliferation in Mice [PDF]
, 2012 Exogenous glucocorticoids inhibit neointimal proliferation in animals. We aime to test the hypothesis that endogenous glucocorticoids influence neointimal proliferation; this may be mediated by effects on systemic risk factors or locally in vessels, and ...
Hadoke, Patrick W. F. +6 more
core +1 more source
Database Analysis of Eplerenone Use in Japanese Hypertensive Patients in Clinical Practice
International Journal of Hypertension, 2019 Eplerenone, a mineralocorticoid receptor antagonist (MRA), is available in Japan, but details of its use in clinical settings have not been thoroughly investigated.
Shoko Takahashi +4 more
doaj +1 more source
Epidermal mineralocorticoid receptor plays beneficial and adverse effects in skin and mediates glucocorticoid responses [PDF]
, 2016 10 páginas, 6 figuras. Contiene material suplementarioGlucocorticoids (GCs) regulate skin homeostasis and combat cutaneous inflammatory diseases; however, adverse effects of chronic GC treatments limit their therapeutic use.
Boix, Julia +4 more
core +1 more source
Salt, Aldosterone, and Parathyroid Hormone: What Is the Relevance for Organ Damage? [PDF]
, 2017 Structured interventions on lifestyle have been suggested as a cost-effective strategy for prevention of cardiovascular disease. Epidemiologic studies demonstrate that dietary salt restriction effectively decreases blood pressure, but its influence on ...
Bertin, Nicole +6 more
core +3 more sources
A Novel Aldosterone Antagonist Limits Renal Injury in 5/6 Nephrectomy
Scientific Reports, 2017 Aldosterone antagonists slow the progression of chronic kidney disease (CKD), but their use is limited by hyperkalemia, especially when associated with RAS inhibitors.
Clarice K. Fujihara +11 more
doaj +1 more source
Orphanet Journal of Rare Diseases, 2017 Background Cardiomyopathy is a leading cause of morbidity and mortality in boys with Duchenne muscular dystrophy (DMD). We recently showed in a 12-month double-blind randomized controlled trial that adding eplerenone to background medical therapy was ...
Subha V. Raman +8 more
doaj +1 more source
Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells [PDF]
, 2017 Vascular calcification resulting from hyperphosphatemia is a major determinant of mortality in chronic kidney disease (CKD). Vascular calcification is driven by aldosterone-sensitive osteogenic transformation of vascular smooth muscle cells (VSMCs).
Alesutan, Ioana +6 more
core +1 more source
New Clinical Aspects of Eplerenone Use in Clinical Practice
Рациональная фармакотерапия в кардиологии, 2018 The problem of the discrepancy between convincing evidences of the effectiveness of the use of mineralocorticoid receptor antagonists in patients with heart failure with reduced left ventricular ejection fraction and insufficiently frequent their use in ...
S. R. Gilyarevskiy +3 more
doaj +1 more source