Results 61 to 70 of about 6,010 (179)

Epoprostenol Delivered via High Flow Nasal Cannula for ICU Subjects with Severe Hypoxemia Comorbid with Pulmonary Hypertension or Right Heart Dysfunction

Pharmaceutics, 2019
Inhaled epoprostenol (iEPO) has been utilized to improve oxygenation in mechanically ventilated subjects with severe hypoxemia, but the evidence for iEPO via high-flow nasal cannula (HFNC) is rare.
Jie Li, Lauren J. Harnois, Bethelhem Markos, Keith M. Roberts, Salma Al Homoud, Jing Liu, Sara Mirza, David Vines   +7 more
doaj   +1 more source

Observed Weight Gain in Patients With Pulmonary Arterial Hypertension Treated With Sotatercept

Pulmonary Circulation, Volume 16, Issue 3, July 2026.
ABSTRACT Sotatercept, an activin signaling inhibitor for pulmonary arterial hypertension (PAH), has demonstrated significant improvements in clinical outcomes though its off‐target effects are still an area for discovery. Anecdotal increases in total body weight not attributable to fluid retention have been observed.
Rebecca A. Greene, Darlene Tat, Allyson Sherman‐Roe, Tiffaney Cayton, Jacqueline Lopes, Alexander Jorrin, James Klinger, Christopher J. Mullin, Kathryn Needle, William M. Oldham, Crossandra Osgood, Navneet Singh, Corey E. Ventetuolo   +12 more
wiley   +1 more source

Successful use of chronic epoprostenol as a bridge to liver transplantation in severe portopulmonary hypertension

, 1998
Background. Portopulmonary hypertension, defined as mean pulmonary artery pressure \u3e25 mmHg in the presence of a normal pulmonary capillary wedge pressure and portal hypertension, is a known complication of end-stage liver disease that has been ...
Gaine, Sean, Lim, James W., Laurin, Jacqueline, Kuo, Paul C., Njoku, Mary J., Johnson, Lynt B., Plotkin, Jeffrey S., Rubin, Lewis J., Howell, Charles D.   +8 more
core   +1 more source

Invasive Management for Acute‐on‐Chronic Thromboembolic Pulmonary Hypertension: Feasibility and Clinical Outcomes in a Single‐Center Cohort

Pulmonary Circulation, Volume 16, Issue 3, July 2026.
In this single‐center cohort of 15 critically ill patients with acute‐on‐chronic thromboembolic pulmonary hypertension, invasive management with pulmonary endarterectomy and/or balloon pulmonary angioplasty was associated with substantial hemodynamic improvement.
Jun Yamashita, Ryosuke Ito, Sayo Ikeda, Koki Hasegawa, Yoshikazu Takeuchi, Tomohiro Kasahara, Naotaka Murata, Shun Suzuki, Hideaki Kanazawa, Yusuke Shimahara, Kazuhiro Satomi   +10 more
wiley   +1 more source

Cost Implications of Using Inhaled Nitric Oxide Compared with Epoprostenol for Pulmonary Hypertension

, 1995
Objective: To compare the cost of using intravenous epoprostenol with that of inhaled nitric oxide (NO) for treating episodes of pulmonary hypertension in children with congenital heart disease.
Andy J Petros, Sean C Turner, Anthony J Nunn   +2 more
core   +1 more source

Acute effects of nebulised epoprostenol in pulmonary hypertension due to systemic sclerosis [PDF]

, 1999
Pulmonary hypertension often has a lethal outcome in systemic sclerosis and the treatment is challenging. Epoprostenol is a potent pulmonary vasodilator and its efficacy has been demonstrated when delivered by the intravenous and aerosolized routes.
Holland, C., Purcell, I., Taylor, I.K., Keaney, N.P., Farrer, M., Parameswaran, K.   +5 more
core   +1 more source

Right ventricular reverse remodelling in Idiopathic Pulmonary Arterial Hypertension diagnosed during pregnancy: Is it possible?

Respiratory Medicine Case Reports, 2017
We present a case of a 36-year-old woman who developed a severe form of Idiopathic Pulmonary Arterial Hypertension (IPAH) during pregnancy and after emergency delivery. The management of IPAH during or after pregnancy is complex.
Giuseppe Paciocco, Andrea Lombi, Antonella Vincenzi, Alberto Pesci, Felice Achilli   +4 more
doaj   +1 more source

Successful use of inhaled epoprostenol as rescue therapy for pediatric ARDS

Respiratory Medicine Case Reports, 2020
Severe pediatric ARDS remains a significant challenge for clinicians, and management strategies are essentially limited to lung protective ventilation strategies, and adjunct approaches such as prone positioning, steroids, surfactant, and inhaled nitric ...
Alissa Urich, Hammad A. Ganatra, Apurva K. Panchal   +2 more
doaj   +1 more source

Multimodal Assessment of Kidney Quality During 24‐h of Normothermic Machine Perfusion

Artificial Organs, Volume 50, Issue 6, Page 851-865, June 2026.
Normothermic machine perfusion (NMP) has emerged as a promising tool for assessing kidney quality prior to transplantation; however, reliable biomarkers remain to be established. In this study, thirteen porcine kidneys were perfused for 24 h using an autologous leukocyte‐filtered whole blood‐based perfusate applying urine recirculation.
Marlene Pühringer, Magdalena Kött, Andras T. Meszaros, Michael J. Blumer, Bettina Zelger, Stefan Redl, Martin Hermann, Thomas Resch, Simon Mathis, Gabriel Putzer, Judith Martini, Christina Bogensperger, Franka Messner, Julia Hofmann, Margot Fodor, Andrea Griesmacher, Annemarie Weissenbacher, Theresa Hautz, Gert Mayer, Hannes Neuwirt, Gerald Brandacher, Silvia Oberparleiter, Stefan Schneeberger   +22 more
wiley   +1 more source

Vascular health and exercise in females throughout the lifespan: Exploring puberty, pregnancy and menopause

Experimental Physiology, Volume 111, Issue 6, Page 2840-2859, 1 June 2026.
Abstract This narrative review highlights the impact of exercise on vascular health in females over the lifespan with an emphasis on puberty, pregnancy and menopause. These events encompass substantial changes in sex hormone levels, particularly oestrogens and progesterone.
Kathleen B. Miller, M. Erin Moir, Brandon G. Fico   +2 more
wiley   +1 more source