Results 101 to 110 of about 14,917 (246)

A systematic review and economic evaluation of the clinical effectiveness and cost-effectiveness of aldosterone antagonists for postmyocardial infarction heart failure

open access: yesHealth Technology Assessment, 2010
Background: Two aldosterone inhibitors are currently licensed for heart failure (HF) in the UK: spironolactone and eplerenone. Recent clinical guidelines recommend eplerenone after an acute myocardial infarction (MI) for patients with symptoms and/or ...
C McKenna   +11 more
doaj   +1 more source

Eplerenone as a novel treatment for persistent subretinal fluid following retinal detachment surgery

open access: yesAmerican Journal of Ophthalmology Case Reports, 2018
Purpose: To describe the clinical course of a patient with persistent subretinal fluid (SRF) after primary scleral buckle surgery for a rhegmatogenous retinal detachment (RRD) repair who was subsequently treated with oral eplerenone for resolution of SRF.
Arezu Haghighi, Jiun Do, Hossein Ameri
doaj   +1 more source

Which drugs should post-MI patients routinely receive? [PDF]

open access: yes, 2010
patients should be placed on the following medications: antiplatelet agents (strength of recommendation [SOR]: A, meta-analysis for aspirin; A, multiple randomized controlled trials [RCTs] for aspirin plus clopidogrel) a statin; atorvastatin has the best
Holman, John R.   +2 more
core  

The Pathophysiology and Treatment of Hypertension in Patients With Cushing's Syndrome [PDF]

open access: yes, 2019
When hypertension, a pathology that is frequently found in the general population, presents in a young patient, secondary causes such as Cushing's syndrome (CS), a rare disease characterized by long-term elevated cortisol levels, should be considered ...
Barbot, Mattia   +2 more
core   +1 more source

Cardiorenal syndrome [PDF]

open access: yes, 2015
published_or_final_versio
Pai, MCP
core   +1 more source

Combination of ADAM17 knockdown with eplerenone is more effective than single therapy in ameliorating diabetic cardiomyopathy

open access: yesFrontiers in Pharmacology
BackgroundThe renin-angiotensin-aldosterone system (RAAS) members, especially Ang II and aldosterone, play key roles in the pathogenesis of diabetic cardiomyopathy (DCM).
Lin Xie   +6 more
doaj   +1 more source

Eplerenone tetrahydrofuran solvate

open access: yesActa Crystallographica Section E Structure Reports Online, 2007
The eplerenone mol­ecule of the title compound, C24H30O6·C4H8O, contains three six-membered rings, two five-membered rings and one three-membered ring. In the crystal structure, the eplerenone mol­ecules are linked via C—H⋯O hydrogen bonds, forming a 303 A3 cavity, which is occupied by two disordered solvent THF mol­ecules.
Qian Yang   +3 more
openaire   +1 more source

Rationale and design of MinerAlocorticoid Receptor antagonist Tolerability Study‐Heart Failure (ARTS‐HF): a randomized study of finerenone vs. eplerenone in patients who have worsening chronic heart failure with diabetes and/or chronic kidney disease [PDF]

open access: yes, 2015
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/110733/1/ejhf218 ...
Albert   +39 more
core   +2 more sources

What can we learn from SOCRATES: more questions than answers? [PDF]

open access: yes, 2017
This editorial refers to ‘Vericiguat in patients with worsening chronic heart failure and preserved ejection fraction: results of the SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with PRESERVED EF (SOCRATES-PRESERVED) Study’, by B ...
Cleland, John G.F., Mueller, Christian
core   +1 more source

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