Results 61 to 70 of about 3,579 (191)

Comparison of Tranexamic Acid and Aminocaproic Acid in Coronary Bypass Surgery [PDF]

open access: yes, 2016
OBJECTIVE: Tranexamic acid (TXA) and ɛ-aminocaproic acid (EACA) are used in coronary bypass surgery for antifibrinolytic therapy. Since the removal of aprotinin, data directly comparing their blood sparing effect and their side effects is still missing ...
LeCleir, Lisa K
core   +1 more source

Nitrogen‐Centered Radical‐Directed C(sp3)−H Amination and Aminoalkylation Using (Diarylmethylene)amino Benziodoxolones

open access: yesChemistryEurope, Volume 3, Issue 6, November 11, 2025.
This report describes a C(sp3)−H aminofunctionalization via the photoexcitation of (diarylmethylene)amino benziodoxolones. These iodine reagents act as both single‐electron oxidants and nitrogen‐based SOMOphiles, serving as iminyl radicals, enabling the site‐selective C(sp3)−H amination and aminoalkylation of α‐aminoxy acid derivatives.
Kensuke Kiyokawa   +5 more
wiley   +1 more source

A Case Report on the Surgical Extraction of a Third Molar in a Patient with Bernard–Soulier Syndrome, an Uncommon Disease

open access: yesIndian Journal of Dental Sciences
We present a case of a patient with Bernard–Soulier syndrome (BSS) who had his impacted third mandibular molar surgically extracted. An uncommon congenital bleeding condition called BSS is inherited in an autosomal recessive fashion.
Ashish Kamboj   +4 more
doaj   +1 more source

Massive Bleeding as the First Clinical Manifestation of Metastatic Prostate Cancer due to Disseminated Intravascular Coagulation with Enhanced Fibrinolysis

open access: yesCase Reports in Hematology, 2016
Disseminated intravascular coagulation (DIC) is the most frequent coagulation disorder associated with metastatic prostate adenocarcinoma. However, DIC with enhanced fibrinolysis as an initial presentation of prostate cancer is extremely rare.
Mónica Palma Anselmo   +4 more
doaj   +1 more source

A study of the interaction between Helicobacter pylori and components of the human fibrinolytic system

open access: yesBrazilian Journal of Medical and Biological Research, 2000
The interaction of plasminogen, tissue plasminogen activator (t-PA) and urokinase with a clinical strain of Helicobacter pylori was studied. Plasminogen bound to the surface of H. pylori cells in a concentration-dependent manner and could be activated to
A. Yarzábal   +5 more
doaj   +1 more source

Consensus statement on the diagnosis, management, and treatment of angioedema mediated by Bradykinin. Part. II: treatment, follow-up, and special situations [PDF]

open access: yes, 2011
Background: There are no previous Spanish guidelines or consensus statements on bradykinin-induced angioedema. Aim: To draft a consensus statement on the management and treatment of angioedema mediated by bradykinin in light of currently available ...
Baeza, M. L.   +17 more
core   +1 more source

Enterococcus faecalis Translocation in Sepsis: Fibrinolysis and Mitochondrial Dysfunction Drive Lung Injury

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.
ABSTRACT Sepsis frequently progresses to acute lung injury (ALI), characterised by inflammation, extracellular matrix degradation, and mitochondrial dysfunction. This study identifies Enterococcus faecalis as a gut‐derived bacterium that exploits the host fibrinolytic system for pulmonary translocation, resulting in mitochondrial damage and ...
Chenfei Wang   +6 more
wiley   +1 more source

Immunochemistry of human Lp[a]: characterization of monoclonal antibodies that cross-react strongly with plasminogen.

open access: yesJournal of Lipid Research, 1991
Forty different monoclonal antibodies were produced from hybridomas that were raised against human Lp[a]. Of these, 14 strongly cross-reacted with plasminogen on ELISA screening assays while 16 clearly did not and 10 were only marginally cross-reactive ...
MA Lafferty, AM Salamon, DC Usher
doaj   +1 more source

The Optimal Dose, Efficacy and Safety of Tranexamic Acid on Hemorrhage Control for High Tibial Osteotomy: A Network Meta‐Analysis

open access: yesOrthopaedic Surgery, Volume 17, Issue 10, Page 2784-2808, October 2025.
Effect of TXA doses on outcomes for HTO patients. ABSTRACT Objective This systematic review and network meta‐analysis was performed to explore the optimal dose, efficacy, and safety of tranexamic acid (TXA) treatments versus placebo for high tibial osteotomy (HTO) patients.
Zhihu Zhao   +3 more
wiley   +1 more source

The use of fibrinolysis inhibitors in cardiac surgery with cardiopulmonary bypass (literature review)

open access: yesВестник анестезиологии и реаниматологии
In cardiac surgery with cardiopulmonary bypass (CPB) is a common complication. The incidence of this complication in cardiac surgery patients is estimated at about 10%.
V. Yu. Medvedeva   +3 more
doaj   +1 more source

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