Results 121 to 130 of about 16,960 (244)
Salt, Aldosterone, and Parathyroid Hormone: What Is the Relevance for Organ Damage? [PDF]
, 2017 Structured interventions on lifestyle have been suggested as a cost-effective strategy for prevention of cardiovascular disease. Epidemiologic studies demonstrate that dietary salt restriction effectively decreases blood pressure, but its influence on ...
Bertin, Nicole +6 more
core +3 more sources
European Heart Journal, 2016 Aims To evaluate oral doses of the non-steroidal mineralocorticoid receptor antagonist finerenone given for 90 days in patients with worsening heart failure and reduced ejection fraction and chronic kidney disease and/or diabetes mellitus.
G. Filippatos +16 more
semanticscholar +1 more source
New Clinical Aspects of Eplerenone Use in Clinical Practice
Рациональная фармакотерапия в кардиологии, 2018 The problem of the discrepancy between convincing evidences of the effectiveness of the use of mineralocorticoid receptor antagonists in patients with heart failure with reduced left ventricular ejection fraction and insufficiently frequent their use in ...
S. R. Gilyarevskiy +3 more
doaj +1 more source
Epidermal mineralocorticoid receptor plays beneficial and adverse effects in skin and mediates glucocorticoid responses [PDF]
, 2016 10 páginas, 6 figuras. Contiene material suplementarioGlucocorticoids (GCs) regulate skin homeostasis and combat cutaneous inflammatory diseases; however, adverse effects of chronic GC treatments limit their therapeutic use.
Boix, Julia +4 more
core +1 more source
A Novel Aldosterone Antagonist Limits Renal Injury in 5/6 Nephrectomy
Scientific Reports, 2017 Aldosterone antagonists slow the progression of chronic kidney disease (CKD), but their use is limited by hyperkalemia, especially when associated with RAS inhibitors.
Clarice K. Fujihara +11 more
doaj +1 more source
Eplerenone as a novel treatment for persistent subretinal fluid following retinal detachment surgery
American Journal of Ophthalmology Case Reports, 2018 Purpose: To describe the clinical course of a patient with persistent subretinal fluid (SRF) after primary scleral buckle surgery for a rhegmatogenous retinal detachment (RRD) repair who was subsequently treated with oral eplerenone for resolution of SRF.
Arezu Haghighi, Jiun Do, Hossein Ameri
doaj +1 more source
Health Technology Assessment, 2010 Background: Two aldosterone inhibitors are currently licensed for heart failure (HF) in the UK: spironolactone and eplerenone. Recent clinical guidelines recommend eplerenone after an acute myocardial infarction (MI) for patients with symptoms and/or ...
C McKenna +11 more
doaj +1 more source
Interventions for central serous chorioretinopathy: a network meta-analysis. [PDF]
, 2015 BACKGROUND: Central serous chorioretinopathy (CSC) is characterized by serous detachment of the neural retina with dysfunction of the choroid and retinal pigment epithelium (RPE).
Evans, Jennifer R +4 more
core +1 more source
Eplerenone tetrahydrofuran solvate
Acta Crystallographica Section E Structure Reports Online, 2007 The eplerenone molecule of the title compound, C24H30O6·C4H8O, contains three six-membered rings, two five-membered rings and one three-membered ring. In the crystal structure, the eplerenone molecules are linked via C—H⋯O hydrogen bonds, forming a 303 A3 cavity, which is occupied by two disordered solvent THF molecules.
Qian Yang +3 more
openaire +1 more source
Vascular Health and Risk Management, 2018 Mireille Fernet,1 Bruce Beckerman,2 Paula Abreu,2 Katharina Lins,3 John Vincent,2 Ellen Burgess4 1Department of Medical Affairs, Pfizer Canada Inc., Kirkland, QC, Canada; 2Department of Clinical Affairs, Pfizer Inc., New York, NY, USA; 3Department ...
Fernet M +5 more
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