Untersuchung des Epsilon-Toxins und Mutanten des Epsilon-Toxins aus Clostridium perfringens auf Kanalbildung [PDF]
, 2006 Ziel dieser Arbeit war die biophysikalische Charakterisierung der Bindekomponente des Epsilon-Toxins und der Epsilon-Toxin-Mutanten mit Hilfe künstlicher Lipid-Bilayer-Messungen. Es galt herauszufinden, welcher Teil des Epsilon-Toxins für die Kanalbildung verantwortlich ist, um somit die kanalbildende Domäne definieren zu können.
openaire
Advanced Science, EarlyView.A self‐supporting, biocompatible, and biodegradable 3D cellulose scaffold has been developed for efficient isolation and in situ expansion of circulating tumor cells (CTCs) from patient blood. Subsequently, the 3D cellulose scaffold with cultured CTCs is directly implanted into immunodeficient mice for constructing patient CTC‐derived xenograft (CDX ...
Yi‐Ke Wang +9 more
wiley +1 more source
Evaluation of humoral immune responses against C. perfringens epsilon toxin in Iranian sheep and goats after vaccination. [PDF]
Vet Anim Sci, 2023 Asadi A, Khiav LA, Emadi A, Dadar M.
europepmc +1 more source
Antibacterial activity of different organic honeys against food pathogenic bacterium Clostridium perfringens [PDF]
, 2014 Clostridium perfringens is one of the most common causes of food poisonings and is known to cause human and animal diseases. It has been reported that C. perfringens has developed resistance to antibiotics.
Lyhs, Ulrike +2 more
core
Advanced Science, EarlyView.This study, through multi‐omics approaches and animal models, revealed that air pollutant PM10 exacerbates the progression of rheumatoid arthritis (RA) by suppressing FNBP1 expression and impairing the cytotoxic function of CD56dim NK cells. The “PM10–FNBP1–NK cells” axis provided novel insights into the environmental pathogenesis of RA and suggested ...
Runhan Zhao +11 more
wiley +1 more source
Clostridium epsilon toxin is excessive in multiple sclerosis and provokes multifocal lesions in mouse models. [PDF]
J Clin Invest, 2023 Reder AT.
europepmc +1 more source
Advanced Science, EarlyView.General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen +11 more
wiley +1 more source
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Advanced Science, EarlyView.Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Epsilon toxin-producing Clostridium perfringens colonize the multiple sclerosis gut microbiome overcoming CNS immune privilege. [PDF]
J Clin Invest, 2023 Ma Y +32 more
europepmc +1 more source
Preliminary screening for toxin genes amongst stock cultures of Clostridium perfringens strains isolated from dogs and calves [PDF]
, 2014 The spectrum of Clostridium perfringens infections ranges from food toxino-sis to myonecrosis. In the current study, whole cell protein and toxin gene types were profiled in 12 randomly selected C.
Egwari, L. O. +2 more
core