Results 101 to 110 of about 14,325 (202)
Orphanet Journal of Rare Diseases, 2017 Background Cardiomyopathy is a leading cause of morbidity and mortality in boys with Duchenne muscular dystrophy (DMD). We recently showed in a 12-month double-blind randomized controlled trial that adding eplerenone to background medical therapy was ...
Subha V. Raman +8 more
doaj +1 more source
New Clinical Aspects of Eplerenone Use in Clinical Practice
Рациональная фармакотерапия в кардиологии, 2018 The problem of the discrepancy between convincing evidences of the effectiveness of the use of mineralocorticoid receptor antagonists in patients with heart failure with reduced left ventricular ejection fraction and insufficiently frequent their use in ...
S. R. Gilyarevskiy +3 more
doaj +1 more source
What can we learn from SOCRATES: more questions than answers? [PDF]
, 2017 This editorial refers to ‘Vericiguat in patients with worsening chronic heart failure and preserved ejection fraction: results of the SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with PRESERVED EF (SOCRATES-PRESERVED) Study’, by B ...
Cleland, John G.F., Mueller, Christian
core +1 more source
A Novel Aldosterone Antagonist Limits Renal Injury in 5/6 Nephrectomy
Scientific Reports, 2017 Aldosterone antagonists slow the progression of chronic kidney disease (CKD), but their use is limited by hyperkalemia, especially when associated with RAS inhibitors.
Clarice K. Fujihara +11 more
doaj +1 more source
Eplerenone as a novel treatment for persistent subretinal fluid following retinal detachment surgery
American Journal of Ophthalmology Case Reports, 2018 Purpose: To describe the clinical course of a patient with persistent subretinal fluid (SRF) after primary scleral buckle surgery for a rhegmatogenous retinal detachment (RRD) repair who was subsequently treated with oral eplerenone for resolution of SRF.
Arezu Haghighi, Jiun Do, Hossein Ameri
doaj +1 more source
Which drugs should post-MI patients routinely receive? [PDF]
, 2010 patients should be placed on the following medications: antiplatelet agents (strength of recommendation [SOR]: A, meta-analysis for aspirin; A, multiple randomized controlled trials [RCTs] for aspirin plus clopidogrel) a statin; atorvastatin has the best
Holman, John R. +2 more
core
Salt, Aldosterone, and Parathyroid Hormone: What Is the Relevance for Organ Damage? [PDF]
, 2017 Structured interventions on lifestyle have been suggested as a cost-effective strategy for prevention of cardiovascular disease. Epidemiologic studies demonstrate that dietary salt restriction effectively decreases blood pressure, but its influence on ...
Bertin, Nicole +6 more
core +3 more sources
Health Technology Assessment, 2010 Background: Two aldosterone inhibitors are currently licensed for heart failure (HF) in the UK: spironolactone and eplerenone. Recent clinical guidelines recommend eplerenone after an acute myocardial infarction (MI) for patients with symptoms and/or ...
C McKenna +11 more
doaj +1 more source
Eplerenone Suppresses Salt-Induced Vascular Endothelial Growth Factor Expression in the Kidney [PDF]
, 2010 Danita Eatman +2 more
openalex +1 more source