Results 101 to 110 of about 16,960 (244)
Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi +6 more
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background Duchenne muscular dystrophy incurs nearly universal dilated cardiomyopathy by the third decade of life, preceded by myocardial damage and impaired left ventricular strain by cardiac magnetic resonance.
Subha V. Raman +16 more
doaj +1 more source
ESC Heart Failure, 2020 Aims Left ventricular (LV) dysfunction in viral myocarditis is attributed to myocardial inflammation and fibrosis, inducing acute and long‐time cardiac damage. Interventions are not established.
Carsten Tschöpe +12 more
doaj +1 more source
Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: A systematic review and meta-analysis [PDF]
, 2016 Background: Hypertension and proteinuria are critically involved in the progression of chronic kidney disease. Despite treatment with renin angiotensin system inhibition, kidney function declines in many patients.
Boesby, L. (Lene) +16 more
core +1 more source
JGH Open, Volume 10, Issue 4, April 2026.ABSTRACT Background Tolvaptan promotes electrolyte‐free water excretion and is widely used in Asia for ascites, but in Western countries its use is limited to hyponatremia because of hepatotoxicity concerns. Methods We performed a retrospective cohort study using the TriNetX Research Network, emulating a target trial of cirrhotic patients with ...
Kazuya Okushin +5 more
wiley +1 more source
Blood pressure control versus atrial fibrillation management in stroke prevention [PDF]
, 2015 Hypertension is one of the major risk factors for atrial fibrillation which in turn is the most prevalent concomitant condition in hypertensive patients. While both these pathological conditions are independent risk factors for stroke, the association of
Sada, Lidia +2 more
core +1 more source
Journal of Arrhythmia, Volume 42, Issue 2, April 2026.In a real‐world emergency department study of atrial fibrillation and flutter, cardioversion restored sinus rhythm in 68% of patients. Electrical cardioversion achieved the highest success, while pharmacological and mixed strategies predicted failure. Complications were infrequent but clinically significant.
Abid M. Sadiq +3 more
wiley +1 more source
Muscle &Nerve, Volume 73, Issue 4, Page 668-674, April 2026.Pretreatment with an agonist of Kv7 potassium channels (XEN1101) protects the soleus muscle from a loss of force during a 2 mM K+ challenge, in a mouse model of hypokalemic periodic paralysis. ABSTRACT Introduction/Aims Effective management remains lacking for recurrent episodes of acute weakness in hypokalemic periodic paralysis (HypoPP).
Viktor Chanchykov +4 more
wiley +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3137-3145, April 2026.Abstract Aim Heart failure with preserved ejection fraction (HFpEF) presents a therapeutic challenge, characterised by a paucity of validated treatments. Emerging data suggest that targeting adiposity is central to HFpEF pathogenesis. We conducted an updated network meta‐analysis to compare the efficacy of emerging and established HFpEF therapies ...
Szu‐Han Chen +7 more
wiley +1 more source
Willingness to pay for a reduction in the mortality risk after a myocardial infarction: an aplication of the contingent valuation method to the case of eplerenone [PDF]
Background: In order to allocate health care resources more efficiently it is necessary to relate health improvements provided by new medicines with their cost.
Jaime Fernández de Bobadilla +2 more
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