Eplerenone tetrahydrofuran solvate
The eplerenone molecule of the title compound, C24H30O6·C4H8O, contains three six-membered rings, two five-membered rings and one three-membered ring. In the crystal structure, the eplerenone molecules are linked via C—H⋯O hydrogen bonds, forming a 303 A3 cavity, which is occupied by two disordered solvent THF molecules.
Qian Yang +3 more
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The Pathophysiology and Treatment of Hypertension in Patients With Cushing's Syndrome [PDF]
When hypertension, a pathology that is frequently found in the general population, presents in a young patient, secondary causes such as Cushing's syndrome (CS), a rare disease characterized by long-term elevated cortisol levels, should be considered ...
Barbot, Mattia +2 more
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Eplerenone Crystal Nanosuspension for Solubility Enhancement: Preparation and Evaluation
Hawraa k. Khafeef, Nawal A. Rajab
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BackgroundThe renin-angiotensin-aldosterone system (RAAS) members, especially Ang II and aldosterone, play key roles in the pathogenesis of diabetic cardiomyopathy (DCM).
Lin Xie +6 more
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B004 Effects of the selective mineralocorticoid receptor antagonist, eplerenone, in a model of aldosterone-induced hypertension and cardiac fibrosis [PDF]
Gregory E. Frierdich
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Remote results of using aldosterone antagonists in complex treatment of patients with myocardial infarction and heart failure [PDF]
The work presents remote results of using aldosterone in complex treatment of patients with myocardial infarction combined with heart failure. It is shown that after using of eplerenone the authenticity of renewal functional indexes of myocardium becomes
Gulaga, O.I. +3 more
core
Тривале спостереження за хворими на гострий інфаркт міокарда при використанні антагоністів альдостерону [PDF]
Проведено аналіз віддалених результатів використання антагоністів альдостерону (спіронолактону та еплеренону) у комплексному лікуванні хворих на інфаркт міокарда з серцевою недостатністю.
Гулага, Ольга Ігорівна +2 more
core
Missed opportunities: low use of evidence-based treatment with eplerenone after myocardial infarction - a nationwide study [PDF]
Siv Mari Berger +7 more
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EPLERENONE TREATMENT FOR SYMPTOMATIC SUBFOVEAL SEROUS PIGMENT EPITHELIAL DETACHMENT
Jayant Kumar +36 more
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Review of: "Eplerenone Reverses Age-Dependent Cardiac Fibrosis Through Downregulating Osteopontin" [PDF]
Anastasios Lymperopoulos
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