Results 111 to 120 of about 16,960 (244)

What can we learn from SOCRATES: more questions than answers? [PDF]

, 2017
This editorial refers to ‘Vericiguat in patients with worsening chronic heart failure and preserved ejection fraction: results of the SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with PRESERVED EF (SOCRATES-PRESERVED) Study’, by B ...
Cleland, John G.F., Mueller, Christian
core   +1 more source

Optimizing the diagnosis of primary aldosteronism: The role of adrenal vein sampling and the need for high‐expertise reference centers

Journal of Neuroendocrinology, Volume 38, Issue 4, April 2026.
Abstract Adrenal vein sampling (AVS) is the cornerstone diagnostic procedure for subtype differentiation in primary hyperaldosteronism, guiding therapeutic decision‐making and offering the possibility of curative surgery to a subset of patients.
Aura D. Herrera‐Martínez, Ángel Rebollo‐Román, Pablo Remón‐Ruiz, María José Picón‐César, Patricia Guirado‐Peláez, Carmen Tenorio‐Jiménez, Carlos López‐Pereira, Manuel Aguilar‐Diosdado, Marta Iturregui‐Guevara, Viyey K. Doulatram‐Gamgaram, Maria Eugenia Pérez‐Montilla, Juan José Espejo‐Herrero, Ma Ángeles Galvez‐Moreno, Alfonso Soto‐Moreno, on behalf of the Neuroendocrine Group of the Andalusian Society of Endocrinology, Diabetes and Nutrition   +15 more
wiley   +1 more source

Eplerenone-Mediated Aldosterone Blockade Prevents Renal Fibrosis by Reducing Renal Inflammation, Interstitial Cell Proliferation and Oxidative Stress

Kidney & Blood Pressure Research, 2013
Background/Aims: Prolonged elevation of serum aldosterone leads to renal fibrosis. Inflammation also plays a role in the pathogenesis of renal disease.
Hui Chen, Feng Sun, Xiaoshi Zhong, Yuebin Shao, Ashio Yoshimura, Yan Liu   +5 more
doaj   +1 more source

Effect on Mortality of Higher Versus Lower β-Blocker (Metoprolol Succinate or Carvedilol) Dose in Patients With Heart Failure [PDF]

, 2018
This study aimed to compare the effect of β-blocker dose and heart rate (HR) on mortality in patients with heart failure with reduced ejection fraction (HFrEF).
Ajam, Samer, Ajam, Tarek, Devaraj, Srikant, Fudim, Marat, Kamalesh, Masoor   +4 more
core   +1 more source

The urinary albumin‐to‐creatinine ratio can direct personalized prevention and treatment for cardiovascular and chronic kidney disease

Journal of Internal Medicine, Volume 299, Issue 4, Page 444-466, April 2026.
Abstract Increased urinary albumin excretion is a strong predictor for cardiovascular events in persons with and without decreased glomerular filtration rate and can be assessed with the urinary albumin‐to‐creatinine ratio (UACR), which is a selective, sensitive, and convenient method for patients.
Holly J. Kramer, George L. Bakris
wiley   +1 more source

Aldosterone as a renal growth factor [PDF]

, 2010
Aldosterone regulates blood pressure through its effects on the cardiovascular system and kidney. Aldosterone can also contribute to the development of hypertension that leads to chronic pathologies such as nephropathy and renal fibrosis.
Dooley, Ruth, Harvey, Brian J, Thomas, Warren   +2 more
core   +1 more source

Expert consensus document on the management of hyperkalaemia in patients with cardiovascular disease treated with RAAS-inhibitors - Coordinated by the Working Group on Cardiovascular Pharmacotherapy of the European Society of Cardiology. [PDF]

, 2018
Renin angiotensin aldosterone system inhibitors/antagonists/blockers (RAASi) are a cornerstone in treatment of patients with cardiovascular diseases especially in those with heart failure (HF) due to their proven effect on surrogate and hard end-points ...
Acker, Alfonzo, An, Anker, Bakris, Beusekamp, Bozkurt, Chang, Chen, Clausen, Cooper, Desai, Dittrich, Einhorn, Elliott, Epstein, Epstein, Epstein, Eschalier, Ingelfinger, Jain, Kamel, Kayexalate (sodium polystyrene) [package insert], Khanagavi, Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group, Kjeldsen, Komajda, Lund, Luo, Maggioni, Mancia, Mathialahan, Mattu, McCullough, Molnar, Montalescot, National Institute for Health and Care Excellence (NICE), Packham, Palmer, Perazella, Pitt, Pitt, Pitt, Pitt, Pitt, Ponikowski, Poole-Wilson, Raebel, Ramadan, Rastegar, Rossignol, Rossignol, Rydén, Sarafidis, Shah, Sterns, Takaichi, Tamargo, Tamargo, UK Renal Association, Vardeny, Vardeny, Wei, Weir, Weir, Weir, Weisberg   +66 more
core   +2 more sources

Database Analysis of Eplerenone Use in Japanese Hypertensive Patients in Clinical Practice

International Journal of Hypertension, 2019
Eplerenone, a mineralocorticoid receptor antagonist (MRA), is available in Japan, but details of its use in clinical settings have not been thoroughly investigated.
Shoko Takahashi, Yoichi Ii, Yuji Yamamoto, Aya Ikeda, Yoko Fujimoto   +4 more
doaj   +1 more source

Treatment of Heart Failure with Preserved Ejection Fraction [PDF]

, 2011
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90240/1/phco.31.3.312 ...
Barnes, Megan M., Bleske, Barry E., Dorsch, Michael P., Hummel, Scott L., Koelling, Todd M.   +4 more
core   +1 more source

Eplerenone for early cardiomyopathy in Duchenne muscular dystrophy: results of a two-year open-label extension trial

Orphanet Journal of Rare Diseases, 2017
Background Cardiomyopathy is a leading cause of morbidity and mortality in boys with Duchenne muscular dystrophy (DMD). We recently showed in a 12-month double-blind randomized controlled trial that adding eplerenone to background medical therapy was ...
Subha V. Raman, Kan N. Hor, Wojciech Mazur, Xin He, John T. Kissel, Suzanne Smart, Beth McCarthy, Sharon L. Roble, Linda H. Cripe   +8 more
doaj   +1 more source