Results 61 to 70 of about 11,106 (236)

Are antifibrinolytic drugs equivalent in reducing blood loss and transfusion in cardiac surgery? A meta-analysis of randomized head-to-head trials [PDF]

, 2005
BACKGROUND: Aprotinin has been shown to be effective in reducing peri-operative blood loss and the need for re-operation due to continued bleeding in cardiac surgery.
A Laupacis, A Menichetti, A Penta de Peppo, Annette J Moxey, B Blauhut, B Eberle, Barrie J Stokes, BI Wong, BL Wiens, C Isetta, CJ Dunn, CR Smith, D Fergusson, DA Henry, David A Henry, DE Warn, E Bennett-Guerrero, E Bennett-Guerrero, F Bernet, G Cohen, GA Nuttall, H Fritz, JB Rich, JF Hardy, JJ Corbeau, JJ Munoz, K Dickersin, KF Schulz, M Clarke, M Levi, M Misfeld, MJ Ray, ML Pinosky, P Maineri, Paul A Carless, PD Mongan, PE Greilich, R DerSimonian, RG Speekenbrink, SC Pugh, SE Fremes, The Cochrane Collaboration Software Development Group, V Casati, V Casati   +43 more
core   +3 more sources

Innovative Hydrogel Design: Tailoring Immunomodulation for Optimal Chronic Wound Recovery

Advanced Science, Volume 12, Issue 2, January 13, 2025.
Here, it is summarized advanced technologies for rationally designing immunomodulatory hydrogels to control macrophage polarization, including controlled immune stimulation through hydrogel chemistry and cell/molecules integration, as well as surface modification, reviewing the influence of hydrogel properties on immunogenic features and chronic wound ...
Chun‐Mei Lai, Wei‐Ji Chen, Yuan Qin, Di Xu, Yue‐Kun Lai, Shao‐Hua He   +5 more
wiley   +1 more source

Enabling icIEF Peak Identification of AAV Capsid Proteins by Fractionation on MauriceFlex and Subsequent Analysis by LC–MS

ELECTROPHORESIS, Volume 46, Issue 1-2, Page 22-33, January 2025.
ABSTRACT A significant limitation of imaged capillary electric focusing (icIEF) is the inability to identify and characterize specific species in the electropherogram. This has led to the development of complementary ion‐exchange chromatography (IEX)‐based methods that are amenable to either fraction collection and subsequent characterization or online
Will McElroy, Sisi Huang, Xiaoping He, Cheng Zhou, Christopher D. Heger, Thomas W. Powers, Melissa M. Anderson, Courtney Sloan, Thomas F. Lerch   +8 more
wiley   +1 more source

Consensus statement on the diagnosis, management, and treatment of angioedema mediated by Bradykinin. Part. II: treatment, follow-up, and special situations [PDF]

, 2011
Background: There are no previous Spanish guidelines or consensus statements on bradykinin-induced angioedema. Aim: To draft a consensus statement on the management and treatment of angioedema mediated by bradykinin in light of currently available ...
Baeza, M. L., Caballero, T., Cabañas, R., Campos, A., Cimbollek, S., González-Quevedo, T., Guilarte, M., Gómez-Traseira, C., Jurado-Palomo, J., Larco, J. I., López-Serrano, M. C., López-Trascasa, Margarita, Marcos, C., Muñoz- Caro, J. M., Pedrosa, M., Prior, N., Rubio, M., Sala-Cunill, A.   +17 more
core   +1 more source

Evaluation of Methods Employed in Establishing Preclinical Similarity of Adalimumab Biosimilars

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2025, Issue 1, 2025.
Adalimumab, marketed as Humira, is a fully humanized monoclonal antibody that blocks the activity of tumor necrosis factor‐alpha and is used in treating several autoimmune disorders. As one of the top‐grossing pharmaceuticals, its global sales surpassed $20 billion in 2023, leading to significant biosimilar development, with 10 products available by ...
Ramya Nair, Naveen Krishnan, Vasudev Shenoy, Raviraja N. Seetharam, Koteshwara Mudigonda   +4 more
wiley   +1 more source

Treatment of Melasma With Q‐Switched Laser in Combination With Tranexamic Acid

Dermatology Research and Practice, Volume 2025, Issue 1, 2025.
Melasma, a pigmentary disorder that particularly affects Asian women, has been clinically proven to respond effectively to combination therapy of Q‐switched lasers and tranexamic acid (TXA), especially with the advancements in laser aesthetics in recent years. However, treatment outcomes can be influenced by factors such as the wavelength and spot size
Zirui Liu, Enzo Errichetti
wiley   +1 more source

An Advanced Mechanically Active Osteoarthritis‐on‐Chip Model to Test Injectable Therapeutic Formulations: The SYN321 Case Study

Advanced Healthcare Materials, Volume 13, Issue 32, December 27, 2024.
The uBeat® MultiCompress platform offers a novel approach for studying injectable therapies on human osteoarthritic (OA) cartilage microtissues in a physiologically‐ and mechanically‐relevant environment. It can accommodate therapeutic formulations like SYN321, a promising diclofenac‐sodium hyaluronate conjugate for knee OA treatment.
Cecilia Palma, Stefano Piazza, Roberta Visone, Rune Ringom, Ulf Björklund, Antonio Bermejo Gómez, Marco Rasponi, Paola Occhetta   +7 more
wiley   +1 more source

Hereditary angioedema in pregnancy and management without recombinant human C1-INH [PDF]

, 2021
A pregnant woman diagnosed with type 1 angioedema seeks care at a public hospital for planning the delivery. This report presents ways to prevent and manage an acute HAE crisis during childbirth and early postpartum without the availability of first-line
Behenck, Gabrielle, Castilhos, Fernanda Oliveira, Maltauro, Daniele Camila, Pilati, Natália Paseto, Stuczynski, Eduardo Vettorazzi, Valério, Edimárlei Gonsales, Vettorazzi, Janete, Vettori, Daniela Vanessa, Zanatta, Maria Alexandrina   +8 more
core  

Crystallization‐Based Separation of ε‐Caprolactam from a Depolymerization Reaction Mixture – Fundamentals and Potential Separation Strategies

Chemie Ingenieur Technik, Volume 96, Issue 12, Page 1620-1631, December 2024.
After depolymerization, ε‐caprolactam can be isolated by crystallization. Two approaches and their thermodynamic bases were investigated: direct crystallization from the reactor effluent or crystallization after liquid‐liquid extraction. Various solid‐liquid equilibria and liquid‐liquid equilibria were studied experimentally and via thermodynamic ...
Axel Schultheis, Vico Tenberg, Liisa Rihko‐Struckmann, Kai Sundmacher, Heike Lorenz   +4 more
wiley   +1 more source

Could We Know epsilon-Aminocaproic Acid Level During Cardiopulmonary Bypass?

, 1998
Elliott Bennett‐Guerrero, Michael G. Mythen   +1 more
  +5 more sources